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Soluble Guanylate Cyclase: A New Therapeutic Target for Pulmonary Arterial Hypertension and Chronic Thromboembolic Pulmonary Hypertension

Clinical pharmacology and therapeutics, 2015-01, Vol.97 (1), p.88-102

2015

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Rodent models of pulmonary hypertension: harmonisation with the world health organisation's categorisation of human PH

International journal of clinical practice (Esher), 2011-08, Vol.65 (s172), p.15-34

2011

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A Dosing/Cross-Development Study of the Multikinase Inhibitor Sorafenib in Patients With Pulmonary Arterial Hypertension

Clinical pharmacology and therapeutics, 2010-03, Vol.87 (3), p.303-310

2010

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Angiogenic gene therapy in patients with nonrevascularizable ischemic heart disease : a phase 2 randomized, controlled trial of AdVEGF121 (AdVEGF121) versus maximum medical treatment

Gene therapy, 2006-11, Vol.13 (21), p.1503-1511

2006

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Survival in pulmonary arterial hypertension: a reappraisal of the NIH risk stratification equation

The European respiratory journal, 2010-05, Vol.35 (5), p.1079-1087

2010

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Alterations in a redox oxygen sensing mechanism in chronic hypoxia

Journal of applied physiology (1985), 2001-06, Vol.90 (6), p.2249-2256

2001

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Molecular identification of the role of voltage-gated K+ channels, Kv1.5 and Kv2.1, in hypoxic pulmonary vasoconstriction and control of resting membrane potential in rat pulmonary artery myocytes

The Journal of clinical investigation, 1998-06, Vol.101 (11), p.2319-2330

1998

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A Redox-Based O2 Sensor in Rat Pulmonary Vasculature

Circulation research, 1993-12, Vol.73 (6), p.1100-1112

1993

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Direct role for potassium channel inhibition in hypoxic pulmonary vasoconstriction

American Journal of Physiology: Cell Physiology, 1992-04, Vol.262 (4), p.C882-C890

1992

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Nitric Oxide and cGMP Cause Vasorelaxation by Activation of a Charybdotoxin-Sensitive K Channel by cGMP-Dependent Protein Kinase

Proceedings of the National Academy of Sciences - PNAS, 1994-08, Vol.91 (16), p.7583-7587

1994

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Impairment of hypoxic pulmonary vasoconstriction in mice lacking the voltage‐gated potassium channel Kv1.5

The FASEB journal, 2001-08, Vol.15 (10), p.1801-1803

2001

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Differential Distribution of Electrophysiologically Distinct Myocytes in Conduit and Resistance Arteries Determines Their Response to Nitric Oxide and Hypoxia

Circulation research, 1996-03, Vol.78 (3), p.431-442

1996

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Anorexic agents aminorex, fenfluramine, and dexfenfluramine inhibit potassium current in rat pulmonary vascular smooth muscle and cause pulmonary vasoconstriction

Circulation (New York, N.Y.), 1996-11, Vol.94 (9), p.2216-2220

1996

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Angiogenic gene therapy in patients with nonrevascularizable ischemic heart disease: a phase 2 randomized, controlled trial of AdVEGF (AdVEGF121) versus maximum medical treatment

Gene therapy, 2006-11, Vol.13 (21), p.1503-1511

2006

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Long-term treatment with oral sildenafil is safe and improves functional capacity and hemodynamics in patients with pulmonary arterial hypertension

Circulation (New York, N.Y.), 2003-10, Vol.108 (17), p.2066-2069

2003

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Hypoxia potentiates nitric oxide synthesis and transiently increases cytosolic calcium levels in pulmonary artery endothelial cells

The European respiratory journal, 1995-04, Vol.8 (4), p.515-522

1995

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A Role for Potassium Channels in Smooth Muscle Cells and Platelets in the Etiology of Primary Pulmonary Hypertension

Chest, 1998-09, Vol.114 (3), p.200S-204S

1998

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Oxygen-induced constriction of rabbit ductus arteriosus occurs via inhibition of a 4-aminopyridine-, voltage-sensitive potassium channel

The Journal of clinical investigation, 1996-11, Vol.98 (9), p.1959-1965

1996

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O2 Sensing Is Preserved in Mice Lacking the gp91 Phox Subunit of NADPH Oxidase

Proceedings of the National Academy of Sciences - PNAS, 1999-07, Vol.96 (14), p.7944-7949

