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Engineering organoids: a promising platform to understand biology and treat diseases

Cell death and differentiation, 2021-01, Vol.28 (1), p.1-4

Aqeilan, Rami I.

2021

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TRPM2 Mediates Neutrophil Killing of Disseminated Tumor Cells

Cancer research (Chicago, Ill.), 2018-05, Vol.78 (10), p.2680-2690

2018

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Negative Regulation of the Hippo Pathway by E3 Ubiquitin Ligase ITCH Is Sufficient to Promote Tumorigenicity

Cancer research (Chicago, Ill.), 2011-03, Vol.71 (5), p.2010-2020

2011

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Pleiotropic Functions of Tumor Suppressor WWOX in Normal and Cancer Cells

The Journal of biological chemistry, 2015-12, Vol.290 (52), p.30728-30735

2015

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Biological Functions of miR-29b Contribute to Positive Regulation of Osteoblast Differentiation

The Journal of biological chemistry, 2009-06, Vol.284 (23), p.15676-15684

2009

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Tumor Suppressor Genes within Common Fragile Sites Are Active Players in the DNA Damage Response

PLoS Genetics, 2016-12, Vol.12 (12), p.e1006436

2016

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Modeling WWOX Loss of Function in vivo : What Have We Learned?

Frontiers in oncology, 2018-10, Vol.8, p.420-420

2018

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WWOX: Its genomics, partners, and functions

Journal of cellular biochemistry, 2009-11, Vol.108 (4), p.737-745

2009

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Activation of Oncogenic Super-Enhancers Is Coupled with DNA Repair by RAD51

Cell reports (Cambridge), 2019-10, Vol.29 (3), p.560-572.e4

2019

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WWOX, the common fragile site FRA16D gene product, regulates ATM activation and the DNA damage response

Proceedings of the National Academy of Sciences - PNAS, 2014-11, Vol.111 (44), p.15612-15612

2014

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MiR-15a and miR-16-1 cluster functions in human leukemia

Proceedings of the National Academy of Sciences - PNAS, 2008-04, Vol.105 (13), p.5166-5171

2008

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Modeling genetic epileptic encephalopathies using brain organoids

EMBO molecular medicine, 2021-08, Vol.13 (8), p.e13610-n/a

2021

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MicroRNAs regulate critical genes associated with multiple myeloma pathogenesis

Proceedings of the National Academy of Sciences - PNAS, 2008-09, Vol.105 (35), p.12885-12890

2008

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Neonatal neuronal WWOX gene therapy rescues Wwox null phenotypes

EMBO molecular medicine, 2021-12, Vol.13 (12), p.e14599-n/a

2021

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miR-15 and miR-16 Induce Apoptosis by Targeting BCL2

Proceedings of the National Academy of Sciences - PNAS, 2005-09, Vol.102 (39), p.13944-13949

2005

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MicroRNA-214 promotes hepatic stellate cell activation and liver fibrosis by suppressing Sufu expression

Cell death & disease, 2018-06, Vol.9 (7), p.718-13, Article 718

2018

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RBM6 splicing factor promotes homologous recombination repair of double-strand breaks and modulates sensitivity to chemotherapeutic drugs

Nucleic acids research, 2021-11, Vol.49 (20), p.11708-11727

2021

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Altered neocortical oscillations and cellular excitability in an in vitro Wwox knockout mouse model of epileptic encephalopathy

Neurobiology of disease, 2021-12, Vol.160, p.105529-105529, Article 105529

2021

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Loss of tumor suppressor WWOX accelerates pancreatic cancer development through promotion of TGFβ/BMP2 signaling

Cell death & disease, 2022-12, Vol.13 (12), p.1074-1074, Article 1074

2022

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FHIT suppresses epithelial-mesenchymal transition (EMT) and metastasis in lung cancer through modulation of microRNAs

PLoS genetics, 2014-10, Vol.10 (10), p.e1004652-e1004652

2014

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Fhit–Fdxr interaction in the mitochondria: modulation of reactive oxygen species generation and apoptosis in cancer cells

Cell death & disease, 2019-02, Vol.10 (3), p.147-147, Article 147

2019

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Programmed DNA Damage and Physiological DSBs: Mapping, Biological Significance and Perturbations in Disease States

Cells (Basel, Switzerland), 2020-08, Vol.9 (8), p.1870

2020

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WWOX promotes osteosarcoma development via upregulation of Myc

Cell death & disease, 2024-01, Vol.15 (1), p.13-13, Article 13

2024

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Twist1-induced miR-199a-3p promotes liver fibrosis by suppressing caveolin-2 and activating TGF-β pathway

Signal transduction and targeted therapy, 2020-06, Vol.5 (1), p.75-75, Article 75

2020

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MicroRNAs/TP53 feedback circuitry in glioblastoma multiforme

Proceedings of the National Academy of Sciences - PNAS, 2012-04, Vol.109 (14), p.5316-5321

2012

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Engineering organoids: a promising platform to understand biology and treat diseases

TRPM2 Mediates Neutrophil Killing of Disseminated Tumor Cells

Negative Regulation of the Hippo Pathway by E3 Ubiquitin Ligase ITCH Is Sufficient to Promote Tumorigenicity

Pleiotropic Functions of Tumor Suppressor WWOX in Normal and Cancer Cells

Biological Functions of miR-29b Contribute to Positive Regulation of Osteoblast Differentiation

Tumor Suppressor Genes within Common Fragile Sites Are Active Players in the DNA Damage Response

Modeling WWOX Loss of Function in vivo : What Have We Learned?

WWOX: Its genomics, partners, and functions

Activation of Oncogenic Super-Enhancers Is Coupled with DNA Repair by RAD51

WWOX, the common fragile site FRA16D gene product, regulates ATM activation and the DNA damage response

MiR-15a and miR-16-1 cluster functions in human leukemia

Modeling genetic epileptic encephalopathies using brain organoids

MicroRNAs regulate critical genes associated with multiple myeloma pathogenesis

Neonatal neuronal WWOX gene therapy rescues Wwox null phenotypes

miR-15 and miR-16 Induce Apoptosis by Targeting BCL2

MicroRNA-214 promotes hepatic stellate cell activation and liver fibrosis by suppressing Sufu expression

RBM6 splicing factor promotes homologous recombination repair of double-strand breaks and modulates sensitivity to chemotherapeutic drugs

Altered neocortical oscillations and cellular excitability in an in vitro Wwox knockout mouse model of epileptic encephalopathy

Loss of tumor suppressor WWOX accelerates pancreatic cancer development through promotion of TGFβ/BMP2 signaling

FHIT suppresses epithelial-mesenchymal transition (EMT) and metastasis in lung cancer through modulation of microRNAs

Fhit–Fdxr interaction in the mitochondria: modulation of reactive oxygen species generation and apoptosis in cancer cells

Programmed DNA Damage and Physiological DSBs: Mapping, Biological Significance and Perturbations in Disease States

WWOX promotes osteosarcoma development via upregulation of Myc

Twist1-induced miR-199a-3p promotes liver fibrosis by suppressing caveolin-2 and activating TGF-β pathway

MicroRNAs/TP53 feedback circuitry in glioblastoma multiforme

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