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A Compendium of Mutational Signatures of Environmental Agents

Cell, 2019-05, Vol.177 (4), p.821-836.e16

2019

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DNA Adducts Formed by Aristolochic Acid Are Unique Biomarkers of Exposure and Explain the Initiation Phase of Upper Urothelial Cancer

International journal of molecular sciences, 2017-10, Vol.18 (10), p.2144

2017

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MosSCI‐mediated exogenous gene expression is modulated by genomic positioning

Biotechnology journal, 2023-09, Vol.18 (9), p.e2300062-n/a

2023

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Assessing the impact of Benzo[a]pyrene on Marine Mussels: Application of a novel targeted low density microarray complementing classical biomarker responses

PloS one, 2017-06, Vol.12 (6), p.e0178460

2017

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Metabolic Activation of Benzo[ a ]pyrene by Human Tissue Organoid Cultures

International journal of molecular sciences, 2022-12, Vol.24 (1), p.606

2022

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Co-Exposure to Aristolochic Acids I and II Increases DNA Adduct Formation Responsible for Aristolochic Acid I-Mediated Carcinogenicity in Rats

International journal of molecular sciences, 2021-10, Vol.22 (19), p.10479

2021

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Tissue-specific in vivo genetic toxicity of nine polycyclic aromatic hydrocarbons assessed using the Muta™Mouse transgenic rodent assay

Toxicology and applied pharmacology, 2016-01, Vol.290, p.31-42

2016

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Polycyclic aromatic hydrocarbons as skin carcinogens: Comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse

Toxicology and applied pharmacology, 2012-11, Vol.264 (3), p.377-386

2012

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The impact of individual cytochrome P450 enzymes on oxidative metabolism of benzo[a]pyrene in human livers

Environmental and molecular mutagenesis, 2016-04, Vol.57 (3), p.229-235

2016

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Influence of cell cycle on responses of MCF-7 cells to benzo[a]pyrene

BMC genomics, 2011-06, Vol.12 (1), p.333-333, Article 333

2011

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Enzymes metabolizing aristolochic acid and their contribution to the development of aristolochic acid nephropathy and urothelial cancer

Current drug metabolism, 2013-07, Vol.14 (6), p.695

2013

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The Histone Deacetylase Inhibitor Valproic Acid Exerts a Synergistic Cytotoxicity with the DNA-Damaging Drug Ellipticine in Neuroblastoma Cells

International journal of molecular sciences, 2018-01, Vol.19 (1), p.164

2018

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3-Nitrobenzanthrone, a potential human cancer hazard in diesel exhaust and urban air pollution: a review of the evidence

Mutagenesis, 2005-11, Vol.20 (6), p.399-410

Arlt, Volker M

2005

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Lagos lagoon sediment organic extracts and polycyclic aromatic hydrocarbons induce embryotoxic, teratogenic and genotoxic effects in Danio rerio (zebrafish) embryos

Environmental science and pollution research international, 2016-07, Vol.23 (14), p.14489-14501

2016

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C. elegans aging is modulated by hydrogen sulfide and the sulfhydrylase/cysteine synthase cysl-2

PloS one, 2013-11, Vol.8 (11), p.e80135

2013

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A Mechanism of O-Demethylation of Aristolochic Acid I by Cytochromes P450 and Their Contributions to This Reaction in Human and Rat Livers: Experimental and Theoretical Approaches

International journal of molecular sciences, 2015-11, Vol.16 (11), p.27561-27575

2015

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Bulky DNA adducts, microRNA profiles, and lipid biomarkers in Norwegian tunnel finishing workers occupationally exposed to diesel exhaust

Occupational and environmental medicine (London, England), 2019-01, Vol.76 (1), p.10

2019

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Mechanisms of enzyme-catalyzed reduction of two carcinogenic nitro-aromatics, 3-nitrobenzanthrone and aristolochic acid I: Experimental and theoretical approaches

International journal of molecular sciences, 2014-06, Vol.15 (6), p.10271-10295

2014

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Metabolic activation of carcinogenic aristolochic acid, a risk factor for Balkan endemic nephropathy

Mutation research, 2008-01, Vol.658 (1-2), p.55-67

2008

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Time- and concentration-dependent changes in gene expression induced by benzo(a)pyrene in two human cell lines, MCF-7 and HepG2

BMC genomics, 2006-10, Vol.7 (1), p.260-260, Article 260

2006

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The anticancer drug ellipticine activated with cytochrome P450 mediates DNA damage determining its pharmacological efficiencies: studies with rats, Hepatic Cytochrome P450 Reductase Null (HRN™) mice and pure enzymes

