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Soluble Guanylate Cyclase: A New Therapeutic Target for Pulmonary Arterial Hypertension and Chronic Thromboembolic Pulmonary Hypertension

Clinical pharmacology and therapeutics, 2015-01, Vol.97 (1), p.88-102

2015

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MECHANISMS OF DISEASE Acute Oxygen-Sensing Mechanisms

The New England journal of medicine, 2005-11, Vol.353 (19), p.2042-2055

2005

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Vascular endothelial growth factor gene therapy increases survival, promotes lung angiogenesis, and prevents alveolar damage in hyperoxia-induced lung injury : Evidence that angiogenesis participates in alveolarization

Circulation (New York, N.Y.), 2005-10, Vol.112 (16), p.2477-2486

2005

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Repurposing Medications for Treatment of Pulmonary Arterial Hypertension: What's Old Is New Again

Journal of the American Heart Association, 2019-01, Vol.8 (1), p.e011343-e011343

2019

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Cellular and molecular pathobiology of pulmonary arterial hypertension

Journal of the American College of Cardiology, 2004-06, Vol.43 (12), p.S13-S24

2004

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Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension

The Journal of clinical investigation, 2005-06, Vol.115 (6), p.1479-1491

2005

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Long-term treatment with oral sildenafil is safe and improves functional capacity and hemodynamics in patients with pulmonary arterial hypertension

Circulation (New York, N.Y.), 2003-10, Vol.108 (17), p.2066-2069

2003

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Mining the Plasma Proteome for Insights into the Molecular Pathology of Pulmonary Arterial Hypertension

American journal of respiratory and critical care medicine, 2022-06, Vol.205 (12), p.1449-1460

2022

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A Dosing/Cross-Development Study of the Multikinase Inhibitor Sorafenib in Patients With Pulmonary Arterial Hypertension

Clinical pharmacology and therapeutics, 2010-03, Vol.87 (3), p.303-310

2010

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Hypoxic pulmonary vasoconstriction: redox regulation of O 2-sensitive K + channels by a mitochondrial O 2-sensor in resistance artery smooth muscle cells

Journal of molecular and cellular cardiology, 2004-12, Vol.37 (6), p.1119-1136

2004

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Diversity in Mitochondrial Function Explains Differences in Vascular Oxygen Sensing

Circulation research, 2002-06, Vol.90 (12), p.1307-1315

2002

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Decreased platelet nitric oxide synthase activity and plasma nitric oxide metabolites in major depressive disorder

Biological psychiatry (1969), 2004-07, Vol.56 (2), p.129-134

2004

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Preferential Expression and Function of Voltage-Gated, O 2 -Sensitive K + Channels in Resistance Pulmonary Arteries Explains Regional Heterogeneity in Hypoxic Pulmonary Vasoconstriction: Ionic Diversity in Smooth Muscle Cells

Circulation research, 2004-08, Vol.95 (3), p.308-318

2004

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Dichloroacetate, a metabolic modulator, prevents and reverses chronic hypoxic pulmonary hypertension in rats: Role of increased expression and activity of voltage-gated potassium channels

Circulation (New York, N.Y.), 2002-01, Vol.105 (2), p.244-250

2002

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Endothelium-derived hyperpolarizing factor in human internal mammary artery is 11,12-epoxyeicosatrienoic acid and causes relaxation by activating smooth muscle BKCa channels

Circulation (New York, N.Y.), 2003-02, Vol.107 (5), p.769-776

2003

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In Vivo Gene Transfer of the O 2 -Sensitive Potassium Channel Kv1.5 Reduces Pulmonary Hypertension and Restores Hypoxic Pulmonary Vasoconstriction in Chronically Hypoxic Rats

Circulation (New York, N.Y.), 2003-04, Vol.107 (15), p.2037-2044

2003

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An evidence-based approach to the management of pulmonary arterial hypertension

Current opinion in cardiology, 2006-07, Vol.21 (4), p.385-392

2006

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Oxygen-sensitive Kv channel gene transfer confers oxygen responsiveness to preterm rabbit and remodeled human ductus arteriosus: implications for infants with patent ductus arteriosus

Circulation (New York, N.Y.), 2004-09, Vol.110 (11), p.1372-1379

2004

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Molecular identification of the role of voltage-gated K+ channels, Kv1.5 and Kv2.1, in hypoxic pulmonary vasoconstriction and control of resting membrane potential in rat pulmonary artery myocytes

The Journal of clinical investigation, 1998-06, Vol.101 (11), p.2319-2330

1998

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The mechanism of acute hypoxic pulmonary vasoconstriction: the tale of two channels

