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DC-SIGN mediated sphingomyelinase-activation and ceramide generation is essential for enhancement of viral uptake in dendritic cells

PLoS pathogens, 2011-02, Vol.7 (2), p.e1001290-e1001290

2011

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The Manifold Roles of Sphingolipids in Viral Infections

Frontiers in physiology, 2021-09, Vol.12, p.715527-715527

2021

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The Role of Neutral Sphingomyelinase-2 (NSM2) in the Control of Neutral Lipid Storage in T Cells

International journal of molecular sciences, 2024-03, Vol.25 (6), p.3247

2024

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Measles Virus Transmission from Dendritic Cells to T Cells: Formation of Synapse-Like Interfaces Concentrating Viral and Cellular Components

Journal of Virology, 2012-09, Vol.86 (18), p.9773-9781

2012

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Neutral sphingomyelinase in physiological and measles virus induced T cell suppression

PLoS pathogens, 2014-12, Vol.10 (12), p.e1004574-e1004574

2014

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Dynamic changes in the proximitome of neutral sphingomyelinase-2 (nSMase2) in TNFα stimulated Jurkat cells

Frontiers in immunology, 2024-07, Vol.15, p.1435701

2024

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The Role of Sphingomyelin Breakdown in Measles Virus Immunmodulation

Cellular physiology and biochemistry, 2014-01, Vol.34 (1), p.20-26

2014

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Sphingomyelin Breakdown in T Cells: Role of Membrane Compartmentalization in T Cell Signaling and Interference by a Pathogen

Frontiers in cell and developmental biology, 2019-08, Vol.7, p.152-152

2019

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The Activity of the Neutral Sphingomyelinase Is Important in T Cell Recruitment and Directional Migration

Frontiers in immunology, 2017-08, Vol.8, p.1007-1007

2017

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Measles Virus Infection Fosters Dendritic Cell Motility in a 3D Environment to Enhance Transmission to Target Cells in the Respiratory Epithelium

Frontiers in immunology, 2019-06, Vol.10, p.1294-1294

2019

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The Neutral Sphingomyelinase 2 Is Required to Polarize and Sustain T Cell Receptor Signaling

Frontiers in immunology, 2018-04, Vol.9, p.815-815

2018

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Hemagglutinin Protein of Wild-Type Measles Virus Activates Toll-Like Receptor 2 Signaling

Journal of Virology, 2002-09, Vol.76 (17), p.8729-8736

2002

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Neutral Sphingomyelinase-2 (NSM 2) Controls T Cell Metabolic Homeostasis and Reprogramming During Activation

Frontiers in molecular biosciences, 2020-09, Vol.7, p.217-217

2020

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Role of Neutral Sphingomyelinase-2 (NSM 2) in the Control of T Cell Plasma Membrane Lipid Composition and Cholesterol Homeostasis

Frontiers in cell and developmental biology, 2019-10, Vol.7, p.226-226

2019

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Induction of membrane ceramides: a novel strategy to interfere with T lymphocyte cytoskeletal reorganisation in viral immunosuppression

PLoS pathogens, 2009-10, Vol.5 (10), p.e1000623-e1000623

2009

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Accumulation of splice variants and transcripts in response to PI3K inhibition in T cells

PloS one, 2013-02, Vol.8 (2), p.e50695-e50695

2013

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Detection of Functionalized Sphingolipid Analogs in Detergent-Resistant Membranes of Immune Cells

Methods in molecular biology (Clifton, N.J.), 2021, Vol.2187, p.313

2021

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Measles Virus Interacts with and Alters Signal Transduction in T-Cell Lipid Rafts

Journal of Virology, 2004-09, Vol.78 (17), p.9552-9559

2004

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The neutral sphingomyelinase 2 in T cell receptor signaling and polarity

Biological chemistry, 2018-09, Vol.399 (10), p.1147

2018

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Disruption of Akt kinase activation is important for immunosuppression induced by measles virus

Nature medicine, 2001-06, Vol.7 (6), p.725-731

2001

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Cytoskeletal dynamics: concepts in measles virus replication and immunomodulation

