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Transcription factor compensation during mammary gland development in E2F knockout mice

PloS one, 2018-04, Vol.13 (4), p.e0194937-e0194937

2018

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Histological subtypes of mouse mammary tumors reveal conserved relationships to human cancers

PLoS genetics, 2018-01, Vol.14 (1), p.e1007135-e1007135

2018

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Elevated phosphorylation of EGFR in NSCLC due to mutations in PTPRH

PLoS genetics, 2022-09, Vol.18 (9), p.e1010362-e1010362

2022

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Evaluating cell lines as models for metastatic breast cancer through integrative analysis of genomic data

Nature communications, 2019-05, Vol.10 (1), p.2138-12, Article 2138

2019

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The E2F Transcription Factors Regulate Tumor Development and Metastasis in a Mouse Model of Metastatic Breast Cancer

Molecular and cellular biology, 2014-09, Vol.34 (17), p.3229-3243

2014

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Metastasis is altered through multiple processes regulated by the E2F1 transcription factor

Scientific reports, 2021-05, Vol.11 (1), p.9502-9502, Article 9502

2021

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Atypical cell cycle regulation promotes mammary stem cell expansion during mammary development and tumourigenesis

Breast cancer research : BCR, 2024-06, Vol.26 (1), p.1-18, Article 106

2024

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E2F1 Drives Breast Cancer Metastasis by Regulating the Target Gene FGF13 and Altering Cell Migration

Scientific reports, 2019-07, Vol.9 (1), p.10718-13, Article 10718

2019

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How to Choose a Mouse Model of Breast Cancer, a Genomic Perspective

Journal of mammary gland biology and neoplasia, 2019-09, Vol.24 (3), p.231-243

2019

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Integrated analyses of murine breast cancer models reveal critical parallels with human disease

Nature communications, 2019-07, Vol.10 (1), p.3261-12, Article 3261

2019

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Integrative multi-omic sequencing reveals the MMTV-Myc mouse model mimics human breast cancer heterogeneity

Breast cancer research : BCR, 2023-10, Vol.25 (1), p.1-120, Article 120

2023

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Integrin-uPAR signaling leads to FRA-1 phosphorylation and enhanced breast cancer invasion

Breast cancer research : BCR, 2018-01, Vol.20 (1), p.9-9, Article 9

2018

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Triple-negative breast cancer and the potential for targeted therapy

Pharmacogenomics, 2017-11, Vol.18 (17), p.1595-1609

2017

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Reduction of Global H3K27me3 Enhances HER2/ErbB2 Targeted Therapy

Cell reports (Cambridge), 2019-10, Vol.29 (2), p.249-257.e8

2019

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Functional Redundancy between β1 and β3 Integrin in Activating the IR/Akt/mTORC1 Signaling Axis to Promote ErbB2-Driven Breast Cancer

Cell reports (Cambridge), 2019-10, Vol.29 (3), p.589-602.e6

2019

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Prediction and Genetic Demonstration of a Role for Activator E2Fs in Myc-Induced Tumors

Cancer research (Chicago, Ill.), 2011-03, Vol.71 (5), p.1924-1932

2011

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Genetic heterogeneity of Myc-induced mammary tumors reflecting diverse phenotypes including metastatic potential

Proceedings of the National Academy of Sciences - PNAS, 2009-09, Vol.106 (38), p.16387-16392

2009

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Molecular Characterization and Landscape of Breast cancer Models from a multi-omics Perspective

Journal of mammary gland biology and neoplasia, 2023-12, Vol.28 (1), p.12-12, Article 12

2023

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Studying Lymphatic Metastasis in Breast Cancer: Current Models, Strategies, and Clinical Perspectives

Journal of mammary gland biology and neoplasia, 2020-09, Vol.25 (3), p.191-203

2020

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A genomic analysis of mouse models of breast cancer reveals molecular features of mouse models and relationships to human breast cancer

Breast cancer research : BCR, 2014-01, Vol.16 (3), p.R59-R59

2014

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Low E2F2 activity is associated with high genomic instability and PARPi resistance

Scientific reports, 2020-10, Vol.10 (1), p.17948-17948, Article 17948

2020

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Patterns of cell signaling pathway activation that characterize mammary development

Development (Cambridge), 2008-07, Vol.135 (14), p.2403-2413

2008

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Identification of an Unfavorable Immune Signature in Advanced Lung Tumors from Nrf2-Deficient Mice

Antioxidants & redox signaling, 2018-12, Vol.29 (16), p.1535-1552

2018

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Utilization of genomic signatures to identify phenotype-specific drugs

PloS one, 2009-08, Vol.4 (8), p.e6772-e6772

2009

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Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras

Nature biotechnology, 2006-08, Vol.24 (8), p.1005-1015

2006

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Transcription factor compensation during mammary gland development in E2F knockout mice

Histological subtypes of mouse mammary tumors reveal conserved relationships to human cancers

Elevated phosphorylation of EGFR in NSCLC due to mutations in PTPRH

Evaluating cell lines as models for metastatic breast cancer through integrative analysis of genomic data

The E2F Transcription Factors Regulate Tumor Development and Metastasis in a Mouse Model of Metastatic Breast Cancer

Metastasis is altered through multiple processes regulated by the E2F1 transcription factor

Atypical cell cycle regulation promotes mammary stem cell expansion during mammary development and tumourigenesis

E2F1 Drives Breast Cancer Metastasis by Regulating the Target Gene FGF13 and Altering Cell Migration

How to Choose a Mouse Model of Breast Cancer, a Genomic Perspective

Integrated analyses of murine breast cancer models reveal critical parallels with human disease

Integrative multi-omic sequencing reveals the MMTV-Myc mouse model mimics human breast cancer heterogeneity

Integrin-uPAR signaling leads to FRA-1 phosphorylation and enhanced breast cancer invasion

Triple-negative breast cancer and the potential for targeted therapy

Reduction of Global H3K27me3 Enhances HER2/ErbB2 Targeted Therapy

Functional Redundancy between β1 and β3 Integrin in Activating the IR/Akt/mTORC1 Signaling Axis to Promote ErbB2-Driven Breast Cancer

Prediction and Genetic Demonstration of a Role for Activator E2Fs in Myc-Induced Tumors

Genetic heterogeneity of Myc-induced mammary tumors reflecting diverse phenotypes including metastatic potential

Molecular Characterization and Landscape of Breast cancer Models from a multi-omics Perspective

Studying Lymphatic Metastasis in Breast Cancer: Current Models, Strategies, and Clinical Perspectives

A genomic analysis of mouse models of breast cancer reveals molecular features of mouse models and relationships to human breast cancer

Low E2F2 activity is associated with high genomic instability and PARPi resistance

Patterns of cell signaling pathway activation that characterize mammary development

Identification of an Unfavorable Immune Signature in Advanced Lung Tumors from Nrf2-Deficient Mice

Utilization of genomic signatures to identify phenotype-specific drugs

Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras

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