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Improving potency and selectivity of a new class of non-Zn-chelating MMP-13 inhibitors

Bioorganic & medicinal chemistry letters, 2009-09, Vol.19 (18), p.5321-5324

2009

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Reversal of H3K9me2 by a Small-Molecule Inhibitor for the G9a Histone Methyltransferase

Molecular cell, 2007-02, Vol.25 (3), p.473-481

2007

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Benzimidazolone as potent chymase inhibitor: Modulation of reactive metabolite formation in the hydrophobic (P 1) region

Bioorganic & medicinal chemistry letters, 2011-08, Vol.21 (15), p.4533-4539

2011

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SAR studies of non-zinc-chelating MMP-13 inhibitors: Improving selectivity and metabolic stability

Bioorganic & medicinal chemistry letters, 2010-09, Vol.20 (17), p.5039-5043

2010

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Bioluminescent method for assaying multiple semicarbazide-sensitive amine oxidase (SSAO) family members in both 96- and 384-well formats

Journal of biomolecular screening, 2011-10, Vol.16 (9), p.1106-1111

2011

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Development of a high-throughput assay to measure histidine decarboxylase activity

Journal of biomolecular screening, 2006-10, Vol.11 (7), p.816-821

2006

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1-(2,3-Dideoxy-.beta.-D-glycero-pent-2-enofuranosyl)thymine. A highly potent and selective anti-HIV agent

Journal of medicinal chemistry, 1989-02, Vol.32 (2), p.461-466

1989

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Abstract 5590: Screening of pediatric and adult sarcoma cell lines reveals novel patterns of sensitivity toward approved oncology drugs and investigational agents

Cancer research (Chicago, Ill.), 2013-04, Vol.73 (8_Supplement), p.5590-5590

2013

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Abstract 4361: Target and drug discovery for recalcitrant, rare and neglected cancers

Cancer research (Chicago, Ill.), 2013-04, Vol.73 (8_Supplement), p.4361-4361

2013

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3'-Deoxythymidin-2'-ene permeation of human lymphocyte H9 cells by nonfacilitated diffusion

Molecular pharmacology, 1991-02, Vol.39 (2), p.246-249

1991

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Mechanism of Uptake of 3′‐Deoxythymidin‐2′‐ene (d4T) in Human Lymphocyte H9 Cellsa

Annals of the New York Academy of Sciences, 1990-12, Vol.616 (1), p.475-476

1990

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Cyclopentenyl uracil: An effective inhibitor of uridine salvage in vivo

Biochemical pharmacology, 1995-01, Vol.49 (2), p.203-207

1995

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Non-steroidal anti-inflammatory drugs and tumor progression: inhibition of fibroblast hyaluronic acid production by indomethacin and mefenamic acid

Cancer letters, 1994-07, Vol.82 (1), p.49-54

1994

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Initial studies on the cellular pharmacology of 3'-deoxythymidin-2'-ene (d4t): A potent and selective inhibitor of human immunodeficiency virus

Biochemical pharmacology, 1988-12, Vol.37 (23), p.4419-4422

1988

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Synthesis and antiviral activity of several 2,5'-anhydro analogs of 3'-azido-3'-deoxythymidine (AZT), 3'-azido-2',3'-dideoxyuridine (AZU), 3'-azido-2',3'-dideoxy-5-halouridines, and 3'-deoxythymidine against human immunodeficiency virus (HIV-1) and Rauscher-Murine leukemia virus (R-MuLV)

Journal of medicinal chemistry, 1989-08, Vol.32 (8), p.1891-1895

1989

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Inhibition of poly(adenosine diphosphate-ribose) polymerase by thymidine and thymidine analogues in L1210 cells and its relationship to the potentiation of the antitumor activity of 1,3-bis(2-chloroethyl)-1-nitrosourea but not of 3'-[3-(2-chloroethyl)-3-nitrosoureido]-3'-deoxythymidine

Cancer research (Chicago, Ill.), 1991-03, Vol.51 (6), p.1586-1590

1991

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Mechanism of Uptake of 3′-Deoxythymidin-2′-ene (d4T) in Human Lymphocyte H9 Cells

Annals of the New York Academy of Sciences, 1990-12, Vol.616 (1), p.475-476

1990

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Metabolism and mode of selective inhibition of human immunodeficiency virus replication by 3'-azido-2',3'-dideoxy-5-iodouridine and 3'-azido-2',3'-dideoxy-5-bromouridine

Biochemical pharmacology, 1993-01, Vol.45 (1), p.223-230

1993

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Effect of thymidine on uptake, DNA alkylation, and DNA repair in L1210 cells treated with 1,3-bis(2-chloroethyl)-1-nitrosourea or 3'-[3-(2-chloroethyl)-3-nitrosoureido]-3'-deoxythymidine

Cancer research (Chicago, Ill.), 1988-08, Vol.48 (15), p.4272-4275

1988

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Inhibition of fibroblast hyaluronic acid production by suramin

