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Thyclotides, tetrahydrofuran-modified peptide nucleic acids that efficiently penetrate cells and inhibit microRNA-21

Nucleic acids research, 2022-10, Vol.50 (19), p.10839-10856

2022

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PNA Clamping in Nucleic Acid Amplification Protocols to Detect Single Nucleotide Mutations Related to Cancer

Molecules (Basel, Switzerland), 2020-02, Vol.25 (4), p.786

2020

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Cyclopentane FIT-PNAs: bright RNA sensors

Chemical communications (Cambridge, England), 2021-01, Vol.57 (4), p.54-543

2021

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Non-natural nucleic acids for synthetic biology

Current opinion in chemical biology, 2009-12, Vol.13 (5), p.687-696

Appella, Daniel H

2009

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Conformational constraints of cyclopentane peptide nucleic acids facilitate tunable binding to DNA

Nucleic acids research, 2021-01, Vol.49 (2), p.713-725

2021

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A trapped human PPM1A–phosphopeptide complex reveals structural features critical for regulation of PPM protein phosphatase activity

The Journal of biological chemistry, 2018-05, Vol.293 (21), p.7993-8008

2018

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γ-Substituted Peptide Nucleic Acids Constructed from L-Lysine are a Versatile Scaffold for Multifunctional Display

Angewandte Chemie (International ed.), 2007-01, Vol.46 (9), p.1414-1418

2007

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Aziridination of Aliphatic Alkenes Catalyzed by N-Heterocyclic Carbene Copper Complexes

Organic letters, 2008-04, Vol.10 (7), p.1497-1500

2008

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Detecting the FLJ22447 lncRNA in Ovarian Cancer with Cyclopentane-Modified FIT-PNAs (cpFIT-PNAs)

Biomolecules (Basel, Switzerland), 2024-05, Vol.14 (6), p.609

2024

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Programmable multivalent display of receptor ligands using peptide nucleic acid nanoscaffolds

Nature communications, 2012-01, Vol.3 (1), p.614-614, Article 614

2012

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Advantages of peptide nucleic acids as diagnostic platforms for detection of nucleic acids in resource-limited settings

The Journal of infectious diseases, 2010-04, Vol.201 (Supplement-1), p.S42-S45

2010

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Click Dimers To Target HIV TAR RNA Conformation

Biochemistry (Easton), 2012-03, Vol.51 (11), p.2331-2347

2012

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Chemical Features Important for Activity in a Class of Inhibitors Targeting the Wip1 Flap Subdomain

ChemMedChem, 2018-05, Vol.13 (9), p.894-901

2018

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Optimization of a Cyclic Peptide Inhibitor of Ser/Thr Phosphatase PPM1D (Wip1)

Biochemistry (Easton), 2011-05, Vol.50 (21), p.4537-4549

2011

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Small-molecule inactivation of HIV-1 NCp7 by repetitive intracellular acyl transfer

Nature chemical biology, 2010-12, Vol.6 (12), p.887-889

2010

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Synthesis of Fmoc-Protected (S,S)-trans-Cyclopentane Diamine Monomers Enables the Preparation and Study of Conformationally Restricted Peptide Nucleic Acids

Organic letters, 2018-12, Vol.20 (23), p.7637-7640

2018

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Correction: Cyclopentane FIT-PNAs: bright RNA sensors

Chemical communications (Cambridge, England), 2023-09, Vol.59 (77), p.11593-11593

2023

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Stabilization of G-quadruplex in the BCL2 promoter region in double-stranded DNA by invading short PNAs

Nucleic acids research, 2009-12, Vol.37 (22), p.7570-7580

2009

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Targeting DNA G-quadruplex structures with peptide nucleic acids

Current pharmaceutical design, 2012-05, Vol.18 (14), p.1984-1991

2012

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Targeting a Dark Excited State of HIV‐1 Nucleocapsid by Antiretroviral Thioesters Revealed by NMR Spectroscopy

