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Enantiomeric Amino Acid Schiff Base Copper(II) Complexes as a New Class of RNA-Targeted Metallo-Intercalators: Single X‑ray Crystal Structural Details, Comparative in Vitro DNA/RNA Binding Profile, Cleavage, and Cytotoxicity

ACS omega, 2019-04, Vol.4 (4), p.7691-7705

2019

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Ru(II)( ƞ 6 - p -cymene) Conjugates Loaded onto Graphene Oxide: An Effective pH-Responsive Anticancer Drug Delivery System

Molecules (Basel, Switzerland), 2022-11, Vol.27 (21), p.7592

2022

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Synthesis and characterization of new transition metal {Cu(II), Ni(II) and Co(II)} L-phenylalanine-DACH conjugate complexes: in vitro DNA binding, cleavage and molecular docking studies

Journal of photochemistry and photobiology. B, Biology, 2014-07, Vol.136, p.1-11

2014

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Biological evaluation of dinuclear copper complex/dichloroacetic acid cocrystal against human breast cancer: design, synthesis, characterization, DFT studies and cytotoxicity assays

RSC advances, 2017, Vol.7 (76), p.47920-47932

2017

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Synthesis, characterization and in vitro DNA binding and cleavage studies of Cu(II)/Zn(II) dipeptide complexes

Journal of photochemistry and photobiology. B, Biology, 2013-04, Vol.121, p.75-85

2013

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Chiral transition metal complexes: Synthetic approach and biological applications

Inorganica Chimica Acta, 2017-03, Vol.458, p.8-27

2017

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New modulated design, docking and synthesis of carbohydrate-conjugate heterobimetallic CuII–SnIV complex as potential topoisomerase II inhibitor: In vitro DNA binding, cleavage and cytotoxicity against human cancer cell lines

European journal of medicinal chemistry, 2014-03, Vol.74, p.694-702

2014

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Enantiomeric recognition of chiral L– and D–penicillamine Zinc(ii) complexes: DNA binding behavior and cleavage studies

RSC advances, 2012-01, Vol.2 (15), p.6354

2012

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Repurposing the antihistamine drug bilastine as an anti-cancer metallic drug entity: synthesis and single-crystal X-ray structure analysis of metal-based bilastine and phen Co(II), Cu(II) and Zn(II) tailored anticancer chemotherapeutic agents against resistant cancer cells

Dalton transactions : an international journal of inorganic chemistry, 2024-06, Vol.53 (24), p.10126

2024

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Biochemical pathways of copper complexes: progress over the past 5 years

Drug discovery today, 2021-04, Vol.26 (4), p.1086-1096

2021

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Synthesis and characterization of dinuclear macrocyclic cobalt(II), copper(II) and zinc(II) complexes derived from 2,2,2 ′,2 ′- S, S[bis(bis- N, N-2-thiobenzimidazolyloxalato-1,2-ethane)]: DNA binding and cleavage studies

European journal of medicinal chemistry, 2009-02, Vol.44 (2), p.834-844

2009

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Repurposing the antihistamine drug bilastine as an anti-cancer metallic drug entity: synthesis and single-crystal X-ray structure analysis of metal-based bilastine and phen [Co(), Cu() and Zn()] tailored anticancer chemotherapeutic agents against resistant cancer cells

Dalton transactions : an international journal of inorganic chemistry, 2024-06, Vol.53 (24), p.1126-1141

2024

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New Tailored RNA-Targeted Organometallic Drug Candidates against Huh7 (Liver) and Du145 (Prostate) Cancer Cell Lines

ACS omega, 2020-06, Vol.5 (25), p.15218-15228

2020

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Advancement of metal compounds as therapeutic and diagnostic metallodrugs: Current frontiers and future perspectives

Coordination chemistry reviews, 2021-10, Vol.445, p.214104, Article 214104

2021

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Synthesis and characterization of copper(II) norcraugsodine complexes: Their in vitro binding studies with therapeutic targets (ct-DNA/tRNA/BSA), cleavage, and cytotoxicity profile

Journal of molecular structure, 2024-05, Vol.1304, p.137692, Article 137692

2024

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Quercetin-phenylalanine 3d-transition metal-based {Co(II), Ni(II) & Cu(II)} intercalative therapeutic agents: DNA & BSA interaction studies in vitro and cleavage activity

International journal of biological macromolecules, 2024-01, Vol.254 (Pt 1), p.127521-127521, Article 127521

2024

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Development and future prospects of selective organometallic compounds as anticancer drug candidates exhibiting novel modes of action

European journal of medicinal chemistry, 2019-08, Vol.175, p.269-286

2019

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Synthesis, characterization and in vitro DNA binding of chromone Schiff base organotin(IV) complexes

Journal of organometallic chemistry, 2013-10, Vol.743, p.55-62

2013

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New modulated design and synthesis of quercetin–CuII/ZnII–Sn2IV scaffold as anticancer agents: in vitro DNA binding profile, DNA cleavage pathway and Topo-I activity

Dalton transactions : an international journal of inorganic chemistry, 2013, Vol.42 (27), p.10029

2013

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Clinical developments of antitumor polymer therapeutics

RSC advances, 2019-08, Vol.9 (43), p.24699-24721

2019

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In vitro DNA binding profile of enantiomeric dinuclear Cu(II)/Ni(II) complexes derived from l–/d–histidine–terepthaldehyde reduced Schiff base as potential chemotherapeutic agents

