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Drug screening to identify compounds to act as co-therapies for the treatment of Burkholderia species

PloS one, 2021-03, Vol.16 (3), p.e0248119-e0248119

2021

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Towards a Brucella vaccine for humans

FEMS microbiology reviews, 2010-05, Vol.34 (3), p.379-394

2010

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Design and characterization of novel hybrid antimicrobial peptides based on cecropin A, LL-37 and magainin II

Peptides (New York, N.Y. : 1980), 2012-02, Vol.33 (2), p.197-205

2012

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Intracellular replication of the well-armed pathogen Burkholderia pseudomallei

Current opinion in microbiology, 2016-02, Vol.29, p.94-103

2016

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Bacillus anthracis TIR Domain-Containing Protein Localises to Cellular Microtubule Structures and Induces Autophagy

PloS one, 2016-07, Vol.11 (7), p.e0158575-e0158575

2016

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A structural and biochemical comparison of Ribonuclease E homologues from pathogenic bacteria highlights species-specific properties

Scientific reports, 2019-05, Vol.9 (1), p.7952-7952, Article 7952

2019

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Global Analysis of Genes Essential for Francisella tularensis Schu S4 Growth In Vitro and for Fitness during Competitive Infection of Fischer 344 Rats

Journal of bacteriology, 2019-04, Vol.201 (7)

2019

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An Investigation into the Potential of Targeting Escherichia coli rne mRNA with Locked Nucleic Acid (LNA) Gapmers as an Antibacterial Strategy

Molecules (Basel, Switzerland), 2021-06, Vol.26 (11), p.3414

2021

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Demonstrating the Protective Efficacy of the Novel Fluoroquinolone Finafloxacin against an Inhalational Exposure to Burkholderia pseudomallei

Antimicrobial agents and chemotherapy, 2017-07, Vol.61 (7)

2017

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An integrated computational-experimental approach reveals Yersinia pestis genes essential across a narrow or a broad range of environmental conditions

BMC microbiology, 2017-07, Vol.17 (1), p.163-163, Article 163

2017

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High-throughput analysis of Yersinia pseudotuberculosis gene essentiality in optimised in vitro conditions, and implications for the speciation of Yersinia pestis

BMC microbiology, 2018-05, Vol.18 (1), p.46-46, Article 46

2018

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The Fluoroquinolone Finafloxacin Protects BALB/c Mice Against an Intranasal Infection With Francisella tularensis Strain SchuS4

Frontiers in microbiology, 2019-05, Vol.10, p.904-904

2019

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Characterization of New Virulence Factors Involved in the Intracellular Growth and Survival of Burkholderia pseudomallei

Infection and immunity, 2016-03, Vol.84 (3), p.701-710

2016

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Disulfiram, an alcohol dependence therapy, can inhibit the in vitro growth of Francisella tularensis

International journal of antimicrobial agents, 2019-07, Vol.54 (1), p.85-88

2019

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Burkholderia pseudomallei kynB plays a role in AQ production, biofilm formation, bacterial swarming and persistence

Research in microbiology, 2016-04, Vol.167 (3), p.159-167

2016

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Identification and analysis of novel small molecule inhibitors of RNase E: Implications for antibacterial targeting and regulation of RNase E

Biochemistry and biophysics reports, 2020-09, Vol.23, p.100773-100773, Article 100773

2020

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Inhaled Liposomal Ciprofloxacin Protects against a Lethal Infection in a Murine Model of Pneumonic Plague

Frontiers in microbiology, 2017-02, Vol.8, p.91-91

2017

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A Bioluminescent Francisella tularensis SCHU S4 Strain Enables Noninvasive Tracking of Bacterial Dissemination and the Evaluation of Antibiotics in an Inhalational Mouse Model of Tularemia

Antimicrobial agents and chemotherapy, 2016-12, Vol.60 (12), p.7206-7215

2016

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Galleria mellonella as a model system to test the pharmacokinetics and efficacy of antibiotics against Burkholderia pseudomallei

