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HDAC6 regulates epidermal growth factor receptor (EGFR) endocytic trafficking and degradation in renal epithelial cells

PloS one, 2012-11, Vol.7 (11), p.e49418

2012

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Sirtuin 1 inhibition delays cyst formation in autosomal-dominant polycystic kidney disease

The Journal of clinical investigation, 2013-07, Vol.123 (7), p.3084-3098

2013

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New approaches to the autosomal recessive polycystic kidney disease patient with dual kidney-liver complications

Pediatric transplantation, 2013-06, Vol.17 (4), p.328-335

2013

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Src Inhibition Ameliorates Polycystic Kidney Disease

Journal of the American Society of Nephrology, 2008-07, Vol.19 (7), p.1331-1341

2008

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Pathophysiology of childhood polycystic kidney diseases: new insights into disease-specific therapy

Pediatric research, 2014-01, Vol.75 (1-2), p.148-157

2014

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Diagnosis and management of childhood polycystic kidney disease

Pediatric nephrology (Berlin, West), 2011-05, Vol.26 (5), p.675-692

2011

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Molecular and cellular pathophysiology of autosomal recessive polycystic kidney disease (ARPKD)

Cell and tissue research, 2006-12, Vol.326 (3), p.671-685

2006

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Smac-Mimetic―Induced Epithelial Cell Death Reduces the Growth of Renal Cysts

Journal of the American Society of Nephrology, 2013-12, Vol.24 (12), p.2010-2022

2013

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PKHD1, the Polycystic Kidney and Hepatic Disease 1 Gene, Encodes a Novel Large Protein Containing Multiple Immunoglobulin-Like Plexin-Transcription–Factor Domains and Parallel Beta-Helix 1 Repeats

American journal of human genetics, 2002-05, Vol.70 (5), p.1305-1317

2002

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Loss of activator of G‐protein signaling 3 impairs renal tubular regeneration following acute kidney injury in rodents

The FASEB journal, 2011-06, Vol.25 (6), p.1844-1855

2011

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G-protein signaling modulator 1 deficiency accelerates cystic disease in an orthologous mouse model of autosomal dominant polycystic kidney disease

Proceedings of the National Academy of Sciences - PNAS, 2012-12, Vol.109 (52), p.21462-21467

2012

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20-HETE Mediates Proliferation of Renal Epithelial Cells in Polycystic Kidney Disease

Journal of the American Society of Nephrology, 2008-10, Vol.19 (10), p.1929-1939

2008

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20-HETE activates the Raf/MEK/ERK pathway in renal epithelial cells through an EGFR- and c-Src-dependent mechanism

American Journal of Physiology - Renal Physiology, 2009-09, Vol.297 (3), p.F662-F670

2009

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EGF receptor tyrosine kinase inhibition attenuates the development of PKD in Han:SPRD rats

Kidney international, 2003-11, Vol.64 (5), p.1573-1579

2003

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Role of genetic modifiers in an orthologous rat model of ARPKD

Physiological genomics, 2012-08, Vol.44 (15), p.741-753

2012

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Emerging Therapies for Childhood Polycystic Kidney Disease

Frontiers in pediatrics, 2017-04, Vol.5, p.77-77

2017

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Autosomal recessive polycystic kidney disease and congenital hepatic fibrosis: Summary statement of a First National Institutes of Health/Office of Rare Diseases conference

The Journal of pediatrics, 2006-08, Vol.149 (2), p.159-164

2006

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Transport, cilia, and PKD: must we in (cyst) on interrelationships? Focus on “Increased Na + /H + exchanger activity on the apical surface of a cilium-deficient cortical collecting duct principal cell model of polycystic kidney disease”

American Journal of Physiology: Cell Physiology, 2012-05, Vol.302 (10), p.C1434-C1435, Article C1434

2012

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Chronic blockade of 20-HETE synthesis reduces polycystic kidney disease in an orthologous rat model of ARPKD

American journal of physiology. Renal physiology, 2009-03, Vol.296 (3), p.F575-F582

2009

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Birth of a healthy infant following preimplantation PKHD1 haplotyping for autosomal recessive polycystic kidney disease using multiple displacement amplification

Journal of assisted reproduction and genetics, 2010-07, Vol.27 (7), p.397-407

2010

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Polycystin-1 Distribution Is Modulated by Polycystin-2 Expression in Mammalian Cells

The Journal of biological chemistry, 2003-09, Vol.278 (38), p.36786-36793

2003

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EGF-related growth factors in the pathogenesis of murine ARPKD

Kidney international, 2004-06, Vol.65 (6), p.2018-2029

2004

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Epidermal growth factor receptor tyrosine kinase inhibition is not protective in PCK rats

Kidney international, 2004-11, Vol.66 (5), p.1766-1773

2004

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Milder presentation of recessive polycystic kidney disease requires presence of amino acid substitution mutations

Journal of the American Society of Nephrology, 2003-08, Vol.14 (8), p.2004-2014

2003

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Pediatric Nephrology

Seventh edition, 2015

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HDAC6 regulates epidermal growth factor receptor (EGFR) endocytic trafficking and degradation in renal epithelial cells

Sirtuin 1 inhibition delays cyst formation in autosomal-dominant polycystic kidney disease

New approaches to the autosomal recessive polycystic kidney disease patient with dual kidney-liver complications

Src Inhibition Ameliorates Polycystic Kidney Disease

Pathophysiology of childhood polycystic kidney diseases: new insights into disease-specific therapy

Diagnosis and management of childhood polycystic kidney disease

Molecular and cellular pathophysiology of autosomal recessive polycystic kidney disease (ARPKD)

Smac-Mimetic―Induced Epithelial Cell Death Reduces the Growth of Renal Cysts

PKHD1, the Polycystic Kidney and Hepatic Disease 1 Gene, Encodes a Novel Large Protein Containing Multiple Immunoglobulin-Like Plexin-Transcription–Factor Domains and Parallel Beta-Helix 1 Repeats

Loss of activator of G‐protein signaling 3 impairs renal tubular regeneration following acute kidney injury in rodents

G-protein signaling modulator 1 deficiency accelerates cystic disease in an orthologous mouse model of autosomal dominant polycystic kidney disease

20-HETE Mediates Proliferation of Renal Epithelial Cells in Polycystic Kidney Disease

20-HETE activates the Raf/MEK/ERK pathway in renal epithelial cells through an EGFR- and c-Src-dependent mechanism

EGF receptor tyrosine kinase inhibition attenuates the development of PKD in Han:SPRD rats

Role of genetic modifiers in an orthologous rat model of ARPKD

Emerging Therapies for Childhood Polycystic Kidney Disease

Autosomal recessive polycystic kidney disease and congenital hepatic fibrosis: Summary statement of a First National Institutes of Health/Office of Rare Diseases conference

Transport, cilia, and PKD: must we in (cyst) on interrelationships? Focus on “Increased Na + /H + exchanger activity on the apical surface of a cilium-deficient cortical collecting duct principal cell model of polycystic kidney disease”

Chronic blockade of 20-HETE synthesis reduces polycystic kidney disease in an orthologous rat model of ARPKD

Birth of a healthy infant following preimplantation PKHD1 haplotyping for autosomal recessive polycystic kidney disease using multiple displacement amplification

Polycystin-1 Distribution Is Modulated by Polycystin-2 Expression in Mammalian Cells

EGF-related growth factors in the pathogenesis of murine ARPKD

Epidermal growth factor receptor tyrosine kinase inhibition is not protective in PCK rats

Milder presentation of recessive polycystic kidney disease requires presence of amino acid substitution mutations

Pediatric Nephrology

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