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Nucleic Acids Chemistry: Modifications and Conjugates for Biomedicine and Nanotechnology

Eritja, Ramon

1, 2021

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G-quadruplex binding properties of a potent PARP-1 inhibitor derived from 7-azaindole-1-carboxamide

Scientific reports, 2021-02, Vol.11 (1), p.3869-3869, Article 3869

2021

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Stabilization of c-KIT G-Quadruplex DNA Structures by the RNA Polymerase I Inhibitors BMH-21 and BA-41

International journal of molecular sciences, 2019-10, Vol.20 (19), p.4927

2019

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Quadruplex-duplex junction in LTR-III: A molecular insight into the complexes with BMH-21, namitecan and doxorubicin

PloS one, 2024-07, Vol.19 (7), p.e0306239

2024

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Selective depletion of metastatic stem cells as therapy for human colorectal cancer

EMBO molecular medicine, 2018-10, Vol.10 (10), p.n/a

2018

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Detection of SARS-CoV-2 Virus by Triplex Enhanced Nucleic Acid Detection Assay (TENADA)

International journal of molecular sciences, 2022-12, Vol.23 (23), p.15258

2022

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Exploring PAZ/3'-overhang interaction to improve siRNA specificity. A combined experimental and modeling study

Chemical science (Cambridge), 2018, Vol.9 (8), p.2074-2086

2018

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Effects of Sugar Functional Groups, Hydrophobicity, and Fluorination on Carbohydrate–DNA Stacking Interactions in Water

Journal of organic chemistry, 2014-03, Vol.79 (6), p.2419-2429

2014

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The gene silencing of IRF5 and BLYSS effectively modulates the outcome of experimental lupus nephritis

Molecular therapy. Nucleic acids, 2021-06, Vol.24, p.807-821

2021

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Detection of a G-Quadruplex as a Regulatory Element in Thymidylate synthase for Gene Silencing Using Polypurine Reverse Hoogsteen Hairpins

International journal of molecular sciences, 2020-07, Vol.21 (14), p.5028

2020

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Evaluation of Poly( N -Ethyl Pyrrolidine Methacrylamide) (EPA) and Derivatives as Polymeric Vehicles for miRNA Delivery to Neural Cells

Pharmaceutics, 2023-05, Vol.15 (5), p.1451

2023

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Controlling the Reversible Assembly of Liposomes through a Multistimuli Responsive Anchored DNA

Nano letters, 2016-07, Vol.16 (7), p.4462-4466

2016

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Fast and Accurate Pneumocystis Pneumonia Diagnosis in Human Samples Using a Label-Free Plasmonic Biosensor

Nanomaterials (Basel, Switzerland), 2020-06, Vol.10 (6), p.1246

2020

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Triplex Hybridization-Based Nanosystem for the Rapid Screening of Pneumocystis Pneumonia in Clinical Samples

Journal of fungi (Basel), 2020-11, Vol.6 (4), p.292

2020

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A pH-dependent bolt involving cytosine bases located in the lateral loops of antiparallel G-quadruplex structures within the SMARCA4 gene promotor

Scientific reports, 2019-11, Vol.9 (1), p.15807-16, Article 15807

2019

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Oligonucleotides Carrying Nucleoside Antimetabolites as Potential Prodrugs

Current medicinal chemistry, 2023-01, Vol.30 (11), p.1304

2023

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Chemical Modifications in Nucleic Acids for Therapeutic and Diagnostic Applications

Chemical record, 2022-04, Vol.22 (4), p.e202100270-n/a

2022

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Thrombin binding aptamer, more than a simple aptamer: chemically modified derivatives and biomedical applications

Current pharmaceutical design, 2012-05, Vol.18 (14), p.2036

2012

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Aptamer-Drug conjugates for a targeted and synergistic anticancer Response: Exploiting T30923-5-fluoro-2′-deoxyuridine (INT-FdU) derivatives

European journal of pharmaceutics and biopharmaceutics, 2024-08, Vol.201, p.114354, Article 114354