International journal of antimicrobial agents, 2013-04, Vol.41 (4), p.330-336

2013

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Bacterial TIR-containing proteins and host innate immune system evasion

Medical microbiology and immunology, 2013-02, Vol.202 (1), p.1-10

2013

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The potential of liposome-encapsulated ciprofloxacin as a tularemia therapy

Frontiers in cellular and infection microbiology, 2014, Vol.4, p.79-79

2014

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Liposome Encapsulation of Ciprofloxacin Improves Protection against Highly Virulent Francisella tularensis Strain Schu S4

Antimicrobial agents and chemotherapy, 2014-06, Vol.58 (6), p.3053-3059

2014

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Identification of a LolC Homologue in Burkholderia pseudomallei, a Novel Protective Antigen for Melioidosis

Infection and Immunity, 2007-08, Vol.75 (8), p.4173-4180

2007

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Phenotypic and functional characterization of human memory T cell responses to Burkholderia pseudomallei

PLoS neglected tropical diseases, 2009-04, Vol.3 (4), p.e407-e407

2009

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Microbial TIR domains: not necessarily agents of subversion?

Trends in microbiology (Regular ed.), 2009-09, Vol.17 (9), p.393-398

2009

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Drug screening to identify compounds to act as co-therapies for the treatment of Burkholderia species

Towards a Brucella vaccine for humans

Design and characterization of novel hybrid antimicrobial peptides based on cecropin A, LL-37 and magainin II

Intracellular replication of the well-armed pathogen Burkholderia pseudomallei

Bacillus anthracis TIR Domain-Containing Protein Localises to Cellular Microtubule Structures and Induces Autophagy

A structural and biochemical comparison of Ribonuclease E homologues from pathogenic bacteria highlights species-specific properties

Global Analysis of Genes Essential for Francisella tularensis Schu S4 Growth In Vitro and for Fitness during Competitive Infection of Fischer 344 Rats

An Investigation into the Potential of Targeting Escherichia coli rne mRNA with Locked Nucleic Acid (LNA) Gapmers as an Antibacterial Strategy

Demonstrating the Protective Efficacy of the Novel Fluoroquinolone Finafloxacin against an Inhalational Exposure to Burkholderia pseudomallei

An integrated computational-experimental approach reveals Yersinia pestis genes essential across a narrow or a broad range of environmental conditions

High-throughput analysis of Yersinia pseudotuberculosis gene essentiality in optimised in vitro conditions, and implications for the speciation of Yersinia pestis

The Fluoroquinolone Finafloxacin Protects BALB/c Mice Against an Intranasal Infection With Francisella tularensis Strain SchuS4

Characterization of New Virulence Factors Involved in the Intracellular Growth and Survival of Burkholderia pseudomallei

Disulfiram, an alcohol dependence therapy, can inhibit the in vitro growth of Francisella tularensis

Burkholderia pseudomallei kynB plays a role in AQ production, biofilm formation, bacterial swarming and persistence

Identification and analysis of novel small molecule inhibitors of RNase E: Implications for antibacterial targeting and regulation of RNase E

Inhaled Liposomal Ciprofloxacin Protects against a Lethal Infection in a Murine Model of Pneumonic Plague

A Bioluminescent Francisella tularensis SCHU S4 Strain Enables Noninvasive Tracking of Bacterial Dissemination and the Evaluation of Antibiotics in an Inhalational Mouse Model of Tularemia

Galleria mellonella as a model system to test the pharmacokinetics and efficacy of antibiotics against Burkholderia pseudomallei

Bacterial TIR-containing proteins and host innate immune system evasion

The potential of liposome-encapsulated ciprofloxacin as a tularemia therapy

Liposome Encapsulation of Ciprofloxacin Improves Protection against Highly Virulent Francisella tularensis Strain Schu S4

Identification of a LolC Homologue in Burkholderia pseudomallei, a Novel Protective Antigen for Melioidosis

Phenotypic and functional characterization of human memory T cell responses to Burkholderia pseudomallei

Microbial TIR domains: not necessarily agents of subversion?

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