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Cerebral cavernous malformations arise from endothelial gain of MEKK3-KLF2/4 signalling

Nature (London), 2016-04, Vol.532 (7597), p.122-126

2016

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Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains

Proceedings of the National Academy of Sciences - PNAS, 2013-09, Vol.110 (38), p.15247-15252

2013

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The selectivity of protein kinase inhibitors: a further update

Biochemical journal, 2007-12, Vol.408 (3), p.297-315

2007

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Mitogen-activated protein kinases in innate immunity

Nature reviews. Immunology, 2013-09, Vol.13 (9), p.679

2013

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The Cerebral Cavernous Malformation Pathway Controls Cardiac Development via Regulation of Endocardial MEKK3 Signaling and KLF Expression

Developmental cell, 2015-01, Vol.32 (2), p.168-180

2015

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RAS―MAPK―MSK1 pathway modulates ataxin 1 protein levels and toxicity in SCA1

Nature (London), 2013-06, Vol.498 (7454), p.325-331

2013

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STAT3 activation by E6 is essential for the differentiation-dependent HPV18 life cycle

PLoS pathogens, 2018-04, Vol.14 (4), p.e1006975

2018

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Experience recruits MSK1 to expand the dynamic range of synapses and enhance cognition

The Journal of neuroscience, 2020-06, Vol.40 (24), p.4644-4660

2020

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Quantitative proteomics reveals tissue-specific, infection-induced and species-specific neutrophil protein signatures

Scientific reports, 2024-03, Vol.14 (1), p.5966-5966, Article 5966

2024

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Phosphorylation of CRTC3 by the salt-inducible kinases controls the interconversion of classically activated and regulatory macrophages

Proceedings of the National Academy of Sciences - PNAS, 2012-10, Vol.109 (42), p.16986-16991

2012

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Polyubiquitin binding to ABIN1 is required to prevent autoimmunity

The Journal of experimental medicine, 2011-06, Vol.208 (6), p.1215-1228

2011

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miR-132/212 knockout mice reveal roles for these miRNAs in regulating cortical synaptic transmission and plasticity

PloS one, 2013-04, Vol.8 (4), p.e62509-e62509

2013

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Regulation of the miR-212/132 locus by MSK1 and CREB in response to neurotrophins

Biochemical journal, 2010-06, Vol.428 (2), p.281-291

2010

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Dectin-1 regulates IL-10 production via a MSK1/2 and CREB dependent pathway and promotes the induction of regulatory macrophage markers

PloS one, 2013-03, Vol.8 (3), p.e60086-e60086

2013

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The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling

Nature immunology, 2008-09, Vol.9 (9), p.1028-1036

2008

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The catalytic subunit of the system L1 amino acid transporter (slc7a5) facilitates nutrient signalling in mouse skeletal muscle

PloS one, 2014-02, Vol.9 (2), p.e89547-e89547

2014

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Subverting Toll-Like Receptor Signaling by Bacterial Pathogens

Frontiers in immunology, 2015-12, Vol.6, p.607-607

2015

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p38γ and p38δ kinases regulate the Toll-like receptor 4 (TLR4)-induced cytokine production by controlling ERK1/2 protein kinase pathway activation

Proceedings of the National Academy of Sciences - PNAS, 2012-07, Vol.109 (28), p.11200-11205

2012

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Generation of a chemical genetic model for JAK3

Scientific reports, 2021-05, Vol.11 (1), p.10093-10093, Article 10093

2021

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The MAPK-activated kinase Rsk controls an acute Toll-like receptor signaling response in dendritic cells and is activated through two distinct pathways

Nature Immunology, 2007-11, Vol.8 (11), p.1227-1235

2007

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Micro-CT Imaging Reveals Mekk3 Heterozygosity Prevents Cerebral Cavernous Malformations in Ccm2-Deficient Mice

PloS one, 2016-08, Vol.11 (8), p.e0160833

2016

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The Chromatin Modifier MSK1/2 Suppresses Endocrine Cell Fates during Mouse Pancreatic Development

PloS one, 2016-12, Vol.11 (12), p.e0166703-e0166703

2016

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MSK1 regulates the transcription of IL-1ra in response to TLR activation in macrophages

Biochemical journal, 2010-01, Vol.425 (3), p.595-602

2010

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Inhibition of SIK2 and SIK3 during differentiation enhances the anti-inflammatory phenotype of macrophages

Biochemical journal, 2017-02, Vol.474 (4), p.521-537

2017

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Inhibition of JAKs in macrophages increases lipopolysaccharide-induced cytokine production by blocking IL-10-mediated feedback

The Journal of immunology (1950), 2012-09, Vol.189 (6), p.2784-2792

2012

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Cerebral cavernous malformations arise from endothelial gain of MEKK3-KLF2/4 signalling

Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains

The selectivity of protein kinase inhibitors: a further update

Mitogen-activated protein kinases in innate immunity

The Cerebral Cavernous Malformation Pathway Controls Cardiac Development via Regulation of Endocardial MEKK3 Signaling and KLF Expression

RAS―MAPK―MSK1 pathway modulates ataxin 1 protein levels and toxicity in SCA1

STAT3 activation by E6 is essential for the differentiation-dependent HPV18 life cycle

Experience recruits MSK1 to expand the dynamic range of synapses and enhance cognition

Quantitative proteomics reveals tissue-specific, infection-induced and species-specific neutrophil protein signatures

Phosphorylation of CRTC3 by the salt-inducible kinases controls the interconversion of classically activated and regulatory macrophages

Polyubiquitin binding to ABIN1 is required to prevent autoimmunity

miR-132/212 knockout mice reveal roles for these miRNAs in regulating cortical synaptic transmission and plasticity

Regulation of the miR-212/132 locus by MSK1 and CREB in response to neurotrophins

Dectin-1 regulates IL-10 production via a MSK1/2 and CREB dependent pathway and promotes the induction of regulatory macrophage markers

The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling

The catalytic subunit of the system L1 amino acid transporter (slc7a5) facilitates nutrient signalling in mouse skeletal muscle

Subverting Toll-Like Receptor Signaling by Bacterial Pathogens

p38γ and p38δ kinases regulate the Toll-like receptor 4 (TLR4)-induced cytokine production by controlling ERK1/2 protein kinase pathway activation

Generation of a chemical genetic model for JAK3

The MAPK-activated kinase Rsk controls an acute Toll-like receptor signaling response in dendritic cells and is activated through two distinct pathways

Micro-CT Imaging Reveals Mekk3 Heterozygosity Prevents Cerebral Cavernous Malformations in Ccm2-Deficient Mice

The Chromatin Modifier MSK1/2 Suppresses Endocrine Cell Fates during Mouse Pancreatic Development

MSK1 regulates the transcription of IL-1ra in response to TLR activation in macrophages

Inhibition of SIK2 and SIK3 during differentiation enhances the anti-inflammatory phenotype of macrophages

Inhibition of JAKs in macrophages increases lipopolysaccharide-induced cytokine production by blocking IL-10-mediated feedback

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