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Mitochondrial Dynamics — Mitochondrial Fission and Fusion in Human Diseases

The New England journal of medicine, 2013-12, Vol.369 (23), p.2236-2251

2013

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Relevant Issues in the Pathology and Pathobiology of Pulmonary Hypertension

Journal of the American College of Cardiology, 2013-12, Vol.62 (25), p.D4-D12

2013

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The role of Drp1 adaptor proteins MiD49 and MiD51 in mitochondrial fission: implications for human disease

Clinical science (1979), 2016-11, Vol.130 (21), p.1861-1874

2016

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Acquired Mitochondrial Abnormalities, Including Epigenetic Inhibition of Superoxide Dismutase 2, in Pulmonary Hypertension and Cancer: Therapeutic Implications

Advances in experimental medicine and biology, 2016, Vol.903, p.29-53

2016

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Standards and Methodological Rigor in Pulmonary Arterial Hypertension Preclinical and Translational Research

Circulation research, 2018-03, Vol.122 (7), p.1021-1032

2018

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Dynamin‐related protein 1 (Drp1)‐mediated diastolic dysfunction in myocardial ischemia‐reperfusion injury: therapeutic benefits of Drp1 inhibition to reduce mitochondrial fission

The FASEB journal, 2014-01, Vol.28 (1), p.316-326

2014

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Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer

The FASEB journal, 2012-05, Vol.26 (5), p.2175-2186

2012

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SIRT3 Deacetylates and Activates OPA1 To Regulate Mitochondrial Dynamics during Stress

Molecular and Cellular Biology, 2014-03, Vol.34 (5), p.807-819

2014

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MicroRNA-138 and MicroRNA-25 Down-regulate Mitochondrial Calcium Uniporter, Causing the Pulmonary Arterial Hypertension Cancer Phenotype

American journal of respiratory and critical care medicine, 2017-02, Vol.195 (4), p.515-529

2017

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Mitochondrial fission links ECM mechanotransduction to metabolic redox homeostasis and metastatic chemotherapy resistance

Nature cell biology, 2022-02, Vol.24 (2), p.168-180

2022

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Ndufs2, a Core Subunit of Mitochondrial Complex I, Is Essential for Acute Oxygen-Sensing and Hypoxic Pulmonary Vasoconstriction

Circulation research, 2019-06, Vol.124 (12), p.1727-1746

2019

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Right Ventricular Adaptation and Failure in Pulmonary Arterial Hypertension

Canadian journal of cardiology, 2015-04, Vol.31 (4), p.391-406

2015

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Identification of novel dynamin‐related protein 1 (Drp1) GTPase inhibitors: Therapeutic potential of Drpitor1 and Drpitor1a in cancer and cardiac ischemia‐reperfusion injury

The FASEB journal, 2020-01, Vol.34 (1), p.1447-1464

2020

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Mitochondrial metabolic adaptation in right ventricular hypertrophy and failure

Journal of molecular medicine (Berlin, Germany), 2010-10, Vol.88 (10), p.1011-1020

2010

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Riociguat for Pulmonary Hypertension — A Glass Half Full

The New England journal of medicine, 2013-07, Vol.369 (4), p.386-388

Archer, Stephen L

2013

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Dynamin-Related Protein 1–Mediated Mitochondrial Mitotic Fission Permits Hyperproliferation of Vascular Smooth Muscle Cells and Offers a Novel Therapeutic Target in Pulmonary Hypertension

Circulation research, 2012-05, Vol.110 (11), p.1484-1497

2012

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PINK1‐induced phosphorylation of mitofusin 2 at serine 442 causes its proteasomal degradation and promotes cell proliferation in lung cancer and pulmonary arterial hypertension

The FASEB journal, 2021-08, Vol.35 (8), p.e21771-n/a

2021

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Airway Delivery of Mesenchymal Stem Cells Prevents Arrested Alveolar Growth in Neonatal Lung Injury in Rats

American journal of respiratory and critical care medicine, 2009-12, Vol.180 (11), p.1131-1142

2009

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Cardiac glutaminolysis: a maladaptive cancer metabolism pathway in the right ventricle in pulmonary hypertension

Journal of molecular medicine (Berlin, Germany), 2013-10, Vol.91 (10), p.1185-1197

2013

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The Herpes Simplex Virus pUL16 and pUL21 Proteins Prevent Capsids from Docking at Nuclear Pore Complexes

