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In vitro metabolism of simvastatin in humans [SBT]identification of metabolizing enzymes and effect of the drug on hepatic P450s

Drug metabolism and disposition, 1997-10, Vol.25 (10), p.1191

1997

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Identification of cytochrome P4503A4 as the major enzyme responsible for the metabolism of ivermectin by human liver microsomes

Xenobiotica, 1998, Vol.28 (3), p.313-321

1998

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Metabolic profiles of montelukast sodium (Singulair), a potent cysteinyl leukotriene1 receptor antagonist, in human plasma and bile

Drug metabolism and disposition, 1997-11, Vol.25 (11), p.1282

1997

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Metabolites of L-735,524, a potent HIV-1 protease inhibitor, in human urine

Drug metabolism and disposition, 1995-02, Vol.23 (2), p.266

1995

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Characterization of 2‘-Deoxycytidine Adducts Derived from 4-Oxo-2-nonenal, a Novel Lipid Peroxidation Product

Chemical research in toxicology, 2003-07, Vol.16 (7), p.893-900

2003

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Characterization of methyltransferase and hydroxylase genes involved in the biosynthesis of the immunosuppressants FK506 and FK520

Journal of Bacteriology, 1996-09, Vol.178 (17), p.5243-5248

1996

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Pharmacokinetics and metabolism of a RAS farnesyl transferase inhibitor in rats and dogs: in vitro-in vivo correlation

Drug metabolism and disposition, 2001-12, Vol.29 (12), p.1578

2001

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A Novel Lipid Hydroperoxide-Derived Modification to Arginine

Chemical research in toxicology, 2003-12, Vol.16 (12), p.1598-1605

2003

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Metabolites of caspofungin acetate, a potent antifungal agent, in human plasma and urine

Drug metabolism and disposition, 2000-11, Vol.28 (11), p.1274

2000

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Disposition and metabolism of finasteride in dogs

Drug metabolism and disposition, 1997-01, Vol.25 (1), p.100

1997

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Metabolism of MK-499, a class III antiarrhythmic agent, in rats and dogs

Drug metabolism and disposition, 1998-05, Vol.26 (5), p.388

1998

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Purification and identification of dTDP-oleandrose, the precursor of the oleandrose units of the avermectins

The Journal of biological chemistry, 1990-10, Vol.265 (28), p.16965-16970

1990

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Chemical and Biological Characterization of Two FK506 Analogs Produced by Targeted Gene Disruption in Streptomyces sp. MA6548

The Journal of Antibiotics, 1997/05/25, Vol.50(5), pp.418-423

1997

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Metabolism of 3-[2-(benzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridin-2 (1H)-one (L-696,229), an HIV-1 reverse transcriptase inhibitor, by rat liver slices and in humans

Drug metabolism and disposition, 1994-03, Vol.22 (2), p.200

1994

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Metabolic disposition of ivermectin in tissues of cattle, sheep, and rats

Drug metabolism and disposition, 1986-09, Vol.14 (5), p.590

1986

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Metabolism of a new HIV-1 reverse transcriptase inhibitor, 3-[2-(benzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridin-2(1H)-one (L-696,229), in rat and liver slices

Drug metabolism and disposition, 1992-11, Vol.20 (6), p.869

1992

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Avermectins. Structure determination

Journal of the American Chemical Society, 1981-07, Vol.103 (14), p.4216-4221

1981

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Evidence for a 1,2-hydride shift in the microsomal metabolism of the heterocycle L-158,338, a nonpeptide angiotensin II receptor antagonist

Drug metabolism and disposition, 1993-07, Vol.21 (4), p.670

1993

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Metabolism of lovastatin by rat and human liver microsomes in vitro

Drug metabolism and disposition, 1988-09, Vol.16 (5), p.678

1988

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BIOSYNTHESIS OF FLUOROTHREONINE AND FLUOROACETIC: ACID BY THE THIENAMYCIN PRODUCER, STREPTOMYCES CATTLEYA