2024

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Evaluation of Floxuridine Oligonucleotide Conjugates Carrying Potential Enhancers of Cellular Uptake

International journal of molecular sciences, 2021-05, Vol.22 (11), p.5678

2021

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The Origins and the Biological Consequences of the Pur/Pyr DNA·RNA Asymmetry

Chem, 2019-06, Vol.5 (6), p.1619-1631

2019

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Exploring the Interaction of G-quadruplex Binders with a (3 + 1) Hybrid G-quadruplex Forming Sequence within the PARP1 Gene Promoter Region

Molecules (Basel, Switzerland), 2022-07, Vol.27 (15), p.4792

2022

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Study of conformational transitions of i-motif DNA using time-resolved fluorescence and multivariate analysis methods

Nucleic acids research, 2019-07, Vol.47 (13), p.6590

2019

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An aptamer-gated silica mesoporous material for thrombin detection

Chemical communications (Cambridge, England), 2013-01, Vol.49 (48), p.5480-5482

2013

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Exploring the stabilizing effect on the i-motif of neighboring structural motifs and drugs

International journal of biological macromolecules, 2023-07, Vol.242 (Pt 2), p.124794-124794, Article 124794

2023

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Nucleic Acids Chemistry: Modifications and Conjugates for Biomedicine and Nanotechnology

G-quadruplex binding properties of a potent PARP-1 inhibitor derived from 7-azaindole-1-carboxamide

Stabilization of c-KIT G-Quadruplex DNA Structures by the RNA Polymerase I Inhibitors BMH-21 and BA-41

Quadruplex-duplex junction in LTR-III: A molecular insight into the complexes with BMH-21, namitecan and doxorubicin

Selective depletion of metastatic stem cells as therapy for human colorectal cancer

Detection of SARS-CoV-2 Virus by Triplex Enhanced Nucleic Acid Detection Assay (TENADA)

Exploring PAZ/3'-overhang interaction to improve siRNA specificity. A combined experimental and modeling study

Effects of Sugar Functional Groups, Hydrophobicity, and Fluorination on Carbohydrate–DNA Stacking Interactions in Water

The gene silencing of IRF5 and BLYSS effectively modulates the outcome of experimental lupus nephritis

Detection of a G-Quadruplex as a Regulatory Element in Thymidylate synthase for Gene Silencing Using Polypurine Reverse Hoogsteen Hairpins

Evaluation of Poly( N -Ethyl Pyrrolidine Methacrylamide) (EPA) and Derivatives as Polymeric Vehicles for miRNA Delivery to Neural Cells

Controlling the Reversible Assembly of Liposomes through a Multistimuli Responsive Anchored DNA

Fast and Accurate Pneumocystis Pneumonia Diagnosis in Human Samples Using a Label-Free Plasmonic Biosensor

Triplex Hybridization-Based Nanosystem for the Rapid Screening of Pneumocystis Pneumonia in Clinical Samples

A pH-dependent bolt involving cytosine bases located in the lateral loops of antiparallel G-quadruplex structures within the SMARCA4 gene promotor

Oligonucleotides Carrying Nucleoside Antimetabolites as Potential Prodrugs

Chemical Modifications in Nucleic Acids for Therapeutic and Diagnostic Applications

Thrombin binding aptamer, more than a simple aptamer: chemically modified derivatives and biomedical applications

Aptamer-Drug conjugates for a targeted and synergistic anticancer Response: Exploiting T30923-5-fluoro-2′-deoxyuridine (INT-FdU) derivatives

Evaluation of Floxuridine Oligonucleotide Conjugates Carrying Potential Enhancers of Cellular Uptake

The Origins and the Biological Consequences of the Pur/Pyr DNA·RNA Asymmetry

Exploring the Interaction of G-quadruplex Binders with a (3 + 1) Hybrid G-quadruplex Forming Sequence within the PARP1 Gene Promoter Region

Study of conformational transitions of i-motif DNA using time-resolved fluorescence and multivariate analysis methods

An aptamer-gated silica mesoporous material for thrombin detection

Exploring the stabilizing effect on the i-motif of neighboring structural motifs and drugs

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