PLoS pathogens, 2023-12, Vol.19 (12), p.e1011832-e1011832

2023

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Cellular and Molecular Basis of Pulmonary Arterial Hypertension

Journal of the American College of Cardiology, 2009-06, Vol.54 (1), p.S20-S31

2009

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Therapeutic inhibition of fatty acid oxidation in right ventricular hypertrophy: exploiting Randle’s cycle

Journal of molecular medicine (Berlin, Germany), 2012-01, Vol.90 (1), p.31-43

2012

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Critical Genomic Networks and Vasoreactive Variants in Idiopathic Pulmonary Arterial Hypertension

American journal of respiratory and critical care medicine, 2016-08, Vol.194 (4), p.464-475

2016

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nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted

Proceedings of the National Academy of Sciences - PNAS, 2007-07, Vol.104 (27), p.11418-11423

2007

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Transcriptomic Signature of Right Ventricular Failure in Experimental Pulmonary Arterial Hypertension: Deep Sequencing Demonstrates Mitochondrial, Fibrotic, Inflammatory and Angiogenic Abnormalities

International journal of molecular sciences, 2018-09, Vol.19 (9), p.2730

2018

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Mitochondrial Dynamics — Mitochondrial Fission and Fusion in Human Diseases

Relevant Issues in the Pathology and Pathobiology of Pulmonary Hypertension

The role of Drp1 adaptor proteins MiD49 and MiD51 in mitochondrial fission: implications for human disease

Acquired Mitochondrial Abnormalities, Including Epigenetic Inhibition of Superoxide Dismutase 2, in Pulmonary Hypertension and Cancer: Therapeutic Implications

Standards and Methodological Rigor in Pulmonary Arterial Hypertension Preclinical and Translational Research

Dynamin‐related protein 1 (Drp1)‐mediated diastolic dysfunction in myocardial ischemia‐reperfusion injury: therapeutic benefits of Drp1 inhibition to reduce mitochondrial fission

Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer

SIRT3 Deacetylates and Activates OPA1 To Regulate Mitochondrial Dynamics during Stress

MicroRNA-138 and MicroRNA-25 Down-regulate Mitochondrial Calcium Uniporter, Causing the Pulmonary Arterial Hypertension Cancer Phenotype

Mitochondrial fission links ECM mechanotransduction to metabolic redox homeostasis and metastatic chemotherapy resistance

Ndufs2, a Core Subunit of Mitochondrial Complex I, Is Essential for Acute Oxygen-Sensing and Hypoxic Pulmonary Vasoconstriction

Right Ventricular Adaptation and Failure in Pulmonary Arterial Hypertension

Identification of novel dynamin‐related protein 1 (Drp1) GTPase inhibitors: Therapeutic potential of Drpitor1 and Drpitor1a in cancer and cardiac ischemia‐reperfusion injury

Mitochondrial metabolic adaptation in right ventricular hypertrophy and failure

Riociguat for Pulmonary Hypertension — A Glass Half Full

Dynamin-Related Protein 1–Mediated Mitochondrial Mitotic Fission Permits Hyperproliferation of Vascular Smooth Muscle Cells and Offers a Novel Therapeutic Target in Pulmonary Hypertension

PINK1‐induced phosphorylation of mitofusin 2 at serine 442 causes its proteasomal degradation and promotes cell proliferation in lung cancer and pulmonary arterial hypertension

Airway Delivery of Mesenchymal Stem Cells Prevents Arrested Alveolar Growth in Neonatal Lung Injury in Rats

Cardiac glutaminolysis: a maladaptive cancer metabolism pathway in the right ventricle in pulmonary hypertension

The Herpes Simplex Virus pUL16 and pUL21 Proteins Prevent Capsids from Docking at Nuclear Pore Complexes

Cellular and Molecular Basis of Pulmonary Arterial Hypertension

Therapeutic inhibition of fatty acid oxidation in right ventricular hypertrophy: exploiting Randle’s cycle

Critical Genomic Networks and Vasoreactive Variants in Idiopathic Pulmonary Arterial Hypertension

nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted

Transcriptomic Signature of Right Ventricular Failure in Experimental Pulmonary Arterial Hypertension: Deep Sequencing Demonstrates Mitochondrial, Fibrotic, Inflammatory and Angiogenic Abnormalities

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