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Neuregulin 4 Is a Novel Marker of Beige Adipocyte Precursor Cells in Human Adipose Tissue

Frontiers in physiology, 2019-01, Vol.10, p.39-39

2019

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The relevance of EGFR, ErbB receptors and neuregulins in human adipocytes and adipose tissue in obesity

Biomedicine & pharmacotherapy, 2022-12, Vol.156, p.113972-113972, Article 113972

2022

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Serum neuregulin 4 is negatively correlated with insulin sensitivity in humans and impairs mitochondrial respiration in HepG2 cells

Frontiers in physiology, 2022-09, Vol.13, p.950791-950791

2022

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Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease

Nature reviews. Drug discovery, 2009-02, Vol.8 (2), p.139-152

2009

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Role of the HIF oxygen sensing pathway in cell defense and proliferation through the control of amino acid metabolism

Biochimica et biophysica acta. Molecular cell research, 2020-09, Vol.1867 (9), p.118733-118733, Article 118733

2020

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Substrate fate in activated macrophages: a comparison between innate, classic, and alternative activation

The Journal of immunology (1950), 2010-07, Vol.185 (1), p.605-614

2010

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Oxygen Sensors at the Crossroad of Metabolism

Cell metabolism, 2009-01, Vol.9 (1), p.11-22

2009

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Molecular Pathways: Hypoxia Response in Immune Cells Fighting or Promoting Cancer

Clinical cancer research, 2012-03, Vol.18 (5), p.1207-1213

2012

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Role of Mitochondrial Complex IV in Age-Dependent Obesity

Cell reports (Cambridge), 2016-09, Vol.16 (11), p.2991-3002

2016

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Synaptic activity‐induced glycolysis facilitates membrane lipid provision and neurite outgrowth

The EMBO journal, 2018-05, Vol.37 (9), p.n/a

2018

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Differential Contribution of N- and C-Terminal Regions of HIF1α and HIF2α to Their Target Gene Selectivity

International journal of molecular sciences, 2020-12, Vol.21 (24), p.9401

2020

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Targeting L-type amino acid transporter 1 in innate and adaptive T cells efficiently controls skin inflammation

Journal of allergy and clinical immunology, 2020-01, Vol.145 (1), p.199-214.e11

2020

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HIF1α-dependent uncoupling of glycolysis suppresses tumor cell proliferation

Cell reports (Cambridge), 2024-04, Vol.43 (4), p.114103-114103, Article 114103

2024

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Neuregulin 4 Downregulation Induces Insulin Resistance in 3T3-L1 Adipocytes through Inflammation and Autophagic Degradation of GLUT4 Vesicles

International journal of molecular sciences, 2021-11, Vol.22 (23), p.12960

2021

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Induction of the Mitochondrial NDUFA4L2 Protein by HIF-1α Decreases Oxygen Consumption by Inhibiting Complex I Activity

Cell metabolism, 2011-12, Vol.14 (6), p.768-779

2011

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Unique expression of the atypical mitochondrial subunit NDUFA4L2 in cerebral pericytes fine tunes HIF activity in response to hypoxia

Journal of cerebral blood flow and metabolism, 2023-01, Vol.43 (1), p.44-58

2023

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HIF Oxygen Sensing Pathways in Lung Biology

Biomedicines, 2018-06, Vol.6 (2), p.68

2018

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Macrophage oxygen sensing modulates antigen presentation and phagocytic functions involving IFN-gamma production through the HIF-1 alpha transcription factor

The Journal of immunology (1950), 2009-03, Vol.182 (5), p.3155-3164

2009

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HIF-2α-mediated induction of pulmonary thrombospondin-1 contributes to hypoxia-driven vascular remodelling and vasoconstriction

Cardiovascular research, 2016-01, Vol.109 (1), p.115-130

2016

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Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism

Nature genetics, 2008-02, Vol.40 (2), p.170-180

2008

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HIF2α Acts as an mTORC1 Activator through the Amino Acid Carrier SLC7A5

Molecular cell, 2012-12, Vol.48 (5), p.681-691

2012

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IL-18-induced HIF-1α in ILC3s ameliorates the inflammation of C. rodentium-induced colitis

Cell reports (Cambridge), 2023-12, Vol.42 (12), p.113508-113508, Article 113508

2023

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The HIF-1α hypoxia response in tumor-infiltrating T lymphocytes induces functional CD137 (4-1BB) for immunotherapy

Cancer discovery, 2012-07, Vol.2 (7), p.608-623

2012

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Myocardial VHL-HIF Signaling Controls an Embryonic Metabolic Switch Essential for Cardiac Maturation

Developmental cell, 2016-12, Vol.39 (6), p.724-739

2016

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Neuregulin 4 Is a Novel Marker of Beige Adipocyte Precursor Cells in Human Adipose Tissue

The relevance of EGFR, ErbB receptors and neuregulins in human adipocytes and adipose tissue in obesity

Serum neuregulin 4 is negatively correlated with insulin sensitivity in humans and impairs mitochondrial respiration in HepG2 cells

Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease

Role of the HIF oxygen sensing pathway in cell defense and proliferation through the control of amino acid metabolism

Substrate fate in activated macrophages: a comparison between innate, classic, and alternative activation

Oxygen Sensors at the Crossroad of Metabolism

Molecular Pathways: Hypoxia Response in Immune Cells Fighting or Promoting Cancer

Role of Mitochondrial Complex IV in Age-Dependent Obesity

Synaptic activity‐induced glycolysis facilitates membrane lipid provision and neurite outgrowth

Differential Contribution of N- and C-Terminal Regions of HIF1α and HIF2α to Their Target Gene Selectivity

Targeting L-type amino acid transporter 1 in innate and adaptive T cells efficiently controls skin inflammation

HIF1α-dependent uncoupling of glycolysis suppresses tumor cell proliferation

Heterozygous Deficiency of PHD2 Restores Tumor Oxygenation and Inhibits Metastasis via Endothelial Normalization

Neuregulin 4 Downregulation Induces Insulin Resistance in 3T3-L1 Adipocytes through Inflammation and Autophagic Degradation of GLUT4 Vesicles

Induction of the Mitochondrial NDUFA4L2 Protein by HIF-1α Decreases Oxygen Consumption by Inhibiting Complex I Activity

Unique expression of the atypical mitochondrial subunit NDUFA4L2 in cerebral pericytes fine tunes HIF activity in response to hypoxia

HIF Oxygen Sensing Pathways in Lung Biology

Macrophage oxygen sensing modulates antigen presentation and phagocytic functions involving IFN-gamma production through the HIF-1 alpha transcription factor

HIF-2α-mediated induction of pulmonary thrombospondin-1 contributes to hypoxia-driven vascular remodelling and vasoconstriction

Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism

HIF2α Acts as an mTORC1 Activator through the Amino Acid Carrier SLC7A5

IL-18-induced HIF-1α in ILC3s ameliorates the inflammation of C. rodentium-induced colitis

The HIF-1α hypoxia response in tumor-infiltrating T lymphocytes induces functional CD137 (4-1BB) for immunotherapy

Myocardial VHL-HIF Signaling Controls an Embryonic Metabolic Switch Essential for Cardiac Maturation

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