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Hypoxia tolerance, longevity and cancer-resistance in the mole rat Spalax - a liver transcriptomics approach

Scientific reports, 2017-10, Vol.7 (1), p.14348-13, Article 14348

2017

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Senescent Secretome of Blind Mole Rat Spalax Inhibits Malignant Behavior of Human Breast Cancer Cells Triggering Bystander Senescence and Targeting Inflammatory Response

International journal of molecular sciences, 2023-03, Vol.24 (6), p.5132

2023

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Neuroglobin, cytoglobin, and myoglobin contribute to hypoxia adaptation of the subterranean mole rat Spalax

Proceedings of the National Academy of Sciences - PNAS, 2010-12, Vol.107 (50), p.21570-21575

2010

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The transcriptome landscape of the carcinogenic treatment response in the blind mole rat: insights into cancer resistance mechanisms

BMC genomics, 2019-01, Vol.20 (1), p.17-17, Article 17

2019

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Hypoxic Stress Tolerance of the Blind Subterranean Mole Rat: Expression of Erythropoietin and Hypoxia-Inducible Factor 1α

Proceedings of the National Academy of Sciences - PNAS, 2004-06, Vol.101 (26), p.9698-9703

2004

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Transcriptome analysis of the spalax hypoxia survival response includes suppression of apoptosis and tight control of angiogenesis

BMC genomics, 2012-11, Vol.13 (1), p.615-615, Article 615

2012

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Cytoglobin Is a Respiratory Protein in Connective Tissue and Neurons, Which Is Up-regulated by Hypoxia

The Journal of biological chemistry, 2004-02, Vol.279 (9), p.8063-8069

2004

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The expression of p53-target genes in the hypoxia-tolerant subterranean mole-rat is hypoxia-dependent and similar to expression patterns in solid tumors

Cell cycle (Georgetown, Tex.), 2010-08, Vol.9 (16), p.3367-3372

2010

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Alternatively Spliced Spalax Heparanase Inhibits Extracellular Matrix Degradation, Tumor Growth, and Metastasis

Proceedings of the National Academy of Sciences - PNAS, 2009-02, Vol.106 (7), p.2253-2258

2009

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Transcriptome sequencing of the blind subterranean mole rat, Spalax galili: utility and potential for the discovery of novel evolutionary patterns

PloS one, 2011-08, Vol.6 (8), p.e21227

2011

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Evolution of p53 in Hypoxia-Stressed Spalax Mimics Human Tumor Mutation

Proceedings of the National Academy of Sciences - PNAS, 2004-08, Vol.101 (33), p.12236-12241

2004

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Ontogenetic expression of erythropoietin and hypoxia-inducible factor-1 alpha genes in subterranean blind mole rats

The FASEB journal, 2005-02, Vol.19 (2), p.307-309

2005

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Splice Variant of Spalax Heparanase Skipping Exon 12

Genes, 2024-08, Vol.15 (8), p.1039

2024

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A Mouse Model for Achondroplasia Produced by Targeting Fibroblast Growth Factor Receptor 3

Proceedings of the National Academy of Sciences - PNAS, 1999-04, Vol.96 (8), p.4455-4460

1999

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nemy encodes a cytochrome b561 that is required for Drosophila learning and memory

Proceedings of the National Academy of Sciences - PNAS, 2008-12, Vol.105 (50), p.19986-19991

2008

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Pronounced cancer resistance in a subterranean rodent, the blind mole-rat, Spalax: in vivo and in vitroevidence

BMC biology, 2013-08, Vol.11 (1), Article 91

2013

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Adaptive Evolution of Heparanase in Hypoxia-Tolerant Spalax: Gene Cloning and Identification of a Unique Splice Variant

Proceedings of the National Academy of Sciences - PNAS, 2005-10, Vol.102 (42), p.15161-15166

2005

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An Extracellular Region of the Erythropoietin Receptor of the Subterranean Blind Mole Rat Spalax Enhances Receptor Maturation

Proceedings of the National Academy of Sciences - PNAS, 2007-09, Vol.104 (36), p.14360-14365

2007

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Senescent Secretome of Blind Mole Rat ISpalax/I Inhibits Malignant Behavior of Human Breast Cancer Cells Triggering Bystander Senescence and Targeting Inflammatory Response

International journal of molecular sciences, 2023-03, Vol.24 (6)

2023

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Molecular evolution of antioxidant and hypoxia response in long-lived, cancer-resistant blind mole rats: The Nrf2–Keap1 pathway

Gene, 2016-02, Vol.577 (2), p.293-298

2016

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Hypoxia-induced BNIP3 expression and mitophagy: in vivo comparison of the rat and the hypoxia-tolerant mole rat, Spalax ehrenbergi

