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Future technology insight: mass spectrometry imaging as a tool in drug research and development

British journal of pharmacology, 2015-07, Vol.172 (13), p.3266-3283

2015

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Naloxone reduces levodopa-induced dyskinesias and apomorphine-induced rotations in primate models of parkinsonism

Journal of Neural Transmission, 2002-10, Vol.109 (10), p.1295-1307

2002

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On-Tissue Chemical Derivatization for Comprehensive Mapping of Brain Carboxyl and Aldehyde Metabolites by MALDI–MS Imaging

Journal of the American Society for Mass Spectrometry, 2023-05, Vol.34 (5), p.836-846

2023

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Determination of extracellular release of neurotensin in discrete rat brain regions utilizing in vivo microdialysis/electrospray mass spectrometry

Brain research, 1999-10, Vol.845 (2), p.123-129

1999

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Neuropeptidomics: expanding proteomics downwards

Biochemical Society transactions, 2007-06, Vol.35 (Pt 3), p.588

2007

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l-DOPA produces strong induction of c-fos messenger RNA in dopamine-denervated cortical and striatal areas of the common marmoset

Neuroscience, 2000, Vol.99 (3), p.457-468

2000

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Combining solid-phase preconcentration, capillary electrophoresis and off-line matrix-assisted laser desorption/ionization mass spectrometry: intracerebral metabolic processing of peptide E in vivo

Journal of mass spectrometry., 1999-04, Vol.34 (4), p.377-383

1999

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Direct Targeted Quantitative Molecular Imaging of Neurotransmitters in Brain Tissue Sections

Neuron (Cambridge, Mass.), 2014-11, Vol.84 (4), p.697-707

2014

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Repeated l-DOPA treatment increases c-fos and BDNF mRNAs in the subthalamic nucleus in the 6-OHDA rat model of Parkinson's disease

Brain research, 2006-06, Vol.1095 (1), p.207-210

2006

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Specific molecular mass detection of endogenously released neuropeptides using in vivo microdialysis/mass spectrometry

Journal of neuroscience methods, 1995-11, Vol.62 (1), p.141-147

1995

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Neuropeptidomics: MS Applied to the Discovery of Novel Peptides from the Brain

Analytical chemistry (Washington), 2007-01, Vol.79 (1), p.14-21

2007

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Comprehensive mapping of neurotransmitter networks by MALDI-MS imaging

Nature methods, 2019-10, Vol.16 (10), p.1021

2019

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An animal model for coexisting tardive dyskinesia and tardive Parkinsonism : a glutamate hypothesis for tardive dyskinesia

Clinical neuropharmacology, 1993-02, Vol.16 (1), p.90-95

1993

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Mass Spectrometry Imaging, an Emerging Technology in Neuropsychopharmacology

Neuropsychopharmacology (New York, N.Y.), 2014-01, Vol.39 (1), p.34-49

2014

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Pyrylium Salts as Reactive Matrices for MALDI-MS Imaging of Biologically Active Primary Amines

Journal of the American Society for Mass Spectrometry, 2015-06, Vol.26 (6), p.934-939

2015

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Spatial visualization of comprehensive brain neurotransmitter systems and neuroactive substances by selective in situ chemical derivatization mass spectrometry imaging

Nature protocols, 2021-07, Vol.16 (7), p.3298-3321

2021

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(−)-OSU 6162 inhibits levodopa-induced dyskinesias in a monkey model of Parkinsonʼs disease

Neuroreport, 1997-07, Vol.8 (11), p.2567-2570

1997

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Spatial multimodal analysis of transcriptomes and metabolomes in tissues

Nature biotechnology, 2024-07, Vol.42 (7), p.1046-1050

2024

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Simultaneous imaging of multiple neurotransmitters and neuroactive substances in the brain by desorption electrospray ionization mass spectrometry

NeuroImage (Orlando, Fla.), 2016-08, Vol.136, p.129-138

2016

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Simultaneous mass spectrometry imaging of multiple neuropeptides in the brain and alterations induced by experimental parkinsonism and L-DOPA therapy

