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Lessons From Pediatric MDS: Approaches to Germline Predisposition to Hematologic Malignancies

Frontiers in oncology, 2022-03, Vol.12, p.813149-813149

2022

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Editorial: Biological aspects of bone marrow failure

Frontiers in oncology, 2023-10, Vol.13, p.1295823-1295823

2023

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ATP-Binding Cassette Transporters and HDL Suppress Hematopoietic Stem Cell Proliferation

Science (American Association for the Advancement of Science), 2010-06, Vol.328 (5986), p.1689-1693

2010

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Prdm16 is a physiologic regulator of hematopoietic stem cells

Blood, 2011-05, Vol.117 (19), p.5057-5066

2011

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Microenvironmental control of hematopoietic stem cell fate via CXCL8 and protein kinase C

Cell reports (Cambridge), 2023-05, Vol.42 (5), p.112528-112528, Article 112528

2023

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Clonal hematopoiesis and inflammation – the perpetual cycle

Trends in cell biology, 2023-08, Vol.33 (8), p.695-707

2023

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Quantitative trait mapping reveals a regulatory axis involving peroxisome proliferator-activated receptors, PRDM16, transforming growth factor-β2 and FLT3 in hematopoiesis

Blood, 2011-12, Vol.118 (23), p.6078-6086

2011

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Asxl1-mutant Dominant Clones Have an Erythropoietic Lineage Deficiency through a Disturbed Epigenetic Landscape

Blood, 2023-11, Vol.142 (Supplement 1), p.4063-4063

2023

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To T or not to B: germline RUNX1 mutation preferences in pediatric ALL predisposition

The Journal of clinical investigation, 2021-09, Vol.131 (17)

2021

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2023 – CELLULAR BARCODING OF THE LEUKEMIC NICHE REVEALS AN APELIN-MEDIATED CLONAL EXPANSION OF NICHE ENDOTHELIAL AND MESENCHYMAL STROMAL CELLS

Experimental hematology, 2023, Vol.124, p.S48

2023

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Fish to Learn: Insights into Blood Development and Blood Disorders from Zebrafish Hematopoiesis

Human gene therapy, 2016-04, Vol.27 (4), p.287-294

2016

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3009 – APELIN-MEDIATED CLONAL EXPANSION OF NICHE ENDOTHELIAL CELLS DRIVES SELECTION OF LEUKEMIC AND NORMAL HSC CLONES

Experimental hematology, 2024-08, Vol.137, p.104297, Article 104297

2024

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Effect of enforced expression of cxcl8 by hematopoietic stem and progenitor cells on niche interactions and hematopoietic progenitor cells in adult zebrafish

Journal of clinical oncology, 2018-05, Vol.36 (15_suppl), p.7070-7070

2018

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Visualizing Clonal Hematopoiesis Associated with gata2 Deficiency in Zebrafish Using Color-Barcoding

Blood, 2017-12, Vol.130, p.4237-4237

2017

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Early Clonal Hematopoiesis Detected in Gata2 heterozygosity By Color-Barcoding of Hematopoietic Stem Cells in Zebrafish

Blood, 2018-11, Vol.132 (Supplement 1), p.748-748

2018

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Loss of nr4a1 abrogates Fitness of asxl1-mutant Hematopoietic Clones

Blood, 2021-11, Vol.138 (Supplement 1), p.3272-3272

2021

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Understanding the regulation of vertebrate hematopoiesis and blood disorders – big lessons from a small fish

FEBS letters, 2016-11, Vol.590 (22), p.4016-4033

2016

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P23-031-23 Inhibition of Choline-Phospholipid Metabolism Prevents Clonal Hematopoiesis Progression

Current developments in nutrition, 2023-07, Vol.7, p.100143, Article 100143

2023

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Mosaic Mutagenesis In Vivo Reveals Mutant Blood Stem Cells Intrinsically Resistant to Inflammatory Mediators in Clonal Hematopoiesis

Blood, 2020-11, Vol.136 (Supplement 1), p.27-27

2020

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Cxcl8 Expands Hematopoietic Stem and Progenitor Cells and Alters Their Interaction with the Endothelial Niche

Blood, 2019-11, Vol.134 (Supplement_1), p.527-527

2019

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Cxcl8/PKC Signaling in the Endothelial Cell Niche Regulates Long-Term Hematopoietic Stem Cell Fate

