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Single-Cell Analysis of Human Pancreas Reveals Transcriptional Signatures of Aging and Somatic Mutation Patterns

Cell, 2017-10, Vol.171 (2), p.321-330.e14

2017

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Gene Regulatory Networks Governing Pancreas Development

Developmental cell, 2013-04, Vol.25 (1), p.5-13

2013

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PancrESS - a meta-analysis resource for understanding cell-type specific expression in the human pancreas

BMC genomics, 2024-01, Vol.25 (1), p.76-12, Article 76

2024

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Age-Dependent Pancreatic Gene Regulation Reveals Mechanisms Governing Human β Cell Function

Cell metabolism, 2016-05, Vol.23 (5), p.909-920

2016

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Diet-Induced Developmental Acceleration Independent of TOR and Insulin in C. elegans

Cell, 2013-03, Vol.153 (1), p.240-252

2013

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Single-cell transcriptome and accessible chromatin dynamics during endocrine pancreas development

Proceedings of the National Academy of Sciences - PNAS, 2022-06, Vol.119 (26), p.e2201267119

2022

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A radial axis defined by semaphorin-to-neuropilin signaling controls pancreatic islet morphogenesis

Development (Cambridge), 2017-10, Vol.144 (20), p.3744-3754

2017

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Integration of Metabolic and Gene Regulatory Networks Modulates the C. elegans Dietary Response

Cell, 2013-03, Vol.153 (1), p.253-266

2013

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An integrated cell purification and genomics strategy reveals multiple regulators of pancreas development

PLoS genetics, 2014-10, Vol.10 (10), p.e1004645-e1004645

2014

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Editorial: Epigenetics of Glucose Homeostasis

Frontiers in endocrinology (Lausanne), 2022-04, Vol.13, p.889189-889189

2022

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Hippo pathway-mediated YAP1/TAZ inhibition is essential for proper pancreatic endocrine specification and differentiation

eLife, 2024-07, Vol.13

2024

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Pathways to clinical CLARITY: volumetric analysis of irregular, soft, and heterogeneous tissues in development and disease

Scientific reports, 2017-07, Vol.7 (1), p.5899-16, Article 5899

2017

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A Chromatin Basis for Cell Lineage and Disease Risk in the Human Pancreas

Cell systems, 2018-09, Vol.7 (3), p.310-322.e4

2018

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Transcription Factor Activity Mapping of a Tissue-Specific In Vivo Gene Regulatory Network

Cell systems, 2015-08, Vol.1 (2), p.152-162

2015

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Functional modularity of nuclear hormone receptors in a Caenorhabditis elegans metabolic gene regulatory network

Molecular systems biology, 2010-05, Vol.6 (1), p.367-n/a

2010

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Cell type- and transcription-independent spatial proximity between enhancers and promoters

Molecular biology of the cell, 2024-07, Vol.35 (7), p.ar96

2024

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A Transcriptionally Distinct Subpopulation of Healthy Acinar Cells Exhibit Features of Pancreatic Progenitors and PDAC

Cancer research (Chicago, Ill.), 2021-08, Vol.81 (15), p.3958-3970

2021

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Matrix and Steiner-triple-system smart pooling assays for high-performance transcription regulatory network mapping

Nature methods, 2007-08, Vol.4 (8), p.659-664

2007

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Integration of Metabolic and Gene Regulatory Networks Modulates the C. elegans Dietary Response

Cell, 2013-06, Vol.153 (6), p.1406-1407

2013

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The C. elegans Snail homolog CES-1 can activate gene expression in vivo and share targets with bHLH transcription factors

Nucleic acids research, 2009-06, Vol.37 (11), p.3689-3698

2009

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Gene-centered regulatory networks

Briefings in functional genomics, 2010-01, Vol.9 (1), p.4-12

2010

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Abstract A018: The functional characterization of pancreatic ductal adenocarcinoma GWAS risk variants in primary pancreatic cells – A pilot study

Cancer research (Chicago, Ill.), 2024-09, Vol.84 (17_Supplement_2), p.A018-A018

2024

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Abstract 1475: Uncovering the functional variants and target genes of the 7q32 pancreatic cancer risk locus

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.1475-1475

2022

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Single-Cell Analysis of Human Pancreas Reveals Transcriptional Signatures of Aging and Somatic Mutation Patterns

Gene Regulatory Networks Governing Pancreas Development

PancrESS - a meta-analysis resource for understanding cell-type specific expression in the human pancreas

Age-Dependent Pancreatic Gene Regulation Reveals Mechanisms Governing Human β Cell Function

Diet-Induced Developmental Acceleration Independent of TOR and Insulin in C. elegans

Aggressive PDACs Show Hypomethylation of Repetitive Elements and the Execution of an Intrinsic IFN Program Linked to a Ductal Cell of Origin

Single-cell transcriptome and accessible chromatin dynamics during endocrine pancreas development

A radial axis defined by semaphorin-to-neuropilin signaling controls pancreatic islet morphogenesis

Integration of Metabolic and Gene Regulatory Networks Modulates the C. elegans Dietary Response

An integrated cell purification and genomics strategy reveals multiple regulators of pancreas development

Editorial: Epigenetics of Glucose Homeostasis

Hippo pathway-mediated YAP1/TAZ inhibition is essential for proper pancreatic endocrine specification and differentiation

Pathways to clinical CLARITY: volumetric analysis of irregular, soft, and heterogeneous tissues in development and disease

A Chromatin Basis for Cell Lineage and Disease Risk in the Human Pancreas

Transcription Factor Activity Mapping of a Tissue-Specific In Vivo Gene Regulatory Network

Functional modularity of nuclear hormone receptors in a Caenorhabditis elegans metabolic gene regulatory network

Cell type- and transcription-independent spatial proximity between enhancers and promoters

A Transcriptionally Distinct Subpopulation of Healthy Acinar Cells Exhibit Features of Pancreatic Progenitors and PDAC

Matrix and Steiner-triple-system smart pooling assays for high-performance transcription regulatory network mapping

The Methyltransferases METTL7A and METTL7B Confer Resistance to Thiol-Based Histone Deacetylase Inhibitors

Integration of Metabolic and Gene Regulatory Networks Modulates the C. elegans Dietary Response

The C. elegans Snail homolog CES-1 can activate gene expression in vivo and share targets with bHLH transcription factors

Gene-centered regulatory networks

Abstract A018: The functional characterization of pancreatic ductal adenocarcinoma GWAS risk variants in primary pancreatic cells – A pilot study

Abstract 1475: Uncovering the functional variants and target genes of the 7q32 pancreatic cancer risk locus

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