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A screen against Leishmania intracellular amastigotes: comparison to a promastigote screen and identification of a host cell-specific hit

PLoS neglected tropical diseases, 2011-07, Vol.5 (7), p.e1253

2011

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Image-Based High-Throughput Drug Screening Targeting the Intracellular Stage of Trypanosoma cruzi, the Agent of Chagas' Disease

Antimicrobial Agents and Chemotherapy, 2010-08, Vol.54 (8), p.3326-3334

2010

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Divergent Modes of Enzyme Inhibition in a Homologous Structure−Activity Series

Journal of medicinal chemistry, 2009-08, Vol.52 (16), p.5005-5008

2009

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Identification of Plasmodium dipeptidyl aminopeptidase allosteric inhibitors by high throughput screening

PloS one, 2019-12, Vol.14 (12), p.e0226270

2019

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Novel non-peptidic vinylsulfones targeting the S2 and S3 subsites of parasite cysteine proteases

Bioorganic & medicinal chemistry letters, 2009-11, Vol.19 (21), p.6218-6221

2009

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Diverse inhibitor chemotypes targeting Trypanosoma cruzi CYP51

PLoS neglected tropical diseases, 2012-07, Vol.6 (7), p.e1736-e1736

2012

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Trypanosoma cruzi CYP51 inhibitor derived from a Mycobacterium tuberculosis screen hit

PLoS neglected tropical diseases, 2009, Vol.3 (2), p.e372

2009

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Mining a cathepsin inhibitor library for new antiparasitic drug leads

PLoS neglected tropical diseases, 2011-05, Vol.5 (5), p.e1023-e1023

2011

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An image-based assay for high throughput screening of Giardia lamblia

Journal of microbiological methods, 2011-03, Vol.84 (3), p.398-405

2011

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In Vivo Antimalarial Activity of the Beta-Carboline Alkaloid Manzamine A

Antimicrobial Agents and Chemotherapy, 2000-06, Vol.44 (6), p.1645-1649

2000

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New Antiinfective and Human 5-HT2 Receptor Binding Natural and Semisynthetic Compounds from the Jamaican Sponge Smenospongia aurea

Journal of natural products (Washington, D.C.), 2002-04, Vol.65 (4), p.476-480

2002

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Small-Molecule Screening for Genetic Diseases

Annual review of genomics and human genetics, 2018-08, Vol.19 (1), p.263-288

2018

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Venetoclax and dinaciclib elicit synergistic preclinical efficacy against hypodiploid acute lymphoblastic leukemia

Haematologica (Roma), 2023-05, Vol.108 (5), p.1272-1283

2023

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Chemical-biological characterization of a cruzain inhibitor reveals a second target and a mammalian off-target

Beilstein journal of organic chemistry, 2013-01, Vol.9 (1), p.15-25

2013

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Pharmacological brake-release of mRNA translation enhances cognitive memory

eLife, 2013-05, Vol.2, p.e00498-e00498

2013

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A gene-expression screen identifies a non-toxic sumoylation inhibitor that mimics SUMO-less human LRH-1 in liver

eLife, 2015-12, Vol.4

2015

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UCSF Small Molecule Discovery Center: innovation, collaboration and chemical biology in the Bay Area

Combinatorial chemistry & high throughput screening, 2014-05, Vol.17 (4), p.333

2014

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Multiparametric High‐Content Assays to Measure Cell Health and Oxidative Damage as a Model for Drug‐Induced Liver Injury

Current protocols in chemical biology, 2020-12, Vol.12 (4), p.e90-n/a

2020

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A benzopyrroloisoquinoline alkaloid from Ficus fistulosa

Phytochemistry letters, 2009-04, Vol.2 (2), p.88-90

2009

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New Antiinfective and Human 5-HT2 Receptor Binding Natural and Semisynthetic Compounds from the Jamaican Sponge Smenospongia a urea

Journal of natural products (Washington, D.C.), 2002-04, Vol.65 (4), p.476-480

2002

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Image-Based High-Throughput Drug Screening Targeting the Intracellular Stage of Tiypanosoma cruzi, the Agent of Chagas' Disease

Antimicrobial agents and chemotherapy, 2010, Vol.54 (8), p.3326-3334

2010

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Immune-mediated parasite clearance in mice infected with Plasmodium berghei foliowing treatment with manzamine A

Parasitology research (1987), 2001, Vol.87 (9), p.715-721

2001

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Isopod mouthpart traits respond to a tropical forest recovery gradient

Oecologia, 2024, Vol.204 (1), p.147-159

2024

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A screen against Leishmania intracellular amastigotes: comparison to a promastigote screen and identification of a host cell-specific hit

Image-Based High-Throughput Drug Screening Targeting the Intracellular Stage of Trypanosoma cruzi, the Agent of Chagas' Disease

Fibrin-targeting immunotherapy protects against neuroinflammation and neurodegeneration

Divergent Modes of Enzyme Inhibition in a Homologous Structure−Activity Series

Identification of Plasmodium dipeptidyl aminopeptidase allosteric inhibitors by high throughput screening

Novel non-peptidic vinylsulfones targeting the S2 and S3 subsites of parasite cysteine proteases

Diverse inhibitor chemotypes targeting Trypanosoma cruzi CYP51

Trypanosoma cruzi CYP51 inhibitor derived from a Mycobacterium tuberculosis screen hit

Mining a cathepsin inhibitor library for new antiparasitic drug leads

An image-based assay for high throughput screening of Giardia lamblia

In Vivo Antimalarial Activity of the Beta-Carboline Alkaloid Manzamine A

New Antiinfective and Human 5-HT2 Receptor Binding Natural and Semisynthetic Compounds from the Jamaican Sponge Smenospongia aurea

Small-Molecule Screening for Genetic Diseases

Venetoclax and dinaciclib elicit synergistic preclinical efficacy against hypodiploid acute lymphoblastic leukemia

Chemical-biological characterization of a cruzain inhibitor reveals a second target and a mammalian off-target

Pharmacological brake-release of mRNA translation enhances cognitive memory

A gene-expression screen identifies a non-toxic sumoylation inhibitor that mimics SUMO-less human LRH-1 in liver

UCSF Small Molecule Discovery Center: innovation, collaboration and chemical biology in the Bay Area

Multiparametric High‐Content Assays to Measure Cell Health and Oxidative Damage as a Model for Drug‐Induced Liver Injury

A benzopyrroloisoquinoline alkaloid from Ficus fistulosa

New Antiinfective and Human 5-HT2 Receptor Binding Natural and Semisynthetic Compounds from the Jamaican Sponge Smenospongia a urea

Guidelines for DNA recombination and repair studies: Mechanistic assays of DNA repair processes

Image-Based High-Throughput Drug Screening Targeting the Intracellular Stage of Tiypanosoma cruzi, the Agent of Chagas' Disease

Immune-mediated parasite clearance in mice infected with Plasmodium berghei foliowing treatment with manzamine A

Isopod mouthpart traits respond to a tropical forest recovery gradient

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