The FASEB journal, 1995-02, Vol.9 (2), p.183-189

1995

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The neurovascular mechanism of clitoral erection: nitric oxide and cGMP‐stimulated activation of BKCa channels

The FASEB journal, 2004-09, Vol.18 (12), p.1382-1391

2004

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Pre–B-cell Colony-Enhancing Factor Regulates Vascular Smooth Muscle Maturation Through a NAD+-Dependent Mechanism: Recognition of a New Mechanism for Cell Diversity and Redox Regulation of Vascular Tone and Remodeling

Circulation research, 2005-07, Vol.97 (1), p.4-7

Archer, Stephen L

2005

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Hypoxia potentiates nitric oxide synthesis and transiently increases cytosolic calcium levels in pulmonary artery endothelial cells

The European respiratory journal, 1995-04, Vol.8 (4), p.515-522

1995

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Potassium channels and erectile dysfunction

Vascular pharmacology, 2002, Vol.38 (1), p.61-71

Archer, Stephen L

2002

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Nitric Oxide and cGMP Cause Vasorelaxation by Activation of a Charybdotoxin-Sensitive K Channel by cGMP-Dependent Protein Kinase

Proceedings of the National Academy of Sciences - PNAS, 1994-08, Vol.91 (16), p.7583-7587

1994

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Soluble Guanylate Cyclase: A New Therapeutic Target for Pulmonary Arterial Hypertension and Chronic Thromboembolic Pulmonary Hypertension

MECHANISMS OF DISEASE Acute Oxygen-Sensing Mechanisms

Vascular endothelial growth factor gene therapy increases survival, promotes lung angiogenesis, and prevents alveolar damage in hyperoxia-induced lung injury : Evidence that angiogenesis participates in alveolarization

Repurposing Medications for Treatment of Pulmonary Arterial Hypertension: What's Old Is New Again

Cellular and molecular pathobiology of pulmonary arterial hypertension

Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension

Long-term treatment with oral sildenafil is safe and improves functional capacity and hemodynamics in patients with pulmonary arterial hypertension

Mining the Plasma Proteome for Insights into the Molecular Pathology of Pulmonary Arterial Hypertension

A Dosing/Cross-Development Study of the Multikinase Inhibitor Sorafenib in Patients With Pulmonary Arterial Hypertension

Hypoxic pulmonary vasoconstriction: redox regulation of O 2-sensitive K + channels by a mitochondrial O 2-sensor in resistance artery smooth muscle cells

Diversity in Mitochondrial Function Explains Differences in Vascular Oxygen Sensing

Decreased platelet nitric oxide synthase activity and plasma nitric oxide metabolites in major depressive disorder

Preferential Expression and Function of Voltage-Gated, O 2 -Sensitive K + Channels in Resistance Pulmonary Arteries Explains Regional Heterogeneity in Hypoxic Pulmonary Vasoconstriction: Ionic Diversity in Smooth Muscle Cells

Dichloroacetate, a metabolic modulator, prevents and reverses chronic hypoxic pulmonary hypertension in rats: Role of increased expression and activity of voltage-gated potassium channels

Endothelium-derived hyperpolarizing factor in human internal mammary artery is 11,12-epoxyeicosatrienoic acid and causes relaxation by activating smooth muscle BKCa channels

In Vivo Gene Transfer of the O 2 -Sensitive Potassium Channel Kv1.5 Reduces Pulmonary Hypertension and Restores Hypoxic Pulmonary Vasoconstriction in Chronically Hypoxic Rats

An evidence-based approach to the management of pulmonary arterial hypertension

Oxygen-sensitive Kv channel gene transfer confers oxygen responsiveness to preterm rabbit and remodeled human ductus arteriosus: implications for infants with patent ductus arteriosus

Molecular identification of the role of voltage-gated K+ channels, Kv1.5 and Kv2.1, in hypoxic pulmonary vasoconstriction and control of resting membrane potential in rat pulmonary artery myocytes

The mechanism of acute hypoxic pulmonary vasoconstriction: the tale of two channels

The neurovascular mechanism of clitoral erection: nitric oxide and cGMP‐stimulated activation of BKCa channels

Pre–B-cell Colony-Enhancing Factor Regulates Vascular Smooth Muscle Maturation Through a NAD+-Dependent Mechanism: Recognition of a New Mechanism for Cell Diversity and Redox Regulation of Vascular Tone and Remodeling

Hypoxia potentiates nitric oxide synthesis and transiently increases cytosolic calcium levels in pulmonary artery endothelial cells

Potassium channels and erectile dysfunction

Nitric Oxide and cGMP Cause Vasorelaxation by Activation of a Charybdotoxin-Sensitive K Channel by cGMP-Dependent Protein Kinase

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