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HIF Transcription Factors, Inflammation, and Immunity

Immunity (Cambridge, Mass.), 2014-10, Vol.41 (4), p.518-528

2014

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CAR-T Cells Hit the Tumor Microenvironment: Strategies to Overcome Tumor Escape

Frontiers in immunology, 2020-06, Vol.11, p.1109-1109

2020

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Structural insights into Siglec-15 reveal glycosylation dependency for its interaction with T cells through integrin CD11b

Nature communications, 2023-06, Vol.14 (1), p.3496-3496, Article 3496

2023

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The two enantiomers of 2-hydroxyglutarate differentially regulate cytotoxic T cell function

Cell reports (Cambridge), 2023-09, Vol.42 (9), p.113013-113013, Article 113013

2023

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Hypoxia Promotes Syndecan-3 Expression in the Tumor Microenvironment

Frontiers in immunology, 2020-09, Vol.11, p.586977-586977

2020

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SimB16: modeling induced immune system response against B16-melanoma

PloS one, 2011-10, Vol.6 (10), p.e26523-e26523

2011

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Assessing the Mobility of Severe Acute Respiratory Syndrome Coronavirus-2 Spike Protein Glycans by Structural and Computational Methods

Frontiers in microbiology, 2022-04, Vol.13, p.870938

2022

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A cell-engineered system to assess tumor cell sensitivity to CD8+ T cell-mediated cytotoxicity

Oncoimmunology, 2019-08, Vol.8 (8), p.1-10

2019

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Hypoxia reduces cell attachment of SARS-CoV-2 spike protein by modulating the expression of ACE2, neuropilin-1, syndecan-1 and cellular heparan sulfate

Emerging microbes & infections, 2021-01, Vol.10 (1), p.1065-1076

2021

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Lysine 63 Polyubiquitination in Immunotherapy and in Cancer-promoting Inflammation

Clinical cancer research, 2009-11, Vol.15 (22), p.6751-6757

2009

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Immune Response Regulation in the Tumor Microenvironment by Hypoxia

Seminars in oncology, 2015-06, Vol.42 (3), p.378-386

2015

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The spike of SARS-CoV-2 promotes metabolic rewiring in hepatocytes

Communications biology, 2022-08, Vol.5 (1), p.827-827, Article 827

2022

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Factor-inhibiting HIF (FIH) promotes lung cancer progression

JCI insight, 2023-10, Vol.8 (20)

2023

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Modelling pulmonary microthrombosis coupled to metastasis: distinct effects of thrombogenesis on tumorigenesis

Biology open, 2017-05, Vol.6 (5), p.688-697

2017

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Molecular Pathways: Hypoxia Response in Immune Cells Fighting or Promoting Cancer

Clinical cancer research, 2012-03, Vol.18 (5), p.1207-1213

2012

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Dendritic cells take up and present antigens from viable and apoptotic polymorphonuclear leukocytes

PloS one, 2011-12, Vol.6 (12), p.e29300-e29300

2011

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Liver gene transfer of interkeukin-15 constructs that become part of circulating high density lipoproteins for immunotherapy

PloS one, 2012-12, Vol.7 (12), p.e52370

2012

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An HIF-1α/VEGF-A Axis in Cytotoxic T Cells Regulates Tumor Progression

Cancer cell, 2017-11, Vol.32 (5), p.669-683.e5

2017

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S-2-hydroxyglutarate regulates CD8 + T-lymphocyte fate

Nature (London), 2016-12, Vol.540 (7632), p.236-241

2016

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Constitutive Glycolytic Metabolism Supports CD8+ T Cell Effector Memory Differentiation during Viral Infection

Immunity (Cambridge, Mass.), 2016-11, Vol.45 (5), p.1024-1037

2016

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The Factor Inhibiting HIF Asparaginyl Hydroxylase Regulates Oxidative Metabolism and Accelerates Metabolic Adaptation to Hypoxia

Cell metabolism, 2018-04, Vol.27 (4), p.898-913.e7

2018

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Hypoxia-induced soluble CD137 in malignant cells blocks CD137L-costimulation as an immune escape mechanism

Oncoimmunology, 2016-01, Vol.5 (1), p.e1062967-e1062967

2016

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Palettes of Vaccines and Immunostimulatory Monoclonal Antibodies for Combination

Clinical cancer research, 2009-03, Vol.15 (5), p.1507-1509

2009

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Treatment with anti-CD137 mAbs causes intense accumulations of liver T cells without selective antitumor immunotherapeutic effects in this organ

Cancer Immunology, Immunotherapy, 2010-08, Vol.59 (8), p.1223-1233

2010

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HIF Transcription Factors, Inflammation, and Immunity

CAR-T Cells Hit the Tumor Microenvironment: Strategies to Overcome Tumor Escape

Structural insights into Siglec-15 reveal glycosylation dependency for its interaction with T cells through integrin CD11b

The two enantiomers of 2-hydroxyglutarate differentially regulate cytotoxic T cell function

Hypoxia Promotes Syndecan-3 Expression in the Tumor Microenvironment

SimB16: modeling induced immune system response against B16-melanoma

Assessing the Mobility of Severe Acute Respiratory Syndrome Coronavirus-2 Spike Protein Glycans by Structural and Computational Methods

A cell-engineered system to assess tumor cell sensitivity to CD8+ T cell-mediated cytotoxicity

Hypoxia reduces cell attachment of SARS-CoV-2 spike protein by modulating the expression of ACE2, neuropilin-1, syndecan-1 and cellular heparan sulfate

Lysine 63 Polyubiquitination in Immunotherapy and in Cancer-promoting Inflammation

Immune Response Regulation in the Tumor Microenvironment by Hypoxia

The spike of SARS-CoV-2 promotes metabolic rewiring in hepatocytes

Factor-inhibiting HIF (FIH) promotes lung cancer progression

Modelling pulmonary microthrombosis coupled to metastasis: distinct effects of thrombogenesis on tumorigenesis

Molecular Pathways: Hypoxia Response in Immune Cells Fighting or Promoting Cancer

Dendritic cells take up and present antigens from viable and apoptotic polymorphonuclear leukocytes

Liver gene transfer of interkeukin-15 constructs that become part of circulating high density lipoproteins for immunotherapy

An HIF-1α/VEGF-A Axis in Cytotoxic T Cells Regulates Tumor Progression

S-2-hydroxyglutarate regulates CD8 + T-lymphocyte fate

Constitutive Glycolytic Metabolism Supports CD8+ T Cell Effector Memory Differentiation during Viral Infection

Design and Efficacy of a Monovalent Bispecific PD-1/CTLA4 Antibody That Enhances CTLA4 Blockade on PD-1 + Activated T Cells

The Factor Inhibiting HIF Asparaginyl Hydroxylase Regulates Oxidative Metabolism and Accelerates Metabolic Adaptation to Hypoxia

Hypoxia-induced soluble CD137 in malignant cells blocks CD137L-costimulation as an immune escape mechanism

Palettes of Vaccines and Immunostimulatory Monoclonal Antibodies for Combination

Treatment with anti-CD137 mAbs causes intense accumulations of liver T cells without selective antitumor immunotherapeutic effects in this organ

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