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Mitochondria in Health and Disease

Cells (Basel, Switzerland), 2019-07, Vol.8 (7), p.680

2019

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Dysregulated Provision of Oxidisable Substrates to the Mitochondria in ME/CFS Lymphoblasts

International journal of molecular sciences, 2021-02, Vol.22 (4), p.2046

2021

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Relationships between Mitochondrial Function, AMPK, and TORC1 Signaling in Lymphoblasts with Premutation Alleles of the FMR1 Gene

International journal of molecular sciences, 2021-09, Vol.22 (19), p.10393

2021

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Misfolded α-synuclein causes hyperactive respiration without functional deficit in live neuroblastoma cells

Disease models & mechanisms, 2020-01, Vol.13 (1)

2020

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Interactions and Cytotoxicity of Human Neurodegeneration- Associated Proteins Tau and α-Synuclein in the Simple Model Dictyostelium discoideum

Frontiers in cell and developmental biology, 2021-09, Vol.9, p.741662-741662

2021

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The Parkinson’s Disease-Associated Protein DJ-1 Protects Dictyostelium Cells from AMPK-Dependent Outcomes of Oxidative Stress

Cells (Basel, Switzerland), 2021-07, Vol.10 (8), p.1874

2021

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Mitochondrial HTRA2 Plays a Positive, Protective Role in Dictyostelium discoideum but Is Cytotoxic When Overexpressed

Genes, 2018-07, Vol.9 (7), p.355

2018

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Immortalized Parkinson's disease lymphocytes have enhanced mitochondrial respiratory activity

Disease models & mechanisms, 2016-11, Vol.9 (11), p.1295-1305

2016

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The Parkinson's disease-associated protein DJ-1 plays a positive nonmitochondrial role in endocytosis in Dictyostelium cells

Disease models & mechanisms, 2017-10, Vol.10 (10), p.1261-1271

2017

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Science around the world

Trends in molecular medicine, 2024-05, Vol.30 (5), p.417-419

2024

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Cellular Bioenergetics and AMPK and TORC1 Signalling in Blood Lymphoblasts Are Biomarkers of Clinical Status in FMR1 Premutation Carriers

Frontiers in psychiatry, 2021-11, Vol.12, p.747268-747268

2021

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Modelling of Neuronal Ceroid Lipofuscinosis Type 2 in Dictyostelium discoideum Suggests That Cytopathological Outcomes Result from Altered TOR Signalling

Cells (Basel, Switzerland), 2019-05, Vol.8 (5), p.469

2019

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A Conserved Role for LRRK2 and Roco Proteins in the Regulation of Mitochondrial Activity

Frontiers in cell and developmental biology, 2021-09, Vol.9, p.734554-734554

2021

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Cytotoxicity and Mitochondrial Dysregulation Caused by α-Synuclein in Dictyostelium discoideum

Cells (Basel, Switzerland), 2020-10, Vol.9 (10), p.2289

2020

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Unravelling shared mechanisms: insights from recent ME/CFS research to illuminate long COVID pathologies

Trends in molecular medicine, 2024-05, Vol.30 (5), p.443-458

2024

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The Spectrum of Neurological and White Matter Changes and Premutation Status Categories of Older Male Carriers of the FMR1 Alleles Are Linked to Genetic (CGG and FMR1 mRNA) and Cellular Stress (AMPK) Markers

Frontiers in genetics, 2018-11, Vol.9, p.531-531

2018

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Dictyostelium discoideum nucleoside diphosphate kinase C plays a negative regulatory role in phagocytosis, macropinocytosis and exocytosis

PloS one, 2011-10, Vol.6 (10), p.e26024

2011

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Could the kynurenine pathway be the key missing piece of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) complex puzzle?