Viruses, 2011-02, Vol.3 (2), p.102-117

2011

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Inhibition of Acid Sphingomyelinase Allows for Selective Targeting of CD4+ Conventional versus Foxp3+ Regulatory T Cells

The Journal of immunology (1950), 2016-10, Vol.197 (8), p.3130-3141

2016

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Neisseria meningitidis Type IV Pili Trigger Ca 2+ -Dependent Lysosomal Trafficking of the Acid Sphingomyelinase To Enhance Surface Ceramide Levels

Infection and immunity, 2019-08, Vol.87 (8)

2019

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Neisseria meningitidis Type IV Pili Trigger Ca2+-Dependent Lysosomal Trafficking of the Acid Sphingomyelinase To Enhance Surface Ceramide Levels

Infection and immunity, 2019-08, Vol.87 (8)

2019

Volltextzugriff (PDF)

Preculture of PBMCs at high cell density increases sensitivity of T-cell responses, revealing cytokine release by CD28 superagonist TGN1412

Blood, 2011-12, Vol.118 (26), p.6772-6782

2011

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DC-SIGN mediated sphingomyelinase-activation and ceramide generation is essential for enhancement of viral uptake in dendritic cells

The Manifold Roles of Sphingolipids in Viral Infections

The Role of Neutral Sphingomyelinase-2 (NSM2) in the Control of Neutral Lipid Storage in T Cells

Measles Virus Transmission from Dendritic Cells to T Cells: Formation of Synapse-Like Interfaces Concentrating Viral and Cellular Components

Neutral sphingomyelinase in physiological and measles virus induced T cell suppression

Dynamic changes in the proximitome of neutral sphingomyelinase-2 (nSMase2) in TNFα stimulated Jurkat cells

The Role of Sphingomyelin Breakdown in Measles Virus Immunmodulation

Sphingomyelin Breakdown in T Cells: Role of Membrane Compartmentalization in T Cell Signaling and Interference by a Pathogen

The Activity of the Neutral Sphingomyelinase Is Important in T Cell Recruitment and Directional Migration

Measles Virus Infection Fosters Dendritic Cell Motility in a 3D Environment to Enhance Transmission to Target Cells in the Respiratory Epithelium

The Neutral Sphingomyelinase 2 Is Required to Polarize and Sustain T Cell Receptor Signaling

Hemagglutinin Protein of Wild-Type Measles Virus Activates Toll-Like Receptor 2 Signaling

Neutral Sphingomyelinase-2 (NSM 2) Controls T Cell Metabolic Homeostasis and Reprogramming During Activation

Role of Neutral Sphingomyelinase-2 (NSM 2) in the Control of T Cell Plasma Membrane Lipid Composition and Cholesterol Homeostasis

Induction of membrane ceramides: a novel strategy to interfere with T lymphocyte cytoskeletal reorganisation in viral immunosuppression

Accumulation of splice variants and transcripts in response to PI3K inhibition in T cells

Detection of Functionalized Sphingolipid Analogs in Detergent-Resistant Membranes of Immune Cells

Measles Virus Interacts with and Alters Signal Transduction in T-Cell Lipid Rafts

The neutral sphingomyelinase 2 in T cell receptor signaling and polarity

Disruption of Akt kinase activation is important for immunosuppression induced by measles virus

Cytoskeletal dynamics: concepts in measles virus replication and immunomodulation

Inhibition of Acid Sphingomyelinase Allows for Selective Targeting of CD4+ Conventional versus Foxp3+ Regulatory T Cells

Neisseria meningitidis Type IV Pili Trigger Ca 2+ -Dependent Lysosomal Trafficking of the Acid Sphingomyelinase To Enhance Surface Ceramide Levels

Neisseria meningitidis Type IV Pili Trigger Ca2+-Dependent Lysosomal Trafficking of the Acid Sphingomyelinase To Enhance Surface Ceramide Levels

Preculture of PBMCs at high cell density increases sensitivity of T-cell responses, revealing cytokine release by CD28 superagonist TGN1412

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