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Alarmins: Feel the Stress

The Journal of immunology (1950), 2017-02, Vol.198 (4), p.1395-1402

2017

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Immunotherapeutic approaches of IL‐1 neutralization in the tumor microenvironment

Journal of leukocyte biology, 2017-08, Vol.102 (2), p.293-306

2017

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Blocking IL-1β reverses the immunosuppression in mouse breast cancer and synergizes with anti–PD-1 for tumor abrogation

Proceedings of the National Academy of Sciences - PNAS, 2019-01, Vol.116 (4), p.1361-1369

2019

Volltextzugriff (PDF)

The role IL-1 in tumor-mediated angiogenesis

Frontiers in physiology, 2014-03, Vol.5, p.114-114

2014

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Telmisartan Modulates Glial Activation: In Vitro and In Vivo Studies

PloS one, 2016-05, Vol.11 (5), p.e0155823-e0155823

2016

Volltextzugriff (PDF)

Is interleukin-1 a good or bad 'guy' in tumor immunobiology and immunotherapy

Immunological reviews, 2008-04, Vol.222 (1), p.222-241

2008

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IL-1 in Colon Inflammation, Colon Carcinogenesis and Invasiveness of Colon Cancer

Cancer microenvironment, 2015-12, Vol.8 (3), p.187-200

2015

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Targeting the Tumor Microenvironment by Intervention in Interleukin-1 Biology

Current pharmaceutical design, 2017-01, Vol.23 (32), p.4893

2017

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Interleukin-1 α

Seminars in immunology, 2013-12, Vol.25 (6), p.430-438

2013

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IL-1α is a DNA damage sensor linking genotoxic stress signaling to sterile inflammation and innate immunity

Scientific reports, 2015-10, Vol.5 (1), p.14756-14756, Article 14756

2015

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Interleukin-1β regulates fat-liver crosstalk in obesity by auto-paracrine modulation of adipose tissue inflammation and expandability

PloS one, 2013, Vol.8 (1), p.e53626-e53626

2013

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MABp1 as a novel antibody treatment for advanced colorectal cancer: a randomised, double-blind, placebo-controlled, phase 3 study

The lancet oncology, 2017-02, Vol.18 (2), p.192-201

2017

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IL-1α and IL-1β recruit different myeloid cells and promote different stages of sterile inflammation

The Journal of immunology (1950), 2011-11, Vol.187 (9), p.4835-4843

2011

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Differential release of chromatin-bound IL-1α discriminates between necrotic and apoptotic cell death by the ability to induce sterile inflammation

Proceedings of the National Academy of Sciences - PNAS, 2010-02, Vol.107 (6), p.2574-2579

2010

Volltextzugriff (PDF)

Candesartan ameliorates brain inflammation associated with Alzheimer's disease

CNS neuroscience & therapeutics, 2018-03, Vol.24 (3), p.231-242

2018

Volltextzugriff (PDF)

Non-redundant properties of IL-1α and IL-1β during acute colon inflammation in mice

Gut, 2014-04, Vol.63 (4), p.598-609

2014

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IL‐1β regulates a novel myeloid‐derived suppressor cell subset that impairs NK cell development and function

European journal of immunology, 2010-12, Vol.40 (12), p.3347-3357

2010

Volltextzugriff (PDF)

Interleukin-1α as an intracellular alarmin in cancer biology

Seminars in immunology, 2018-08, Vol.38, p.3-14

2018

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Gene deletion of Interleukin-1α reduces ER stress-induced CHOP expression in macrophages and attenuates the progression of atherosclerosis in apoE-deficient mice

Cytokine (Philadelphia, Pa.), 2023-07, Vol.167, p.156212-156212, Article 156212

2023

Volltextzugriff (PDF)

Lack of interleukin-1α or interleukin-1β inhibits transformation of steatosis to steatohepatitis and liver fibrosis in hypercholesterolemic mice

Journal of hepatology, 2011-11, Vol.55 (5), p.1086-1094

2011

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The role of IL-1β in the early tumor cell-induced angiogenic response

The Journal of immunology (1950), 2013-04, Vol.190 (7), p.3500-3509

2013

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Monocytes-macrophages that express α-smooth muscle actin preserve primitive hematopoietic cells in the bone marrow

Nature immunology, 2012-11, Vol.13 (11), p.1072

2012

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Microglial Activation Is Modulated by Captopril: in Vitro and in Vivo Studies

Frontiers in cellular neuroscience, 2018-05, Vol.12, p.116-116

2018

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Tumor Cell-Associated IL-1α Affects Breast Cancer Progression and Metastasis in Mice through Manipulation of the Tumor Immune Microenvironment

International journal of molecular sciences, 2024-04, Vol.25 (7), p.3950

2024

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The Role of Macrophage-Derived IL-1 in Induction and Maintenance of Angiogenesis

The Journal of immunology (1950), 2009-10, Vol.183 (7), p.4705-4714

2009

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Alarmins: Feel the Stress

Immunotherapeutic approaches of IL‐1 neutralization in the tumor microenvironment

Blocking IL-1β reverses the immunosuppression in mouse breast cancer and synergizes with anti–PD-1 for tumor abrogation

The role IL-1 in tumor-mediated angiogenesis

Telmisartan Modulates Glial Activation: In Vitro and In Vivo Studies

Is interleukin-1 a good or bad 'guy' in tumor immunobiology and immunotherapy

IL-1 in Colon Inflammation, Colon Carcinogenesis and Invasiveness of Colon Cancer

Targeting the Tumor Microenvironment by Intervention in Interleukin-1 Biology

Interleukin-1 α

IL-1α is a DNA damage sensor linking genotoxic stress signaling to sterile inflammation and innate immunity

Interleukin-1β regulates fat-liver crosstalk in obesity by auto-paracrine modulation of adipose tissue inflammation and expandability

MABp1 as a novel antibody treatment for advanced colorectal cancer: a randomised, double-blind, placebo-controlled, phase 3 study

IL-1α and IL-1β recruit different myeloid cells and promote different stages of sterile inflammation

Differential release of chromatin-bound IL-1α discriminates between necrotic and apoptotic cell death by the ability to induce sterile inflammation

Candesartan ameliorates brain inflammation associated with Alzheimer's disease

Non-redundant properties of IL-1α and IL-1β during acute colon inflammation in mice

IL‐1β regulates a novel myeloid‐derived suppressor cell subset that impairs NK cell development and function

Interleukin-1α as an intracellular alarmin in cancer biology

Gene deletion of Interleukin-1α reduces ER stress-induced CHOP expression in macrophages and attenuates the progression of atherosclerosis in apoE-deficient mice

Lack of interleukin-1α or interleukin-1β inhibits transformation of steatosis to steatohepatitis and liver fibrosis in hypercholesterolemic mice

The role of IL-1β in the early tumor cell-induced angiogenic response

Monocytes-macrophages that express α-smooth muscle actin preserve primitive hematopoietic cells in the bone marrow

Microglial Activation Is Modulated by Captopril: in Vitro and in Vivo Studies

Tumor Cell-Associated IL-1α Affects Breast Cancer Progression and Metastasis in Mice through Manipulation of the Tumor Immune Microenvironment

The Role of Macrophage-Derived IL-1 in Induction and Maintenance of Angiogenesis

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