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On-chip spatiotemporal electrophysiological analysis of human stem cell derived cardiomyocytes enables quantitative assessment of proarrhythmia in drug development

Scientific reports, 2018-09, Vol.8 (1), p.14536-13, Article 14536

2018

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On-chip in vitro cell-network pre-clinical cardiac toxicity using spatiotemporal human cardiomyocyte measurement on a chip

Scientific reports, 2014-04, Vol.4 (1), p.4670, Article 4670

2014

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Involvement of Neurokinin Receptors in the Control of Pulsatile Luteinizing Hormone Secretion in Rats

Journal of Reproduction and Development, 2011, Vol.57(3), pp.409-415

2011

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Role of connexin 32 in acetaminophen toxicity in a knockout mice model

Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie, 2014-03, Vol.66 (2-3), p.103-110

2014

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Inflammatory Fibroid Polyp in the Duodenum of a Common Marmoset (Callithrix jacchus)

Toxicologic pathology, 2013-01, Vol.41 (1), p.80-85

2013

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Practical application of toxicogenomics for profiling toxicant-induced biological perturbations

International Journal of Molecular Sciences, 2010-09, Vol.11 (9), p.3397-3412

2010

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Ethylene Glycol Monomethyl Ether–Induced Toxicity Is Mediated through the Inhibition of Flavoprotein Dehydrogenase Enzyme Family

Toxicological sciences, 2010-12, Vol.118 (2), p.643-652

2010

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In vitro cytotoxicity assay to evaluate the toxicity of an electrophilic reactive metabolite using glutathione-depleted rat primary cultured hepatocytes

Chemico-biological interactions, 2010-12, Vol.188 (3), p.404-411

2010

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Toxicogenomic investigation on rat testicular toxicity elicited by 1,3-dinitrobenzene

Toxicology (Amsterdam), 2011-12, Vol.290 (2), p.169-177

2011

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Sex and circadian modulatory effects on rat liver as assessed by transcriptome analyses

The Journal of Toxicological Sciences, 2011/02/01, Vol.36(1), pp.9-22

2011

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Collaborative work on evaluation of ovarian toxicity by repeated-dose and fertility studies in female rats

The Journal of Toxicological Sciences, 2009/02/20, Vol.34(Special), pp.SP1-SP22

2009

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Effect of Hypertension on the Occurrence of Micro-hemorrhage in the Pancreatic Islet of Dahl Salt-sensitive Rats

Journal of Toxicologic Pathology, 2012, Vol.25(2), pp.155-161

2012

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A Spontaneous Ganglioneuroma in the Adrenal Medulla of a Young Wistar Hannover Rat

Toxicologic pathology, 2012-07, Vol.40 (5), p.807-809

2012

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Cerivastatin induces type-I fiber-, not type-II fiber-, predominant muscular toxicity in the young male F344 rats

The Journal of Toxicological Sciences, 2011/08/01, Vol.36(4), pp.445-452

2011

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Testicular toxicity induced by a triple neurokinin receptor antagonist in male dogs

Reproductive toxicology (Elmsford, N.Y.), 2011-05, Vol.31 (4), p.440-446

2011

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Mixed Type of Malignant Mesothelioma in an Aged Male ICR Mouse

Journal of Toxicologic Pathology, 2011, Vol.24(3), pp.169-172

2011

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Comprehensive analysis of hepatic gene and protein expression profiles on phenobarbital- or clofibrate-induced hepatic hypertrophy in dogs

The Journal of Toxicological Sciences, 2009/12/01, Vol.34(6), pp.647-661

2009

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Circadian modulation of hepatic transcriptome in transgenic rats expressing human growth hormone

The Journal of Toxicological Sciences, 2010/10/01, Vol.35(5), pp.673-685

2010

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Collaborative work on evaluation of ovarian toxicity 8) Two- or four-week repeated-dose studies and fertility study of Anastrozole in female rats

