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PrimeDesign software for rapid and simplified design of prime editing guide RNAs

Nature communications, 2021-02, Vol.12 (1), p.1034-6, Article 1034

2021

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Efficient C•G-to-G•C base editors developed using CRISPRi screens, target-library analysis, and machine learning

Nature biotechnology, 2021-11, Vol.39 (11), p.1414-1425

2021

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Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors

Nature biotechnology, 2020-07, Vol.38 (7), p.824-844

2020

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Programmable deletion, replacement, integration and inversion of large DNA sequences with twin prime editing

Nature biotechnology, 2022-05, Vol.40 (5), p.731-740

2022

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Engineered pegRNAs improve prime editing efficiency

Nature biotechnology, 2022-03, Vol.40 (3), p.402-410

2022

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Super-multiplex vibrational imaging

Nature (London), 2017-04, Vol.544 (7651), p.465-470

2017

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Search-and-replace genome editing without double-strand breaks or donor DNA

Nature (London), 2019-12, Vol.576 (7785), p.149-157

2019

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A Common Diaryl Ether Intermediate for the Gram-Scale Synthesis of Oxazine and Xanthene Fluorophores

Angewandte Chemie International Edition, 2013-01, Vol.52 (2), p.650-654

International ed. in English, 2013

Volltextzugriff (PDF)

Prime genome editing in rice and wheat

Nature biotechnology, 2020-05, Vol.38 (5), p.582-585

2020

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Efficient prime editing in mouse brain, liver and heart with dual AAVs

Nature biotechnology, 2024-02, Vol.42 (2), p.253-264

2024

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Interrogation of Eukaryotic Stop Codon Readthrough Signals by in Vitro RNA Selection

Biochemistry (Easton), 2019-02, Vol.58 (8), p.1167-1178

2019

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Synthesis of photoactivatable azido-acyl caged oxazine fluorophores for live-cell imaging

Chemical communications (Cambridge, England), 2016-01, Vol.52 (60), p.9442-9445

2016

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Reprogramming eukaryotic translation with ligand-responsive synthetic RNA switches

Nature methods, 2016-05, Vol.13 (5), p.453-458

2016

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Author Correction: Efficient C•G-to-G•C base editors developed using CRISPRi screens, target-library analysis, and machine learning

Nature biotechnology, 2023-11, Vol.41 (11), p.1655-1655

2023

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Author Correction: Engineered pegRNAs improve prime editing efficiency

Nature biotechnology, 2022-03, Vol.40 (3), p.432-432

2022

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Synthetic Studies toward 3-(Acylamino)-1H-indazoles and Development of a One-Pot, Microwave-Assisted, Oxadiazole Condensation/Boulton-Katritzky Rearrangement

Synlett, 2011-12, Vol.2011 (20), p.3018-3022

2011

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A Common Diaryl Ether Intermediate for the Gram‐Scale Synthesis of Oxazine and Xanthene Fluorophores

Angewandte Chemie, 2013-01, Vol.125 (2), p.678-682

2013

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Novel 2,3,4,5-tetrahydro-benzo[d]azepine derivatives of 2,4-diaminopyrimidine, selective and orally bioavailable ALK inhibitors with antitumor efficacy in ALCL mouse models

Bioorganic & medicinal chemistry letters, 2011-01, Vol.21 (1), p.463-466

2011

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Discovery of a Potent Inhibitor of Anaplastic Lymphoma Kinase with in Vivo Antitumor Activity

ACS medicinal chemistry letters, 2010-12, Vol.1 (9), p.493-498

2010

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Efficient CG-to-GC base editors developed using CRISPRi screens, target-library analysis, and machine learning

Nature biotechnology, 2021-11, Vol.39 (11), p.1414

2021

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Prime Editing Efficiently and Precisely Corrects Causative Mutation in Chronic Granulomatous Disease, Restoring Myeloid Function: Toward Development of a Prime Edited Autologous Hematopoietic Stem Cell Therapy

Blood, 2023-11, Vol.142 (Supplement 1), p.7129-7129

2023

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Multiplex Prime Editing and PASSIGE TM for Non-Viral Generation of an Allogeneic CAR-T Cell Product

Blood, 2023-11, Vol.142 (Supplement 1), p.4803-4803

2023

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Synthesis of photoactivatable azido-acyl caged oxazine fluorophores for live-cell imagingElectronic supplementary information (ESI) available. See DOI: 10.1039/c6cc04882j

2016-07

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Development of a set of C•G-to-G•C transversion base editors from CRISPRi screens, target-library analysis, and machine learning

Nature biotechnology, 2021-06, Vol.39 (11), p.1414-1425

2021

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PrimeDesign software for rapid and simplified design of prime editing guide RNAs

Efficient C•G-to-G•C base editors developed using CRISPRi screens, target-library analysis, and machine learning

Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors

Programmable deletion, replacement, integration and inversion of large DNA sequences with twin prime editing

Engineered pegRNAs improve prime editing efficiency

Super-multiplex vibrational imaging

Search-and-replace genome editing without double-strand breaks or donor DNA

A Common Diaryl Ether Intermediate for the Gram-Scale Synthesis of Oxazine and Xanthene Fluorophores

Prime genome editing in rice and wheat

Efficient prime editing in mouse brain, liver and heart with dual AAVs

Interrogation of Eukaryotic Stop Codon Readthrough Signals by in Vitro RNA Selection

A prime editor mouse to model a broad spectrum of somatic mutations in vivo

Synthesis of photoactivatable azido-acyl caged oxazine fluorophores for live-cell imaging

Reprogramming eukaryotic translation with ligand-responsive synthetic RNA switches

Author Correction: Efficient C•G-to-G•C base editors developed using CRISPRi screens, target-library analysis, and machine learning

Author Correction: Engineered pegRNAs improve prime editing efficiency

Synthetic Studies toward 3-(Acylamino)-1H-indazoles and Development of a One-Pot, Microwave-Assisted, Oxadiazole Condensation/Boulton-Katritzky Rearrangement

A Common Diaryl Ether Intermediate for the Gram‐Scale Synthesis of Oxazine and Xanthene Fluorophores

Novel 2,3,4,5-tetrahydro-benzo[d]azepine derivatives of 2,4-diaminopyrimidine, selective and orally bioavailable ALK inhibitors with antitumor efficacy in ALCL mouse models

Discovery of a Potent Inhibitor of Anaplastic Lymphoma Kinase with in Vivo Antitumor Activity

Efficient CG-to-GC base editors developed using CRISPRi screens, target-library analysis, and machine learning

Prime Editing Efficiently and Precisely Corrects Causative Mutation in Chronic Granulomatous Disease, Restoring Myeloid Function: Toward Development of a Prime Edited Autologous Hematopoietic Stem Cell Therapy

Multiplex Prime Editing and PASSIGE TM for Non-Viral Generation of an Allogeneic CAR-T Cell Product

Synthesis of photoactivatable azido-acyl caged oxazine fluorophores for live-cell imagingElectronic supplementary information (ESI) available. See DOI: 10.1039/c6cc04882j

Development of a set of C•G-to-G•C transversion base editors from CRISPRi screens, target-library analysis, and machine learning

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