Angewandte Chemie International Edition, 2018-03, Vol.57 (10), p.2687-2691

International ed. in English, 2018

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Inhibition of multidrug resistance by SV40 pseudovirion delivery of an antigene peptide nucleic acid (PNA) in cultured cells

PloS one, 2011-03, Vol.6 (3), p.e17981-e17981

2011

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Crystal structure and mechanistic studies of the PPM1D serine/threonine phosphatase catalytic domain

The Journal of biological chemistry, 2024-08, Vol.300 (8), p.107561, Article 107561

2024

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A Biotinylated cpFIT-PNA Platform for the Facile Detection of Drug Resistance to Artemisinin in Plasmodium falciparum

ACS sensors, 2024-03, Vol.9 (3), p.1458-1464

2024

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Reaction Kinetics Direct a Rational Synthesis of an HIV‐1 Inactivator of Nucleocapsid Protein 7 and Provide Mechanistic Insight into Cellular Metabolism and Antiviral Activity

Chemistry : a European journal, 2018-07, Vol.24 (38), p.9485-9489

2018

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G-quadruplex formation between G-rich PNA and homologous sequences in oligonucleotides and supercoiled plasmid DNA

Nucleic acid therapeutics, 2015-04, Vol.25 (2), p.78-84

2015

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Thyclotides, tetrahydrofuran-modified peptide nucleic acids that efficiently penetrate cells and inhibit microRNA-21

PNA Clamping in Nucleic Acid Amplification Protocols to Detect Single Nucleotide Mutations Related to Cancer

Cyclopentane FIT-PNAs: bright RNA sensors

Non-natural nucleic acids for synthetic biology

Conformational constraints of cyclopentane peptide nucleic acids facilitate tunable binding to DNA

A trapped human PPM1A–phosphopeptide complex reveals structural features critical for regulation of PPM protein phosphatase activity

γ-Substituted Peptide Nucleic Acids Constructed from L-Lysine are a Versatile Scaffold for Multifunctional Display

Aziridination of Aliphatic Alkenes Catalyzed by N-Heterocyclic Carbene Copper Complexes

Detecting the FLJ22447 lncRNA in Ovarian Cancer with Cyclopentane-Modified FIT-PNAs (cpFIT-PNAs)

Programmable multivalent display of receptor ligands using peptide nucleic acid nanoscaffolds

Advantages of peptide nucleic acids as diagnostic platforms for detection of nucleic acids in resource-limited settings

Click Dimers To Target HIV TAR RNA Conformation

Chemical Features Important for Activity in a Class of Inhibitors Targeting the Wip1 Flap Subdomain

Optimization of a Cyclic Peptide Inhibitor of Ser/Thr Phosphatase PPM1D (Wip1)

Small-molecule inactivation of HIV-1 NCp7 by repetitive intracellular acyl transfer

Synthesis of Fmoc-Protected (S,S)-trans-Cyclopentane Diamine Monomers Enables the Preparation and Study of Conformationally Restricted Peptide Nucleic Acids

Correction: Cyclopentane FIT-PNAs: bright RNA sensors

Stabilization of G-quadruplex in the BCL2 promoter region in double-stranded DNA by invading short PNAs

Targeting DNA G-quadruplex structures with peptide nucleic acids

Targeting a Dark Excited State of HIV‐1 Nucleocapsid by Antiretroviral Thioesters Revealed by NMR Spectroscopy

Inhibition of multidrug resistance by SV40 pseudovirion delivery of an antigene peptide nucleic acid (PNA) in cultured cells

Crystal structure and mechanistic studies of the PPM1D serine/threonine phosphatase catalytic domain

A Biotinylated cpFIT-PNA Platform for the Facile Detection of Drug Resistance to Artemisinin in Plasmodium falciparum

Reaction Kinetics Direct a Rational Synthesis of an HIV‐1 Inactivator of Nucleocapsid Protein 7 and Provide Mechanistic Insight into Cellular Metabolism and Antiviral Activity

G-quadruplex formation between G-rich PNA and homologous sequences in oligonucleotides and supercoiled plasmid DNA

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