Journal of photochemistry and photobiology. B, Biology, 2016-11, Vol.164, p.83-95

2016

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Current and future potential of metallo drugs: Revisiting DNA-binding of metal containing molecules and their diverse mechanism of action

Inorganica Chimica Acta, 2016-04, Vol.444, p.1-22

2016

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Design, synthesis and characterization of novel chromone based-copper(ii) antitumor agents with N , N -donor ligands: comparative DNA/RNA binding profile and cytotoxicity

RSC advances, 2018-11, Vol.8 (65), p.37375-37390

2018

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Comprehensive biological {DNA/RNA binding profile, cleavage &cytotoxicity activity} of structurally well-characterized chromone-appended Cu(II)(L1-3)(phen) potential anticancer drug candidates

Polyhedron, 2022-03, Vol.214, p.115638, Article 115638

2022

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DNA Binding Studies of Novel Copper(II) Complexes Containing l -Tryptophan as Chiral Auxiliary: In Vitro Antitumor Activity of Cu−Sn 2 Complex in Human Neuroblastoma Cells

Inorganic chemistry, 2007-04, Vol.46 (8), p.3072-3082

2007

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Enantiomeric Amino Acid Schiff Base Copper(II) Complexes as a New Class of RNA-Targeted Metallo-Intercalators: Single X‑ray Crystal Structural Details, Comparative in Vitro DNA/RNA Binding Profile, Cleavage, and Cytotoxicity

Ru(II)( ƞ 6 - p -cymene) Conjugates Loaded onto Graphene Oxide: An Effective pH-Responsive Anticancer Drug Delivery System

Synthesis and characterization of new transition metal {Cu(II), Ni(II) and Co(II)} L-phenylalanine-DACH conjugate complexes: in vitro DNA binding, cleavage and molecular docking studies

Biological evaluation of dinuclear copper complex/dichloroacetic acid cocrystal against human breast cancer: design, synthesis, characterization, DFT studies and cytotoxicity assays

Synthesis, characterization and in vitro DNA binding and cleavage studies of Cu(II)/Zn(II) dipeptide complexes

Chiral transition metal complexes: Synthetic approach and biological applications

New modulated design, docking and synthesis of carbohydrate-conjugate heterobimetallic CuII–SnIV complex as potential topoisomerase II inhibitor: In vitro DNA binding, cleavage and cytotoxicity against human cancer cell lines

Enantiomeric recognition of chiral L– and D–penicillamine Zinc(ii) complexes: DNA binding behavior and cleavage studies

Repurposing the antihistamine drug bilastine as an anti-cancer metallic drug entity: synthesis and single-crystal X-ray structure analysis of metal-based bilastine and phen Co(II), Cu(II) and Zn(II) tailored anticancer chemotherapeutic agents against resistant cancer cells

Biochemical pathways of copper complexes: progress over the past 5 years

Synthesis and characterization of dinuclear macrocyclic cobalt(II), copper(II) and zinc(II) complexes derived from 2,2,2 ′,2 ′- S, S[bis(bis- N, N-2-thiobenzimidazolyloxalato-1,2-ethane)]: DNA binding and cleavage studies

Repurposing the antihistamine drug bilastine as an anti-cancer metallic drug entity: synthesis and single-crystal X-ray structure analysis of metal-based bilastine and phen [Co(), Cu() and Zn()] tailored anticancer chemotherapeutic agents against resistant cancer cells

New Tailored RNA-Targeted Organometallic Drug Candidates against Huh7 (Liver) and Du145 (Prostate) Cancer Cell Lines

Advancement of metal compounds as therapeutic and diagnostic metallodrugs: Current frontiers and future perspectives

Synthesis and characterization of copper(II) norcraugsodine complexes: Their in vitro binding studies with therapeutic targets (ct-DNA/tRNA/BSA), cleavage, and cytotoxicity profile

Quercetin-phenylalanine 3d-transition metal-based {Co(II), Ni(II) & Cu(II)} intercalative therapeutic agents: DNA & BSA interaction studies in vitro and cleavage activity

Development and future prospects of selective organometallic compounds as anticancer drug candidates exhibiting novel modes of action

Synthesis, characterization and in vitro DNA binding of chromone Schiff base organotin(IV) complexes

New modulated design and synthesis of quercetin–CuII/ZnII–Sn2IV scaffold as anticancer agents: in vitro DNA binding profile, DNA cleavage pathway and Topo-I activity

Clinical developments of antitumor polymer therapeutics

In vitro DNA binding profile of enantiomeric dinuclear Cu(II)/Ni(II) complexes derived from l–/d–histidine–terepthaldehyde reduced Schiff base as potential chemotherapeutic agents

Current and future potential of metallo drugs: Revisiting DNA-binding of metal containing molecules and their diverse mechanism of action

Design, synthesis and characterization of novel chromone based-copper(ii) antitumor agents with N , N -donor ligands: comparative DNA/RNA binding profile and cytotoxicity

Comprehensive biological {DNA/RNA binding profile, cleavage &cytotoxicity activity} of structurally well-characterized chromone-appended Cu(II)(L1-3)(phen) potential anticancer drug candidates

DNA Binding Studies of Novel Copper(II) Complexes Containing l -Tryptophan as Chiral Auxiliary: In Vitro Antitumor Activity of Cu−Sn 2 Complex in Human Neuroblastoma Cells

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