1999

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Chronic EDRF inhibition and hypoxia: effects on pulmonary circulation and systemic blood pressure

Journal of applied physiology (1985), 1993-10, Vol.75 (4), p.1748

1993

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Association of dietary fish and n-3 fatty acid intake with hemostatic factors in the coronary artery risk development in young adults (CARDIA) study

Arteriosclerosis, thrombosis, and vascular biology, 1998-07, Vol.18 (7), p.1119

1998

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Diphenyleneiodonium inhibits both potassium and calcium currents in isolated pulmonary artery smooth muscle cells

Journal of applied physiology (1985), 1994-06, Vol.76 (6), p.2611

1994

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Enhanced Chemiluminescence as a Measure of Oxygen-Derived Free Radical Generation During Ischemia and Reperfusion

Circulation research, 1990-12, Vol.67 (6), p.1453-1461

1990

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Origins of Breath Nitric Oxide in Humans

Chest, 1996-10, Vol.110 (4), p.930-938

1996

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Hypoxic pulmonary vasoconstriction is enhanced by inhibition of the synthesis of an endothelium derived relaxing factor

Biochemical and biophysical research communications, 1989-11, Vol.164 (3), p.1198-1205

1989

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Soluble Guanylate Cyclase: A New Therapeutic Target for Pulmonary Arterial Hypertension and Chronic Thromboembolic Pulmonary Hypertension

Rodent models of pulmonary hypertension: harmonisation with the world health organisation's categorisation of human PH

A Dosing/Cross-Development Study of the Multikinase Inhibitor Sorafenib in Patients With Pulmonary Arterial Hypertension

Angiogenic gene therapy in patients with nonrevascularizable ischemic heart disease : a phase 2 randomized, controlled trial of AdVEGF121 (AdVEGF121) versus maximum medical treatment

Survival in pulmonary arterial hypertension: a reappraisal of the NIH risk stratification equation

Alterations in a redox oxygen sensing mechanism in chronic hypoxia

Molecular identification of the role of voltage-gated K+ channels, Kv1.5 and Kv2.1, in hypoxic pulmonary vasoconstriction and control of resting membrane potential in rat pulmonary artery myocytes

A Redox-Based O2 Sensor in Rat Pulmonary Vasculature

Direct role for potassium channel inhibition in hypoxic pulmonary vasoconstriction

Nitric Oxide and cGMP Cause Vasorelaxation by Activation of a Charybdotoxin-Sensitive K Channel by cGMP-Dependent Protein Kinase

Impairment of hypoxic pulmonary vasoconstriction in mice lacking the voltage‐gated potassium channel Kv1.5

Differential Distribution of Electrophysiologically Distinct Myocytes in Conduit and Resistance Arteries Determines Their Response to Nitric Oxide and Hypoxia

Anorexic agents aminorex, fenfluramine, and dexfenfluramine inhibit potassium current in rat pulmonary vascular smooth muscle and cause pulmonary vasoconstriction

Angiogenic gene therapy in patients with nonrevascularizable ischemic heart disease: a phase 2 randomized, controlled trial of AdVEGF (AdVEGF121) versus maximum medical treatment

Long-term treatment with oral sildenafil is safe and improves functional capacity and hemodynamics in patients with pulmonary arterial hypertension

Hypoxia potentiates nitric oxide synthesis and transiently increases cytosolic calcium levels in pulmonary artery endothelial cells

A Role for Potassium Channels in Smooth Muscle Cells and Platelets in the Etiology of Primary Pulmonary Hypertension

Oxygen-induced constriction of rabbit ductus arteriosus occurs via inhibition of a 4-aminopyridine-, voltage-sensitive potassium channel

O2 Sensing Is Preserved in Mice Lacking the gp91 Phox Subunit of NADPH Oxidase

Chronic EDRF inhibition and hypoxia: effects on pulmonary circulation and systemic blood pressure

Association of dietary fish and n-3 fatty acid intake with hemostatic factors in the coronary artery risk development in young adults (CARDIA) study

Diphenyleneiodonium inhibits both potassium and calcium currents in isolated pulmonary artery smooth muscle cells

Enhanced Chemiluminescence as a Measure of Oxygen-Derived Free Radical Generation During Ischemia and Reperfusion

Origins of Breath Nitric Oxide in Humans

Hypoxic pulmonary vasoconstriction is enhanced by inhibition of the synthesis of an endothelium derived relaxing factor

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