International journal of molecular sciences, 2014-12, Vol.16 (1), p.284-306

2014

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Induction of cytochromes P450 1A1 and 1A2 suppresses formation of DNA adducts by carcinogenic aristolochic acid I in rats in vivo

Toxicology (Amsterdam), 2016-02, Vol.344, p.7-18

2016

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Cytochrome b5 and epoxide hydrolase contribute to benzo[a]pyrene-DNA adduct formation catalyzed by cytochrome P450 1A1 under low NADPH:P450 oxidoreductase conditions

Toxicology (Amsterdam), 2014-04, Vol.318, p.1-12

2014

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Bioactivation versus Detoxication of the Urothelial Carcinogen Aristolochic Acid I by Human Cytochrome P450 1A1 and 1A2

Toxicological sciences, 2012-02, Vol.125 (2), p.345-358

2012

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A Compendium of Mutational Signatures of Environmental Agents

DNA Adducts Formed by Aristolochic Acid Are Unique Biomarkers of Exposure and Explain the Initiation Phase of Upper Urothelial Cancer

MosSCI‐mediated exogenous gene expression is modulated by genomic positioning

Assessing the impact of Benzo[a]pyrene on Marine Mussels: Application of a novel targeted low density microarray complementing classical biomarker responses

Metabolic Activation of Benzo[ a ]pyrene by Human Tissue Organoid Cultures

Co-Exposure to Aristolochic Acids I and II Increases DNA Adduct Formation Responsible for Aristolochic Acid I-Mediated Carcinogenicity in Rats

Tissue-specific in vivo genetic toxicity of nine polycyclic aromatic hydrocarbons assessed using the Muta™Mouse transgenic rodent assay

Polycyclic aromatic hydrocarbons as skin carcinogens: Comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse

The impact of individual cytochrome P450 enzymes on oxidative metabolism of benzo[a]pyrene in human livers

Influence of cell cycle on responses of MCF-7 cells to benzo[a]pyrene

Enzymes metabolizing aristolochic acid and their contribution to the development of aristolochic acid nephropathy and urothelial cancer

The Histone Deacetylase Inhibitor Valproic Acid Exerts a Synergistic Cytotoxicity with the DNA-Damaging Drug Ellipticine in Neuroblastoma Cells

3-Nitrobenzanthrone, a potential human cancer hazard in diesel exhaust and urban air pollution: a review of the evidence

Lagos lagoon sediment organic extracts and polycyclic aromatic hydrocarbons induce embryotoxic, teratogenic and genotoxic effects in Danio rerio (zebrafish) embryos

C. elegans aging is modulated by hydrogen sulfide and the sulfhydrylase/cysteine synthase cysl-2

A Mechanism of O-Demethylation of Aristolochic Acid I by Cytochromes P450 and Their Contributions to This Reaction in Human and Rat Livers: Experimental and Theoretical Approaches

Bulky DNA adducts, microRNA profiles, and lipid biomarkers in Norwegian tunnel finishing workers occupationally exposed to diesel exhaust

Mechanisms of enzyme-catalyzed reduction of two carcinogenic nitro-aromatics, 3-nitrobenzanthrone and aristolochic acid I: Experimental and theoretical approaches

Metabolic activation of carcinogenic aristolochic acid, a risk factor for Balkan endemic nephropathy

Time- and concentration-dependent changes in gene expression induced by benzo(a)pyrene in two human cell lines, MCF-7 and HepG2

The anticancer drug ellipticine activated with cytochrome P450 mediates DNA damage determining its pharmacological efficiencies: studies with rats, Hepatic Cytochrome P450 Reductase Null (HRN™) mice and pure enzymes

Induction of cytochromes P450 1A1 and 1A2 suppresses formation of DNA adducts by carcinogenic aristolochic acid I in rats in vivo

Cytochrome b5 and epoxide hydrolase contribute to benzo[a]pyrene-DNA adduct formation catalyzed by cytochrome P450 1A1 under low NADPH:P450 oxidoreductase conditions

Blocking TGF-β Signaling Pathway Preserves Mitochondrial Proteostasis and Reduces Early Activation of PDGFRβ+ Pericytes in Aristolochic Acid Induced Acute Kidney Injury in Wistar Male Rats

Bioactivation versus Detoxication of the Urothelial Carcinogen Aristolochic Acid I by Human Cytochrome P450 1A1 and 1A2

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