The Journal of Antibiotics, 1986, Vol.39(2), pp.259-265

1986

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Farnesol-derived Dicarboxylic Acids in the Urine of Animals Treated with Zaragozic Acid A or with Farnesol

The Journal of biological chemistry, 1997-04, Vol.272 (14), p.9197-9203

1997

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Disposition and metabolism of (+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d] cyclohepten-5,10-imine in rats, dogs, and monkeys

Drug metabolism and disposition, 1983-01, Vol.11 (1), p.54

1983

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Photodegradation of Emamectin Benzoate in Aqueous Solutions

Journal of agricultural and food chemistry, 1998-03, Vol.46 (3), p.1181-1191

1998

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Cyclization and cycloaddition of 1-cinnamylidene-5-phenyl-3-oxopyrazolidinium ylide

Tetrahedron letters, 1992-08, Vol.33 (33), p.4679-4682

1992

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Biotransformation of Finasteride (MK-0906) by Selenastrum capricornutum (Green Algae)

Annals of the New York Academy of Sciences, 1994-11, Vol.745 (1), p.51-60

1994

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In vitro metabolism of simvastatin in humans [SBT]identification of metabolizing enzymes and effect of the drug on hepatic P450s

Identification of cytochrome P4503A4 as the major enzyme responsible for the metabolism of ivermectin by human liver microsomes

Metabolic profiles of montelukast sodium (Singulair), a potent cysteinyl leukotriene1 receptor antagonist, in human plasma and bile

Metabolites of L-735,524, a potent HIV-1 protease inhibitor, in human urine

Characterization of 2‘-Deoxycytidine Adducts Derived from 4-Oxo-2-nonenal, a Novel Lipid Peroxidation Product

Characterization of methyltransferase and hydroxylase genes involved in the biosynthesis of the immunosuppressants FK506 and FK520

Pharmacokinetics and metabolism of a RAS farnesyl transferase inhibitor in rats and dogs: in vitro-in vivo correlation

A Novel Lipid Hydroperoxide-Derived Modification to Arginine

Metabolites of caspofungin acetate, a potent antifungal agent, in human plasma and urine

Disposition and metabolism of finasteride in dogs

Metabolism of MK-499, a class III antiarrhythmic agent, in rats and dogs

Purification and identification of dTDP-oleandrose, the precursor of the oleandrose units of the avermectins

Chemical and Biological Characterization of Two FK506 Analogs Produced by Targeted Gene Disruption in Streptomyces sp. MA6548

Metabolism of 3-[2-(benzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridin-2 (1H)-one (L-696,229), an HIV-1 reverse transcriptase inhibitor, by rat liver slices and in humans

Metabolic disposition of ivermectin in tissues of cattle, sheep, and rats

Metabolism of a new HIV-1 reverse transcriptase inhibitor, 3-[2-(benzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridin-2(1H)-one (L-696,229), in rat and liver slices

Avermectins. Structure determination

Evidence for a 1,2-hydride shift in the microsomal metabolism of the heterocycle L-158,338, a nonpeptide angiotensin II receptor antagonist

Metabolism of lovastatin by rat and human liver microsomes in vitro

BIOSYNTHESIS OF FLUOROTHREONINE AND FLUOROACETIC: ACID BY THE THIENAMYCIN PRODUCER, STREPTOMYCES CATTLEYA

Farnesol-derived Dicarboxylic Acids in the Urine of Animals Treated with Zaragozic Acid A or with Farnesol

Disposition and metabolism of (+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d] cyclohepten-5,10-imine in rats, dogs, and monkeys

Photodegradation of Emamectin Benzoate in Aqueous Solutions

Cyclization and cycloaddition of 1-cinnamylidene-5-phenyl-3-oxopyrazolidinium ylide

Biotransformation of Finasteride (MK-0906) by Selenastrum capricornutum (Green Algae)

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