Oncology research, 1993, Vol.5 (10-11), p.415

1993

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Syntheses of [2-14C] 2,5′-anhydro-3′-azido-3′-deoxythymidine and [2-14C] 2,5′-anhydro-3′-azido-2′,3′-dideoxy-5-iodouridine: Inhibitors of human immunodeficiency virus (HIV-1)

Journal of labelled compounds & radiopharmaceuticals, 1991-12, Vol.29 (12), p.1315-1321

1991

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pplicability of a Multiresidue Method and High Performance Liquid Chromatography for Determining Quinomethionate in Apples and Oranges

Journal of the Association of Official Analytical Chemists, 1983-07, Vol.66 (4), p.1018-1022

1983

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Synthesis of [2-14C] 3′-deoxythymidin-2′ -ENE (d4T) and [5-125I] 3′ -azido-2′, 3′-dideoxy-5-iodouridine: Potent inhibitors of human immunodeficiency virus (HIV-1)

Journal of labelled compounds & radiopharmaceuticals, 1989-06, Vol.27 (6), p.669-674

1989

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Applicability of a carbamate insecticide multiresidue method for determining additional types of pesticides in fruits and vegetables

Journal of the Association of Official Analytical Chemists, 1983-03, Vol.66 (2), p.234-240

1983

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Somatic genomic changes in single Alzheimer's disease neurons

Nature (London), 2022-04, Vol.604 (7907), p.714-722

2022

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Improving potency and selectivity of a new class of non-Zn-chelating MMP-13 inhibitors

Reversal of H3K9me2 by a Small-Molecule Inhibitor for the G9a Histone Methyltransferase

Benzimidazolone as potent chymase inhibitor: Modulation of reactive metabolite formation in the hydrophobic (P 1) region

SAR studies of non-zinc-chelating MMP-13 inhibitors: Improving selectivity and metabolic stability

Bioluminescent method for assaying multiple semicarbazide-sensitive amine oxidase (SSAO) family members in both 96- and 384-well formats

Development of a high-throughput assay to measure histidine decarboxylase activity

1-(2,3-Dideoxy-.beta.-D-glycero-pent-2-enofuranosyl)thymine. A highly potent and selective anti-HIV agent

Abstract 5590: Screening of pediatric and adult sarcoma cell lines reveals novel patterns of sensitivity toward approved oncology drugs and investigational agents

Abstract 4361: Target and drug discovery for recalcitrant, rare and neglected cancers

3'-Deoxythymidin-2'-ene permeation of human lymphocyte H9 cells by nonfacilitated diffusion

Mechanism of Uptake of 3′‐Deoxythymidin‐2′‐ene (d4T) in Human Lymphocyte H9 Cellsa

Cyclopentenyl uracil: An effective inhibitor of uridine salvage in vivo

Non-steroidal anti-inflammatory drugs and tumor progression: inhibition of fibroblast hyaluronic acid production by indomethacin and mefenamic acid

Initial studies on the cellular pharmacology of 3'-deoxythymidin-2'-ene (d4t): A potent and selective inhibitor of human immunodeficiency virus

Synthesis and antiviral activity of several 2,5'-anhydro analogs of 3'-azido-3'-deoxythymidine (AZT), 3'-azido-2',3'-dideoxyuridine (AZU), 3'-azido-2',3'-dideoxy-5-halouridines, and 3'-deoxythymidine against human immunodeficiency virus (HIV-1) and Rauscher-Murine leukemia virus (R-MuLV)

Inhibition of poly(adenosine diphosphate-ribose) polymerase by thymidine and thymidine analogues in L1210 cells and its relationship to the potentiation of the antitumor activity of 1,3-bis(2-chloroethyl)-1-nitrosourea but not of 3'-[3-(2-chloroethyl)-3-nitrosoureido]-3'-deoxythymidine

Mechanism of Uptake of 3′-Deoxythymidin-2′-ene (d4T) in Human Lymphocyte H9 Cells

Metabolism and mode of selective inhibition of human immunodeficiency virus replication by 3'-azido-2',3'-dideoxy-5-iodouridine and 3'-azido-2',3'-dideoxy-5-bromouridine

Effect of thymidine on uptake, DNA alkylation, and DNA repair in L1210 cells treated with 1,3-bis(2-chloroethyl)-1-nitrosourea or 3'-[3-(2-chloroethyl)-3-nitrosoureido]-3'-deoxythymidine

Inhibition of fibroblast hyaluronic acid production by suramin

Syntheses of [2-14C] 2,5′-anhydro-3′-azido-3′-deoxythymidine and [2-14C] 2,5′-anhydro-3′-azido-2′,3′-dideoxy-5-iodouridine: Inhibitors of human immunodeficiency virus (HIV-1)

pplicability of a Multiresidue Method and High Performance Liquid Chromatography for Determining Quinomethionate in Apples and Oranges

Synthesis of [2-14C] 3′-deoxythymidin-2′ -ENE (d4T) and [5-125I] 3′ -azido-2′, 3′-dideoxy-5-iodouridine: Potent inhibitors of human immunodeficiency virus (HIV-1)

Applicability of a carbamate insecticide multiresidue method for determining additional types of pesticides in fruits and vegetables

Somatic genomic changes in single Alzheimer's disease neurons

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