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Comprehensive microRNA profiling in acetaminophen toxicity identifies novel circulating biomarkers for human liver and kidney injury

Scientific reports, 2015-10, Vol.5 (1), p.15501, Article 15501

2015

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The Effects of Heparins on the Liver: Application of Mechanistic Serum Biomarkers in a Randomized Study in Healthy Volunteers

Clinical pharmacology and therapeutics, 2012-08, Vol.92 (2), p.214-220

2012

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The functions of HMGB1 depend on molecular localization and post-translational modifications

Journal of internal medicine, 2014-11, Vol.276 (5), p.420-424

2014

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Circulating acetaminophen metabolites are toxicokinetic biomarkers of acute liver injury

Clinical pharmacology and therapeutics, 2017-04, Vol.101 (4), p.531-540

2017

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Serum microRNA Biomarkers for Drug-Induced Liver Injury

Clinical pharmacology and therapeutics, 2012-09, Vol.92 (3), p.291-293

2012

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Role of reactive metabolites in drug-induced hepatotoxicity

Handbook of experimental pharmacology, 2010 (196), p.165

2010

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The haptoglobin beta subunit sequesters HMGB1 toxicity in sterile and infectious inflammation

Journal of internal medicine, 2017-07, Vol.282 (1), p.76-93

2017

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Refining Liver Safety Risk Assessment: Application of Mechanistic Modeling and Serum Biomarkers to Cimaglermin Alfa (GGF2) Clinical Trials

Clinical pharmacology and therapeutics, 2017-12, Vol.102 (6), p.961-969

2017

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HMGB1 mediates splenomegaly and expansion of splenic CD11b+ Ly-6C(high) inflammatory monocytes in murine sepsis survivors

Journal of internal medicine, 2013-10, Vol.274 (4), p.381-390

2013

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Expression of Concern: The haptoglobin beta subunit sequesters HMGB1 toxicity in sterile and infectious inflammation

Journal of internal medicine, 2017-07, Vol.282 (1), p.76-93

2017

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Expression of Concern: The functions of HMGB1 depend on molecular localization and post‐translational modifications

Journal of internal medicine, 2014-11, Vol.276 (5), p.420-424

2014

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Optimising the use of medicines to reduce acute kidney injury in children and babies

Pharmacology & therapeutics (Oxford), 2017-06, Vol.174, p.55-62

2017

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Drug bioactivation and protein adduct formation in the pathogenesis of drug-induced toxicity

Chemico-biological interactions, 2011-06, Vol.192 (1), p.30-36

2011

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Mechanism-based bioanalysis and biomarkers for hepatic chemical stress

Xenobiotica, 2009-08, Vol.39 (8), p.565-577

2009

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Expression of Concern: HMGB1 mediates splenomegaly and expansion of splenic CD11b+ Ly‐6Chigh inflammatory monocytes in murine sepsis survivors

Journal of internal medicine, 2013-10, Vol.274 (4), p.381-390

2013

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The many faces of HMGB1: molecular structure-functional activity in inflammation, apoptosis, and chemotaxis

Journal of leukocyte biology, 2013-06, Vol.93 (6), p.865-873

2013

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JAK/STAT1 signaling promotes HMGB1 hyperacetylation and nuclear translocation

Proceedings of the National Academy of Sciences - PNAS, 2014-02, Vol.111 (8), p.3068-3073

2014

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MD-2 is required for disulfide HMGB1-dependent TLR4 signaling

The Journal of experimental medicine, 2015-01, Vol.212 (1), p.5-14

2015

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Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release

The Journal of experimental medicine, 2012-08, Vol.209 (9), p.1519-1528

2012

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Novel role of PKR in inflammasome activation and HMGB1 release

Nature (London), 2012-08, Vol.488 (7413), p.670-674

2012

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A novel high mobility group box 1 neutralizing chimeric antibody attenuates drug‐induced liver injury and postinjury inflammation in mice

Hepatology (Baltimore, Md.), 2016-11, Vol.64 (5), p.1699-1710

2016

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Brain-released alarmins and stress response synergize in accelerating atherosclerosis progression after stroke

Science translational medicine, 2018-03, Vol.10 (432)

2018

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Molecular forms of HMGB1 and keratin-18 as mechanistic biomarkers for mode of cell death and prognosis during clinical acetaminophen hepatotoxicity

Journal of hepatology, 2012-01, Vol.56 (5), p.1070-1079

2012

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Are some people at increased risk of paracetamol-induced liver injury? A critical review of the literature

European journal of clinical pharmacology, 2018-02, Vol.74 (2), p.147-160

2018

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Die Qualität von Bürgerbeteiligungsverfahren: Evaluation und Sicherung von Standards am Beispiel von Planungszellen und Bürgergutachten

1, 2014

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Comprehensive microRNA profiling in acetaminophen toxicity identifies novel circulating biomarkers for human liver and kidney injury

The Effects of Heparins on the Liver: Application of Mechanistic Serum Biomarkers in a Randomized Study in Healthy Volunteers

The functions of HMGB1 depend on molecular localization and post-translational modifications

Circulating acetaminophen metabolites are toxicokinetic biomarkers of acute liver injury

Serum microRNA Biomarkers for Drug-Induced Liver Injury

Role of reactive metabolites in drug-induced hepatotoxicity

The haptoglobin beta subunit sequesters HMGB1 toxicity in sterile and infectious inflammation

Refining Liver Safety Risk Assessment: Application of Mechanistic Modeling and Serum Biomarkers to Cimaglermin Alfa (GGF2) Clinical Trials

HMGB1 mediates splenomegaly and expansion of splenic CD11b+ Ly-6C(high) inflammatory monocytes in murine sepsis survivors

Expression of Concern: The haptoglobin beta subunit sequesters HMGB1 toxicity in sterile and infectious inflammation

Expression of Concern: The functions of HMGB1 depend on molecular localization and post‐translational modifications

Optimising the use of medicines to reduce acute kidney injury in children and babies

Drug bioactivation and protein adduct formation in the pathogenesis of drug-induced toxicity

Mechanism-based bioanalysis and biomarkers for hepatic chemical stress

Expression of Concern: HMGB1 mediates splenomegaly and expansion of splenic CD11b+ Ly‐6Chigh inflammatory monocytes in murine sepsis survivors

The many faces of HMGB1: molecular structure-functional activity in inflammation, apoptosis, and chemotaxis

JAK/STAT1 signaling promotes HMGB1 hyperacetylation and nuclear translocation

MD-2 is required for disulfide HMGB1-dependent TLR4 signaling

Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release

Novel role of PKR in inflammasome activation and HMGB1 release

A novel high mobility group box 1 neutralizing chimeric antibody attenuates drug‐induced liver injury and postinjury inflammation in mice

Brain-released alarmins and stress response synergize in accelerating atherosclerosis progression after stroke

Molecular forms of HMGB1 and keratin-18 as mechanistic biomarkers for mode of cell death and prognosis during clinical acetaminophen hepatotoxicity

Are some people at increased risk of paracetamol-induced liver injury? A critical review of the literature

Die Qualität von Bürgerbeteiligungsverfahren: Evaluation und Sicherung von Standards am Beispiel von Planungszellen und Bürgergutachten

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