The FASEB journal, 2009-07, Vol.23 (7), p.2327-2335

2009

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Circadian Genes in a Blind Subterranean Mammal II: Conservation and Uniqueness of the Three Period Homologs in the Blind Subterranean Mole Rat, Spalax ehrenbergi Superspecies

Proceedings of the National Academy of Sciences - PNAS, 2002-09, Vol.99 (18), p.11718-11723

2002

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Mammalian microevolution in action: adaptive edaphic genomic divergence in blind subterranean mole–rats

Proceedings of the Royal Society. B, Biological sciences, 2004-05, Vol.271 (Suppl 4), p.S156-S159

2004

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Non-image Forming Light Detection by Melanopsin, Rhodopsin, and Long-Middlewave (L/W) Cone Opsin in the Subterranean Blind Mole Rat, Spalax Ehrenbergi: Immunohistochemical Characterization, Distribution, and Connectivity

Frontiers in neuroanatomy, 2016-06, Vol.10, p.61-61

2016

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p53: A Key Player in Tumoral and Evolutionary Adaptation: A Lesson from the Israeli Blind Subterranean Mole Rat

Cell cycle (Georgetown, Tex.), 2005-03, Vol.4 (3), p.368-372

2005

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Hypoxia tolerance, longevity and cancer-resistance in the mole rat Spalax - a liver transcriptomics approach

Senescent Secretome of Blind Mole Rat Spalax Inhibits Malignant Behavior of Human Breast Cancer Cells Triggering Bystander Senescence and Targeting Inflammatory Response

Neuroglobin, cytoglobin, and myoglobin contribute to hypoxia adaptation of the subterranean mole rat Spalax

The transcriptome landscape of the carcinogenic treatment response in the blind mole rat: insights into cancer resistance mechanisms

Hypoxic Stress Tolerance of the Blind Subterranean Mole Rat: Expression of Erythropoietin and Hypoxia-Inducible Factor 1α

Transcriptome analysis of the spalax hypoxia survival response includes suppression of apoptosis and tight control of angiogenesis

Cytoglobin Is a Respiratory Protein in Connective Tissue and Neurons, Which Is Up-regulated by Hypoxia

The expression of p53-target genes in the hypoxia-tolerant subterranean mole-rat is hypoxia-dependent and similar to expression patterns in solid tumors

Alternatively Spliced Spalax Heparanase Inhibits Extracellular Matrix Degradation, Tumor Growth, and Metastasis

Transcriptome sequencing of the blind subterranean mole rat, Spalax galili: utility and potential for the discovery of novel evolutionary patterns

Evolution of p53 in Hypoxia-Stressed Spalax Mimics Human Tumor Mutation

Ontogenetic expression of erythropoietin and hypoxia-inducible factor-1 alpha genes in subterranean blind mole rats

Splice Variant of Spalax Heparanase Skipping Exon 12

A Mouse Model for Achondroplasia Produced by Targeting Fibroblast Growth Factor Receptor 3

nemy encodes a cytochrome b561 that is required for Drosophila learning and memory

Pronounced cancer resistance in a subterranean rodent, the blind mole-rat, Spalax: in vivo and in vitroevidence

Adaptive Evolution of Heparanase in Hypoxia-Tolerant Spalax: Gene Cloning and Identification of a Unique Splice Variant

An Extracellular Region of the Erythropoietin Receptor of the Subterranean Blind Mole Rat Spalax Enhances Receptor Maturation

Senescent Secretome of Blind Mole Rat ISpalax/I Inhibits Malignant Behavior of Human Breast Cancer Cells Triggering Bystander Senescence and Targeting Inflammatory Response

Molecular evolution of antioxidant and hypoxia response in long-lived, cancer-resistant blind mole rats: The Nrf2–Keap1 pathway

Hypoxia-induced BNIP3 expression and mitophagy: in vivo comparison of the rat and the hypoxia-tolerant mole rat, Spalax ehrenbergi

Circadian Genes in a Blind Subterranean Mammal II: Conservation and Uniqueness of the Three Period Homologs in the Blind Subterranean Mole Rat, Spalax ehrenbergi Superspecies

Mammalian microevolution in action: adaptive edaphic genomic divergence in blind subterranean mole–rats

Non-image Forming Light Detection by Melanopsin, Rhodopsin, and Long-Middlewave (L/W) Cone Opsin in the Subterranean Blind Mole Rat, Spalax Ehrenbergi: Immunohistochemical Characterization, Distribution, and Connectivity

p53: A Key Player in Tumoral and Evolutionary Adaptation: A Lesson from the Israeli Blind Subterranean Mole Rat

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