Neurobiology of disease, 2020-04, Vol.137, p.104738, Article 104738

2020

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Association of chromosome 19 to lung cancer genotypes and phenotypes

Cancer and metastasis reviews, 2015-06, Vol.34 (2), p.217-226

2015

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Prosaposin maintains lipid homeostasis in dopamine neurons and counteracts experimental parkinsonism in rodents

Nature communications, 2023, Vol.14 (1), p.5804-5804, Article 5804

2023

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Cross-validated Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging Quantitation Protocol for a Pharmaceutical Drug and Its Drug-Target Effects in the Brain Using Time-of-Flight and Fourier Transform Ion Cyclotron Resonance Analyzers

Analytical chemistry (Washington), 2020-11, Vol.92 (21), p.14676-14684

2020

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Rapid Metabolic Profiling of 1 μL Crude Cerebrospinal Fluid by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging Can Differentiate De Novo Parkinson’s Disease

Analytical chemistry (Washington), 2023-12, Vol.95 (50), p.18352-18360

2023

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Motor effects of (−)-OSU6162 in primates with unilateral 6-hydroxydopamine lesions

European journal of pharmacology, 2000-02, Vol.389 (2), p.193-199

2000

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Future technology insight: mass spectrometry imaging as a tool in drug research and development

Naloxone reduces levodopa-induced dyskinesias and apomorphine-induced rotations in primate models of parkinsonism

On-Tissue Chemical Derivatization for Comprehensive Mapping of Brain Carboxyl and Aldehyde Metabolites by MALDI–MS Imaging

Determination of extracellular release of neurotensin in discrete rat brain regions utilizing in vivo microdialysis/electrospray mass spectrometry

Neuropeptidomics: expanding proteomics downwards

l-DOPA produces strong induction of c-fos messenger RNA in dopamine-denervated cortical and striatal areas of the common marmoset

Combining solid-phase preconcentration, capillary electrophoresis and off-line matrix-assisted laser desorption/ionization mass spectrometry: intracerebral metabolic processing of peptide E in vivo

Direct Targeted Quantitative Molecular Imaging of Neurotransmitters in Brain Tissue Sections

Repeated l-DOPA treatment increases c-fos and BDNF mRNAs in the subthalamic nucleus in the 6-OHDA rat model of Parkinson's disease

Specific molecular mass detection of endogenously released neuropeptides using in vivo microdialysis/mass spectrometry

Neuropeptidomics: MS Applied to the Discovery of Novel Peptides from the Brain

Comprehensive mapping of neurotransmitter networks by MALDI-MS imaging

An animal model for coexisting tardive dyskinesia and tardive Parkinsonism : a glutamate hypothesis for tardive dyskinesia

Mass Spectrometry Imaging, an Emerging Technology in Neuropsychopharmacology

Pyrylium Salts as Reactive Matrices for MALDI-MS Imaging of Biologically Active Primary Amines

Spatial visualization of comprehensive brain neurotransmitter systems and neuroactive substances by selective in situ chemical derivatization mass spectrometry imaging

(−)-OSU 6162 inhibits levodopa-induced dyskinesias in a monkey model of Parkinsonʼs disease

Spatial multimodal analysis of transcriptomes and metabolomes in tissues

Simultaneous imaging of multiple neurotransmitters and neuroactive substances in the brain by desorption electrospray ionization mass spectrometry

Simultaneous mass spectrometry imaging of multiple neuropeptides in the brain and alterations induced by experimental parkinsonism and L-DOPA therapy

Association of chromosome 19 to lung cancer genotypes and phenotypes

Prosaposin maintains lipid homeostasis in dopamine neurons and counteracts experimental parkinsonism in rodents

Cross-validated Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging Quantitation Protocol for a Pharmaceutical Drug and Its Drug-Target Effects in the Brain Using Time-of-Flight and Fourier Transform Ion Cyclotron Resonance Analyzers

Rapid Metabolic Profiling of 1 μL Crude Cerebrospinal Fluid by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging Can Differentiate De Novo Parkinson’s Disease

Motor effects of (−)-OSU6162 in primates with unilateral 6-hydroxydopamine lesions

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