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Physicochemical Characterization of Berberine Chloride: A Perspective in the Development of a Solution Dosage Form for Oral Delivery

AAPS PharmSciTech, 2010-09, Vol.11 (3), p.1466-1475

2010

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Structure–Activity Relationships of the Antimalarial Agent Artemisinin 10. Synthesis and Antimalarial Activity of Enantiomers of rac-5β-Hydroxy-d-Secoartemisinin and Analogs: Implications Regarding the Mechanism of Action

Molecules (Basel, Switzerland), 2021-07, Vol.26 (14), p.4163

2021

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Antimalarial Artemisinin Drugs Induce Cytochrome P450 and MDR1 Expression by Activation of Xenosensors Pregnane X Receptor and Constitutive Androstane Receptor

Molecular pharmacology, 2005-06, Vol.67 (6), p.1954-1965

2005

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Computer-Aided Drug Design of Falcipain Inhibitors: Virtual Screening, Structure–Activity Relationships, Hydration Site Thermodynamics, and Reactivity Analysis

Journal of chemical information and modeling, 2012-03, Vol.52 (3), p.696-710

2012

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Expression in Yeast Links Field Polymorphisms in PfATP6 to in Vitro Artemisinin Resistance and Identifies New Inhibitor Classes

The Journal of infectious diseases, 2013-08, Vol.208 (3), p.468-478

2013

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Nigellidine-4-O-sulfite, the First Sulfated Indazole-Type Alkaloid from the Seeds of Nigella sativa

Journal of natural products (Washington, D.C.), 2008-06, Vol.71 (6), p.1111-1112

2008

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Structure-based design of novel melanin-concentrating hormone receptor-1 ligands based on saturated nitrogen-containing heterocycles

Bioorganic & medicinal chemistry letters, 2023-03, Vol.84, p.129194-129194, Article 129194

2023

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Biochemical properties of a novel cysteine protease of Plasmodium vivax, vivapain-4

PLoS neglected tropical diseases, 2010-10, Vol.4 (10), p.e849

2010

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Selective Inhibition of Plasmodium falciparum ATPase 6 by Artemisinins and Identification of New Classes of Inhibitors after Expression in Yeast

Antimicrobial agents and chemotherapy, 2022-05, Vol.66 (5), p.e0207921-e0207921

2022

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Structure−Activity Relationships of the Antimalarial Agent Artemisinin. 8. Design, Synthesis, and CoMFA Studies toward the Development of Artemisinin-Based Drugs against Leishmaniasis and Malaria

Journal of medicinal chemistry, 2003-09, Vol.46 (20), p.4244-4258

2003

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Computationally Assisted Discovery and Assignment of a Highly Strained and PANC‑1 Selective Alkaloid from Alaska’s Deep Ocean

Journal of the American Chemical Society, 2019-03, Vol.141 (10), p.4338-4344

2019

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Ultra-performance liquid chromatography–tandem mass spectrometric method for the determination of Artemisinin in rat serum and its application in pharmacokinetics

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008-05, Vol.867 (1), p.131-137

2008

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Identification of a new small molecule chemotype of Melanin Concentrating Hormone Receptor-1 antagonists using pharmacophore-based virtual screening

Bioorganic & medicinal chemistry letters, 2019-12, Vol.29 (24), p.126741-126741, Article 126741

2019

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Isolation and Synthesis of Veranamine, an Antidepressant Lead from the Marine Sponge Verongula rigida

Journal of natural products (Washington, D.C.), 2020-04, Vol.83 (4), p.1092-1098

2020

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Identification of Telmisartan as a Unique Angiotensin II: Receptor Antagonist With Selective PPARγ–Modulating Activity

Hypertension (Dallas, Tex. 1979), 2004-05, Vol.43 (5), p.993-1002

2004

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Analysis of CoQ10 in rat serum by ultra-performance liquid chromatography mass spectrometry after oral administration

Journal of pharmaceutical and biomedical analysis, 2008-01, Vol.46 (1), p.137-142

2008

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1,3-Diaxially Substituted trans-Decalins: Potential Nonsteroidal Human Progesterone Receptor Inhibitors

Journal of organic chemistry, 2008-10, Vol.73 (19), p.7764-7767

2008

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Structure-based approach to falcipain-2 inhibitors: synthesis and biological evaluation of 1,6,7-Trisubstituted dihydroisoquinolines and isoquinolines

Bioorganic & medicinal chemistry, 2003-05, Vol.11 (10), p.2293-2299

2003

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Progress in the development of peroxide-based anti-parasitic agents

Drug discovery today, 2009-08, Vol.14 (15), p.793-803

2009

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Identification of Novel Malarial Cysteine Protease Inhibitors Using Structure-Based Virtual Screening of a Focused Cysteine Protease Inhibitor Library

