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Modulation of the endoplasmic reticulum–mitochondria interface in Alzheimer’s disease and related models

Proceedings of the National Academy of Sciences - PNAS, 2013-05, Vol.110 (19), p.7916-7921

2013

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Amyloid-β accumulation in human astrocytes induces mitochondrial disruption and changed energy metabolism

Journal of neuroinflammation, 2023-02, Vol.20 (1), p.43-43, Article 43

2023

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amyloid β-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae

Proceedings of the National Academy of Sciences - PNAS, 2008-09, Vol.105 (35), p.13145-13150

2008

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MIEF1/2 orchestrate mitochondrial dynamics through direct engagement with both the fission and fusion machineries

BMC biology, 2021-10, Vol.19 (1), p.229-229, Article 229

2021

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Strategic role for mitochondria in Alzheimer's disease and cancer

Antioxidants & redox signaling, 2012-06, Vol.16 (12), p.1476

2012

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Mitochondria-Endoplasmic Reticulum Interplay Regulates Exo-Cytosis in Human Neuroblastoma Cells

Cells (Basel, Switzerland), 2022-02, Vol.11 (3), p.514

2022

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Reduction of PINK1 or DJ‐1 impair mitochondrial motility in neurites and alter ER‐mitochondria contacts

Journal of cellular and molecular medicine, 2018-11, Vol.22 (11), p.5439-5449

2018

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The Potential of Small Molecules to Modulate the Mitochondria–Endoplasmic Reticulum Interplay in Alzheimer’s Disease

Frontiers in cell and developmental biology, 2022-08, Vol.10, p.920228-920228

2022

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Amyloid Β-Peptide Increases Mitochondria-Endoplasmic Reticulum Contact Altering Mitochondrial Function and Autophagosome Formation in Alzheimer's Disease-Related Models

Cells (Basel, Switzerland), 2020-11, Vol.9 (12), p.2552

2020

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Mechanism of Peptide Binding and Cleavage by the Human Mitochondrial Peptidase Neurolysin

Journal of molecular biology, 2018-02, Vol.430 (3), p.348-362

2018

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Center for Alzheimer Research at Karolinska Institutet, Sweden

Alzheimer's & dementia, 2023-12, Vol.19 (S23), p.n/a

2023

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The Molecular Assembly State of Drp1 Controls its Association With the Mitochondrial Recruitment Receptors Mff and MIEF1/2

Frontiers in cell and developmental biology, 2021-11, Vol.9, p.706687-706687

2021

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Beyond the critical point: An overview of excitotoxicity, calcium overload and the downstream consequences

Neuroscience letters, 2018-01, Vol.663, p.79-85

2018

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Alterations in mitochondria-endoplasmic reticulum connectivity in human brain biopsies from idiopathic normal pressure hydrocephalus patients

Acta neuropathologica communications, 2018-10, Vol.6 (1), p.102-102, Article 102

2018

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Amyloid-β peptides are generated in mitochondria-associated endoplasmic reticulum membranes

Journal of Alzheimer's disease, 2015-01, Vol.43 (2), p.369

2015

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Biomarkers for apoptosis in Alzheimer's disease

International journal of geriatric psychiatry, 2005-02, Vol.20 (2), p.101-105

2005

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Presenilin-1 is located in rat mitochondria

Biochemical and biophysical research communications, 2002-07, Vol.295 (3), p.766-770

2002

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p53 expression in nitric oxide-induced apoptosis

FEBS letters, 1994-11, Vol.355 (1), p.23-26

1994

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Calcineurin and mitochondrial function in glutamate-induced neuronal cell death

FEBS letters, 1996-10, Vol.394 (3), p.321-324

1996

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TOM70 Sustains Cell Bioenergetics by Promoting IP3R3-Mediated ER to Mitochondria Ca2+ Transfer

Current biology, 2018-02, Vol.28 (3), p.369-382.e6

2018

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Isolation of Mitochondria-Associated Membranes (MAM) from Mouse Brain Tissue

Methods in molecular biology (Clifton, N.J.), 2017-01, Vol.1567, p.53

2017

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Mitochondrial hypermetabolism precedes impaired autophagy and synaptic disorganization in App knock-in Alzheimer mouse models

Molecular psychiatry, 2023-09, Vol.28 (9), p.3966-3981

2023

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Amyloid-[beta] accumulation in human astrocytes induces mitochondrial disruption and changed energy metabolism

Journal of neuroinflammation, 2023-02, Vol.20 (1)

2023

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The Sigma-1 Receptor Mediates Pridopidine Rescue of Mitochondrial Function in Huntington Disease Models

Neurotherapeutics, 2021-04, Vol.18 (2), p.1017-1038

2021

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Modulation of the endoplasmic reticulum–mitochondria interface in Alzheimer’s disease and related models

Amyloid-β accumulation in human astrocytes induces mitochondrial disruption and changed energy metabolism

amyloid β-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae

MIEF1/2 orchestrate mitochondrial dynamics through direct engagement with both the fission and fusion machineries

Strategic role for mitochondria in Alzheimer's disease and cancer

Mitochondria-Endoplasmic Reticulum Interplay Regulates Exo-Cytosis in Human Neuroblastoma Cells

Reduction of PINK1 or DJ‐1 impair mitochondrial motility in neurites and alter ER‐mitochondria contacts

The Potential of Small Molecules to Modulate the Mitochondria–Endoplasmic Reticulum Interplay in Alzheimer’s Disease

Amyloid Β-Peptide Increases Mitochondria-Endoplasmic Reticulum Contact Altering Mitochondrial Function and Autophagosome Formation in Alzheimer's Disease-Related Models

Mechanism of Peptide Binding and Cleavage by the Human Mitochondrial Peptidase Neurolysin

Neuronal cell-based high-throughput screen for enhancers of mitochondrial function reveals luteolin as a modulator of mitochondria-endoplasmic reticulum coupling

Center for Alzheimer Research at Karolinska Institutet, Sweden

The Molecular Assembly State of Drp1 Controls its Association With the Mitochondrial Recruitment Receptors Mff and MIEF1/2

Beyond the critical point: An overview of excitotoxicity, calcium overload and the downstream consequences

Alterations in mitochondria-endoplasmic reticulum connectivity in human brain biopsies from idiopathic normal pressure hydrocephalus patients

Amyloid-β peptides are generated in mitochondria-associated endoplasmic reticulum membranes

Biomarkers for apoptosis in Alzheimer's disease

Presenilin-1 is located in rat mitochondria

p53 expression in nitric oxide-induced apoptosis

Calcineurin and mitochondrial function in glutamate-induced neuronal cell death

TOM70 Sustains Cell Bioenergetics by Promoting IP3R3-Mediated ER to Mitochondria Ca2+ Transfer

Isolation of Mitochondria-Associated Membranes (MAM) from Mouse Brain Tissue

Mitochondrial hypermetabolism precedes impaired autophagy and synaptic disorganization in App knock-in Alzheimer mouse models

Amyloid-[beta] accumulation in human astrocytes induces mitochondrial disruption and changed energy metabolism

The Sigma-1 Receptor Mediates Pridopidine Rescue of Mitochondrial Function in Huntington Disease Models

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