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Landscape of stimulation-responsive chromatin across diverse human immune cells

Nature genetics, 2019-10, Vol.51 (10), p.1494-1505

2019

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Single-cell transcriptional profiling of human thymic stroma uncovers novel cellular heterogeneity in the thymic medulla

Nature communications, 2021-02, Vol.12 (1), p.1096-1096, Article 1096

2021

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Thymic tuft cells promote an IL-4-enriched medulla and shape thymocyte development

Nature (London), 2018-07, Vol.559 (7715), p.627-631

2018

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Generation of Functional Thymic Epithelium from Human Embryonic Stem Cells that Supports Host T Cell Development

Cell stem cell, 2013-08, Vol.13 (2), p.219-229

2013

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Stem cell-based multi-tissue platforms to model human autoimmune diabetes

Molecular metabolism (Germany), 2022-12, Vol.66, p.101610-101610, Article 101610

2022

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From type 1 diabetes biology to therapy: The Human Islet Research Network

Molecular metabolism (Germany), 2021-12, Vol.54, p.101283-101283, Article 101283

2021

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Mitigating Ischemic Injury of Stem Cell-Derived Insulin-Producing Cells after Transplant

Stem cell reports, 2017-09, Vol.9 (3), p.807-819

2017

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Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitro

The EMBO journal, 2015-07, Vol.34 (13), p.1759-1772

2015

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Selective deletion of human leukocyte antigens protects stem cell-derived islets from immune rejection

Cell reports (Cambridge), 2021-08, Vol.36 (7), p.109538, Article 109538

2021

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Nanoporous Immunoprotective Device for Stem-Cell-Derived β‑Cell Replacement Therapy

ACS nano, 2017-08, Vol.11 (8), p.7747-7757

2017

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Development of a scalable method to isolate subsets of stem cell-derived pancreatic islet cells

Stem cell reports, 2022-04, Vol.17 (4), p.979-992

2022

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Redox regulation of m6A methyltransferase METTL3 in β-cells controls the innate immune response in type 1 diabetes

Nature cell biology, 2024-03, Vol.26 (3), p.421-437

2024

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Modeling human T1D-associated autoimmune processes

Molecular metabolism (Germany), 2022-02, Vol.56, p.101417, Article 101417

2022

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High-resolution epitope mapping of anti-Hu and anti-Yo autoimmunity by programmable phage display

Brain communications, 2020-01, Vol.2 (2), p.fcaa059-fcaa059

2020

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Ikaros is a principal regulator of Aire + mTEC homeostasis, thymic mimetic cell diversity, and central tolerance

Science immunology, 2023-10, Vol.8 (88), p.eabq3109

2023

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Low MOG Expression in Human Thymus, Implications for Central Tolerance Mechanisms in Autoimmunity Against MOG (P9-14.001)

Neurology, 2024-04, Vol.102 (17_supplement_1)

2024

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Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency

Nature (London), 2023-11, Vol.623 (7988), p.803-813

2023

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Impaired thymic AIRE expression underlies autoantibodies against type I IFNs in humans with inborn errors of the alternative NF-κB pathway

Clinical immunology (Orlando, Fla.), 2023-05, Vol.250, p.109369-109369, Article 109369

2023

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Supporting Survival of Transplanted Stem‐Cell‐Derived Insulin‐Producing Cells in an Encapsulation Device Augmented with Controlled Release of Amino Acids

Advanced biosystems, 2019-09, Vol.3 (9), p.n/a

2019

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Modeling human T1D-associated autoimmune processesBox 1. Potential applications of models to understand the immune processes leading to human T1D.Box 2. Potential applications of models to evaluate treatments for human T1D

Molecular metabolism (Germany), 2022-02, Vol.56, p.101417

2022

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Thymic tuft cells promote an IL4-enriched medulla and shape thymocyte development

Nature (London), 2018-07, Vol.559 (7715), p.627-631

2018

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Redox regulation of m 6 A methyltransferase METTL3 in β-cells controls the innate immune response in type 1 diabetes

Nature cell biology, 2024-03, Vol.26 (3), p.421

2024

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Lmx1a and Lmx1b regulate mitochondrial functions and survival of adult midbrain dopaminergic neurons

Proceedings of the National Academy of Sciences - PNAS, 2016-07, Vol.113 (30), p.E4387-E4396

2016

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Microscopy analysis neural network to solve detection, enumeration and segmentation from image-level annotations

Nature machine intelligence, 2022-05, Vol.4 (5), p.455-466

2022

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Landscape of stimulation-responsive chromatin across diverse human immune cells

Single-cell transcriptional profiling of human thymic stroma uncovers novel cellular heterogeneity in the thymic medulla

Thymic tuft cells promote an IL-4-enriched medulla and shape thymocyte development

Generation of Functional Thymic Epithelium from Human Embryonic Stem Cells that Supports Host T Cell Development

Stem cell-based multi-tissue platforms to model human autoimmune diabetes

From type 1 diabetes biology to therapy: The Human Islet Research Network

Mitigating Ischemic Injury of Stem Cell-Derived Insulin-Producing Cells after Transplant

Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitro

Selective deletion of human leukocyte antigens protects stem cell-derived islets from immune rejection

Nanoporous Immunoprotective Device for Stem-Cell-Derived β‑Cell Replacement Therapy

Development of a scalable method to isolate subsets of stem cell-derived pancreatic islet cells

Redox regulation of m6A methyltransferase METTL3 in β-cells controls the innate immune response in type 1 diabetes

Modeling human T1D-associated autoimmune processes

High-resolution epitope mapping of anti-Hu and anti-Yo autoimmunity by programmable phage display

Ikaros is a principal regulator of Aire + mTEC homeostasis, thymic mimetic cell diversity, and central tolerance

Low MOG Expression in Human Thymus, Implications for Central Tolerance Mechanisms in Autoimmunity Against MOG (P9-14.001)

Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency

Impaired thymic AIRE expression underlies autoantibodies against type I IFNs in humans with inborn errors of the alternative NF-κB pathway

Supporting Survival of Transplanted Stem‐Cell‐Derived Insulin‐Producing Cells in an Encapsulation Device Augmented with Controlled Release of Amino Acids

Modeling human T1D-associated autoimmune processesBox 1. Potential applications of models to understand the immune processes leading to human T1D.Box 2. Potential applications of models to evaluate treatments for human T1D

Thymic tuft cells promote an IL4-enriched medulla and shape thymocyte development

Redox regulation of m 6 A methyltransferase METTL3 in β-cells controls the innate immune response in type 1 diabetes

Lmx1a and Lmx1b regulate mitochondrial functions and survival of adult midbrain dopaminergic neurons

Microscopy analysis neural network to solve detection, enumeration and segmentation from image-level annotations

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