Journal of chemical information and modeling, 2011-04, Vol.51 (4), p.852-864

2011

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Synthesis and Cyclization Reaction of Pyrazolin-5-one Derivatives

Heterocycles, 2005, Vol.65 (1), p.77

2005

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Type 2 diabetes and oral antihyperglycemic drugs

Current medicinal chemistry, 2008, Vol.15 (1), p.61-74

2008

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Microbial and Chemical Transformation Studies of the Bioactive Marine Sesquiterpenes (S)-(+)-Curcuphenol and -Curcudiol Isolated from a Deep Reef Collection of the Jamaican Sponge Didiscus oxeata

Journal of natural products (Washington, D.C.), 2002-11, Vol.65 (11), p.1547-1553

2002

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Epothilone B inhibits neointimal formation after rat carotid injury through the regulation of cell cycle-related proteins

The Journal of pharmacology and experimental therapeutics, 2007-05, Vol.321 (2), p.648-655

2007

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Carrier-Mediated Partitioning of Artemisinin into Plasmodium falciparum-Infected Erythrocytes

Antimicrobial Agents and Chemotherapy, 2002-01, Vol.46 (1), p.105-109

2002

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Physicochemical Characterization of Berberine Chloride: A Perspective in the Development of a Solution Dosage Form for Oral Delivery

Structure–Activity Relationships of the Antimalarial Agent Artemisinin 10. Synthesis and Antimalarial Activity of Enantiomers of rac-5β-Hydroxy-d-Secoartemisinin and Analogs: Implications Regarding the Mechanism of Action

Antimalarial Artemisinin Drugs Induce Cytochrome P450 and MDR1 Expression by Activation of Xenosensors Pregnane X Receptor and Constitutive Androstane Receptor

Computer-Aided Drug Design of Falcipain Inhibitors: Virtual Screening, Structure–Activity Relationships, Hydration Site Thermodynamics, and Reactivity Analysis

Expression in Yeast Links Field Polymorphisms in PfATP6 to in Vitro Artemisinin Resistance and Identifies New Inhibitor Classes

Nigellidine-4-O-sulfite, the First Sulfated Indazole-Type Alkaloid from the Seeds of Nigella sativa

Structure-based design of novel melanin-concentrating hormone receptor-1 ligands based on saturated nitrogen-containing heterocycles

Biochemical properties of a novel cysteine protease of Plasmodium vivax, vivapain-4

Selective Inhibition of Plasmodium falciparum ATPase 6 by Artemisinins and Identification of New Classes of Inhibitors after Expression in Yeast

Structure−Activity Relationships of the Antimalarial Agent Artemisinin. 8. Design, Synthesis, and CoMFA Studies toward the Development of Artemisinin-Based Drugs against Leishmaniasis and Malaria

Computationally Assisted Discovery and Assignment of a Highly Strained and PANC‑1 Selective Alkaloid from Alaska’s Deep Ocean

Ultra-performance liquid chromatography–tandem mass spectrometric method for the determination of Artemisinin in rat serum and its application in pharmacokinetics

Identification of a new small molecule chemotype of Melanin Concentrating Hormone Receptor-1 antagonists using pharmacophore-based virtual screening

Isolation and Synthesis of Veranamine, an Antidepressant Lead from the Marine Sponge Verongula rigida

Identification of Telmisartan as a Unique Angiotensin II: Receptor Antagonist With Selective PPARγ–Modulating Activity

Analysis of CoQ10 in rat serum by ultra-performance liquid chromatography mass spectrometry after oral administration

1,3-Diaxially Substituted trans-Decalins: Potential Nonsteroidal Human Progesterone Receptor Inhibitors

Structure-based approach to falcipain-2 inhibitors: synthesis and biological evaluation of 1,6,7-Trisubstituted dihydroisoquinolines and isoquinolines

Progress in the development of peroxide-based anti-parasitic agents

Identification of Novel Malarial Cysteine Protease Inhibitors Using Structure-Based Virtual Screening of a Focused Cysteine Protease Inhibitor Library

Synthesis and Cyclization Reaction of Pyrazolin-5-one Derivatives

Type 2 diabetes and oral antihyperglycemic drugs

Microbial and Chemical Transformation Studies of the Bioactive Marine Sesquiterpenes (S)-(+)-Curcuphenol and -Curcudiol Isolated from a Deep Reef Collection of the Jamaican Sponge Didiscus oxeata

Epothilone B inhibits neointimal formation after rat carotid injury through the regulation of cell cycle-related proteins

Carrier-Mediated Partitioning of Artemisinin into Plasmodium falciparum-Infected Erythrocytes

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