The Journal of Toxicological Sciences, 2009/02/20, Vol.34(Special), pp.SP91-SP99

2009

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Structural and numerical chromosome aberration inducers in liver micronucleus test in rats with partial hepatectomy

Mutation research, 2012-08, Vol.747 (1), p.98-103

2012

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Gene set-level network analysis using a toxicogenomics database

Genomics (San Diego, Calif.), 2010-07, Vol.96 (1), p.39-49

2010

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Chondrotoxicity and toxicokinetics of novel quinolone antibacterial agents DC-159a and DX-619 in juvenile rats

Toxicology (Amsterdam), 2010-10, Vol.276 (2), p.122-127

2010

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Which pathological condition is the most critical for drug-induced torsades de pointes?

Journal of pharmacological and toxicological methods, 2012-09, Vol.66 (2), p.194-194

2012

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Reproductive toxicity studies

Folia Pharmacologica Japonica, 2007, Vol.130(1), pp.62-66

Sanbuissho, Atsushi

2007

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Evaluation of fluctuation of temporal field potential duration and spatial conduction time in linear network of human-iPS cell derived cardiomyocytes for predictive cardiotoxicity measurement

Journal of pharmacological and toxicological methods, 2014-11, Vol.70 (3), p.315-315

2014

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On-chip spatiotemporal electrophysiological analysis of human stem cell derived cardiomyocytes enables quantitative assessment of proarrhythmia in drug development

On-chip in vitro cell-network pre-clinical cardiac toxicity using spatiotemporal human cardiomyocyte measurement on a chip

Involvement of Neurokinin Receptors in the Control of Pulsatile Luteinizing Hormone Secretion in Rats

Role of connexin 32 in acetaminophen toxicity in a knockout mice model

Inflammatory Fibroid Polyp in the Duodenum of a Common Marmoset (Callithrix jacchus)

Practical application of toxicogenomics for profiling toxicant-induced biological perturbations

Ethylene Glycol Monomethyl Ether–Induced Toxicity Is Mediated through the Inhibition of Flavoprotein Dehydrogenase Enzyme Family

In vitro cytotoxicity assay to evaluate the toxicity of an electrophilic reactive metabolite using glutathione-depleted rat primary cultured hepatocytes

Toxicogenomic investigation on rat testicular toxicity elicited by 1,3-dinitrobenzene

Sex and circadian modulatory effects on rat liver as assessed by transcriptome analyses

Collaborative work on evaluation of ovarian toxicity by repeated-dose and fertility studies in female rats

Effect of Hypertension on the Occurrence of Micro-hemorrhage in the Pancreatic Islet of Dahl Salt-sensitive Rats

A Spontaneous Ganglioneuroma in the Adrenal Medulla of a Young Wistar Hannover Rat

Cerivastatin induces type-I fiber-, not type-II fiber-, predominant muscular toxicity in the young male F344 rats

Testicular toxicity induced by a triple neurokinin receptor antagonist in male dogs

Mixed Type of Malignant Mesothelioma in an Aged Male ICR Mouse

Comprehensive analysis of hepatic gene and protein expression profiles on phenobarbital- or clofibrate-induced hepatic hypertrophy in dogs

Circadian modulation of hepatic transcriptome in transgenic rats expressing human growth hormone

Collaborative work on evaluation of ovarian toxicity 8) Two- or four-week repeated-dose studies and fertility study of Anastrozole in female rats

Structural and numerical chromosome aberration inducers in liver micronucleus test in rats with partial hepatectomy

Gene set-level network analysis using a toxicogenomics database

Chondrotoxicity and toxicokinetics of novel quinolone antibacterial agents DC-159a and DX-619 in juvenile rats

Which pathological condition is the most critical for drug-induced torsades de pointes?

Reproductive toxicity studies

Evaluation of fluctuation of temporal field potential duration and spatial conduction time in linear network of human-iPS cell derived cardiomyocytes for predictive cardiotoxicity measurement

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