Cellular and molecular life sciences : CMLS, 2022-08, Vol.79 (8), p.412-412, Article 412

2022

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Diverse cytopathologies in mitochondrial disease are caused by AMP-activated protein kinase signaling

Molecular biology of the cell, 2007-05, Vol.18 (5), p.1874-1886

2007

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Dysregulation of the Kynurenine Pathway, Cytokine Expression Pattern, and Proteomics Profile Link to Symptomology in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)

Molecular neurobiology, 2024-07, Vol.61 (7), p.3771-3787

2024

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The LRRK2-related Roco kinase Roco2 is regulated by Rab1A and controls the actin cytoskeleton

Molecular biology of the cell, 2011-07, Vol.22 (13), p.2198-2211

2011

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Dictyostelium discoideum--a model for many reasons

Molecular and cellular biochemistry, 2009-09, Vol.329 (1-2), p.73-91

2009

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A Dictyostelium discoideum mitochondrial fluorescent tagging vector that does not affect respiratory function

Biochemistry and biophysics reports, 2020-07, Vol.22, p.100751-100751, Article 100751

2020

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The Dictyostelium model for mitochondrial biology and disease

The International journal of developmental biology, 2019, Vol.63 (8-9-10), p.497-508

2019

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Mitochondrial Stress Tests Using Seahorse Respirometry on Intact Dictyostelium discoideum Cells

Methods in molecular biology (Clifton, N.J.), 2016-01, Vol.1407, p.41

2016

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Mitochondria in Health and Disease

Dysregulated Provision of Oxidisable Substrates to the Mitochondria in ME/CFS Lymphoblasts

Relationships between Mitochondrial Function, AMPK, and TORC1 Signaling in Lymphoblasts with Premutation Alleles of the FMR1 Gene

Misfolded α-synuclein causes hyperactive respiration without functional deficit in live neuroblastoma cells

Interactions and Cytotoxicity of Human Neurodegeneration- Associated Proteins Tau and α-Synuclein in the Simple Model Dictyostelium discoideum

The Parkinson’s Disease-Associated Protein DJ-1 Protects Dictyostelium Cells from AMPK-Dependent Outcomes of Oxidative Stress

Mitochondrial HTRA2 Plays a Positive, Protective Role in Dictyostelium discoideum but Is Cytotoxic When Overexpressed

Immortalized Parkinson's disease lymphocytes have enhanced mitochondrial respiratory activity

The Parkinson's disease-associated protein DJ-1 plays a positive nonmitochondrial role in endocytosis in Dictyostelium cells

Science around the world

Cellular Bioenergetics and AMPK and TORC1 Signalling in Blood Lymphoblasts Are Biomarkers of Clinical Status in FMR1 Premutation Carriers

Modelling of Neuronal Ceroid Lipofuscinosis Type 2 in Dictyostelium discoideum Suggests That Cytopathological Outcomes Result from Altered TOR Signalling

A Conserved Role for LRRK2 and Roco Proteins in the Regulation of Mitochondrial Activity

Cytotoxicity and Mitochondrial Dysregulation Caused by α-Synuclein in Dictyostelium discoideum

Unravelling shared mechanisms: insights from recent ME/CFS research to illuminate long COVID pathologies

The Spectrum of Neurological and White Matter Changes and Premutation Status Categories of Older Male Carriers of the FMR1 Alleles Are Linked to Genetic (CGG and FMR1 mRNA) and Cellular Stress (AMPK) Markers

Dictyostelium discoideum nucleoside diphosphate kinase C plays a negative regulatory role in phagocytosis, macropinocytosis and exocytosis

Could the kynurenine pathway be the key missing piece of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) complex puzzle?

Diverse cytopathologies in mitochondrial disease are caused by AMP-activated protein kinase signaling

Dysregulation of the Kynurenine Pathway, Cytokine Expression Pattern, and Proteomics Profile Link to Symptomology in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)

The LRRK2-related Roco kinase Roco2 is regulated by Rab1A and controls the actin cytoskeleton

Dictyostelium discoideum--a model for many reasons

A Dictyostelium discoideum mitochondrial fluorescent tagging vector that does not affect respiratory function

The Dictyostelium model for mitochondrial biology and disease

Mitochondrial Stress Tests Using Seahorse Respirometry on Intact Dictyostelium discoideum Cells

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