Blood, 2020-11, Vol.136 (Supplement 1), p.38-38

2020

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Abstract PR01: Modeling clonal hematopoietic disorders in zebrafish using combinatorial mutagenesis and color barcoding

Clinical cancer research, 2017-12, Vol.23 (24_Supplement), p.PR01-PR01

2017

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Abstract A27: Cellular barcoding of the leukemic niche reveals an apelin-mediated clonal expansion of niche endothelial and mesenchymal stromal cell clones

Blood cancer discovery, 2023-05, Vol.4 (3_Supplement), p.A27-A27

2023

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Outcomes of Allogeneic Stem Cell Transplantation in Pediatric Patients with Myelodysplastic Syndrome and Bone Marrow Failure Due to GATA2 Haploinsufficiency: A Case Control Study

Blood, 2016-12, Vol.128 (22), p.4686-4686

2016

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Modeling Clonal Hematopoietic Disorders in Zebrafish Using Color Barcoding

Blood, 2016-12, Vol.128 (22), p.3147-3147

2016

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Lessons From Pediatric MDS: Approaches to Germline Predisposition to Hematologic Malignancies

Editorial: Biological aspects of bone marrow failure

ATP-Binding Cassette Transporters and HDL Suppress Hematopoietic Stem Cell Proliferation

Prdm16 is a physiologic regulator of hematopoietic stem cells

Microenvironmental control of hematopoietic stem cell fate via CXCL8 and protein kinase C

Clonal hematopoiesis and inflammation – the perpetual cycle

Quantitative trait mapping reveals a regulatory axis involving peroxisome proliferator-activated receptors, PRDM16, transforming growth factor-β2 and FLT3 in hematopoiesis

Asxl1-mutant Dominant Clones Have an Erythropoietic Lineage Deficiency through a Disturbed Epigenetic Landscape

To T or not to B: germline RUNX1 mutation preferences in pediatric ALL predisposition

2023 – CELLULAR BARCODING OF THE LEUKEMIC NICHE REVEALS AN APELIN-MEDIATED CLONAL EXPANSION OF NICHE ENDOTHELIAL AND MESENCHYMAL STROMAL CELLS

Fish to Learn: Insights into Blood Development and Blood Disorders from Zebrafish Hematopoiesis

3009 – APELIN-MEDIATED CLONAL EXPANSION OF NICHE ENDOTHELIAL CELLS DRIVES SELECTION OF LEUKEMIC AND NORMAL HSC CLONES

Effect of enforced expression of cxcl8 by hematopoietic stem and progenitor cells on niche interactions and hematopoietic progenitor cells in adult zebrafish

Visualizing Clonal Hematopoiesis Associated with gata2 Deficiency in Zebrafish Using Color-Barcoding

Early Clonal Hematopoiesis Detected in Gata2 heterozygosity By Color-Barcoding of Hematopoietic Stem Cells in Zebrafish

Loss of nr4a1 abrogates Fitness of asxl1-mutant Hematopoietic Clones

Understanding the regulation of vertebrate hematopoiesis and blood disorders – big lessons from a small fish

P23-031-23 Inhibition of Choline-Phospholipid Metabolism Prevents Clonal Hematopoiesis Progression

Mosaic Mutagenesis In Vivo Reveals Mutant Blood Stem Cells Intrinsically Resistant to Inflammatory Mediators in Clonal Hematopoiesis

Cxcl8 Expands Hematopoietic Stem and Progenitor Cells and Alters Their Interaction with the Endothelial Niche

Cxcl8/PKC Signaling in the Endothelial Cell Niche Regulates Long-Term Hematopoietic Stem Cell Fate

Abstract PR01: Modeling clonal hematopoietic disorders in zebrafish using combinatorial mutagenesis and color barcoding

Abstract A27: Cellular barcoding of the leukemic niche reveals an apelin-mediated clonal expansion of niche endothelial and mesenchymal stromal cell clones

Outcomes of Allogeneic Stem Cell Transplantation in Pediatric Patients with Myelodysplastic Syndrome and Bone Marrow Failure Due to GATA2 Haploinsufficiency: A Case Control Study

Modeling Clonal Hematopoietic Disorders in Zebrafish Using Color Barcoding

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