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Is Smaller Better? Cu2+/Cu+ Coordination Chemistry and Copper-64 Radiochemical Investigation of a 1,4,7-Triazacyclononane-Based Sulfur-Rich Chelator

Inorganic chemistry, 2023-12, Vol.62 (50), p.20621-20633

2023

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Tuning the Framework of Thioether-Functionalized Polyazamacrocycles: Searching for a Chelator for Theranostic Silver Radioisotopes

Inorganic chemistry, 2023-12, Vol.62 (50), p.20777-20790

2023

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Ligand channel in pharmacologically stabilized rhodopsin

Proceedings of the National Academy of Sciences - PNAS, 2018-04, Vol.115 (14), p.3640-3645

2018

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Molecular Structure and Crystal Packing of Monofluoromethoxyarenes

European journal of organic chemistry, 2018-08, Vol.2018 (27-28), p.3724-3734

2018

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Ring opening of cyclic sulfamidates with bromophenyl metal reagents: complementarity of sulfamidates and aziridines

Tetrahedron letters, 2011-10, Vol.52 (41), p.5229-5233

2011

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Spirocyclic Oxetanes: Synthesis and Properties

Angewandte Chemie International Edition, 2008-06, Vol.47 (24), p.4512-4515

2008

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Photochemical Reactions of Prop-2-enyl and Prop-2-ynyl Substituted 4-Aminomethyl- and 4-Oxymethyl-2(5H)-furanones

Heterocycles, 2014, Vol.88 (2), p.1079

2014

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New short access to pyrrolo[2,3-c]pyridazin-6-ones via β-spirolactams

Tetrahedron letters, 2015-02, Vol.56 (6), p.772-774

2015

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Selected Replicon Variants with Low-Level In Vitro Resistance to the Hepatitis C Virus NS5B Polymerase Inhibitor PSI-6130 Lack Cross-Resistance with R1479

Antimicrobial Agents and Chemotherapy, 2008-12, Vol.52 (12), p.4356-4369

2008

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Discovery of 4‑Aryl-5,6,7,8-tetrahydroisoquinolines as Potent, Selective, and Orally Active Aldosterone Synthase (CYP11B2) Inhibitors: In Vivo Evaluation in Rodents and Cynomolgus Monkeys

Journal of medicinal chemistry, 2015-10, Vol.58 (20), p.8054-8065

2015

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An Intramolecular [2 + 2] Photocycloaddition Approach to Conformationally Restricted Bis-Pyrrolidines

Journal of organic chemistry, 2014-08, Vol.79 (15), p.7152-7161

2014

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CELLOPT: improved unit‐cell parameters for electron diffraction data of small‐molecule crystals

Journal of applied crystallography, 2022-06, Vol.55 (3), p.647-655

2022

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Iterative One Pot Reactions of a Chiral Sulfamidate with 2,4,6-Trichloropyridine: Regiocontrolled Synthesis of Linear and Angular Chiral Dipyrrolidino Pyridines

Heterocycles, 2012, Vol.85 (1), p.65

2012

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Synthesis of Annulated Pyridines by Intramolecular Inverse-Electron-Demand Hetero-Diels-Alder Reaction under Superheated Continuous Flow Conditions

European Journal of Organic Chemistry, 2012-01, Vol.2012 (1), p.47-52

2012

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Copper Coordination Chemistry of Sulfur Pendant Cyclen Derivatives: An Attempt to Hinder the Reductive-Induced Demetalation in 64/67Cu Radiopharmaceuticals

Inorganic chemistry, 2021-08, Vol.60 (15), p.11530-11547

2021

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Modulation of Pharmacologically Relevant Properties of Piperidine Derivatives by Functional Groups in an Equatorial or Axial β‐Position to the Amino Group

Chembiochem : a European journal of chemical biology, 2020-01, Vol.21 (1-2), p.212-234

2020

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Piperidinyl-nicotinamides as potent and selective somatostatin receptor subtype 5 antagonists

Bioorganic & medicinal chemistry letters, 2010-08, Vol.20 (15), p.4521-4525

2010

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Novel Series of Dihydropyridinone P2X7 Receptor Antagonists

Journal of medicinal chemistry, 2015-11, Vol.58 (21), p.8413-8426

2015

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Cytochrome P450-Mediated Metabolism and CYP Inhibition for the Synthetic Peroxide Antimalarial OZ439

ACS infectious diseases, 2021-07, Vol.7 (7), p.1885-1893

2021

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Characterization of the two major CYP450 metabolites of ozonide (1,2,4-trioxolane) OZ277

Bioorganic & medicinal chemistry, 2008-03, Vol.18 (5), p.1555-1558

2008

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Discovery of potent, balanced and orally active dual NK1/NK3 receptor ligands

Bioorganic & medicinal chemistry letters, 2010-06, Vol.20 (11), p.3405-3408

2010

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Two Distinct Conformations of GABA Locked by Embedding in the Bicyclo[3.1.0]hexane Core Structure

ChemMedChem, 2011-10, Vol.6 (10), p.1792-1795

2011

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Benzoxazole piperidines as selective and potent somatostatin receptor subtype 5 antagonists

Bioorganic & medicinal chemistry letters, 2009-11, Vol.19 (21), p.6106-6113

2009

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Libraries on Oxetane δ-Amino Acid Scaffolds: Syntheses and Evaluation of Physicochemical and Metabolic Properties

Journal of carbohydrate chemistry, 2011-09, Vol.30 (7-9), p.498-548

2011

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Is Smaller Better? Cu2+/Cu+ Coordination Chemistry and Copper-64 Radiochemical Investigation of a 1,4,7-Triazacyclononane-Based Sulfur-Rich Chelator

Tuning the Framework of Thioether-Functionalized Polyazamacrocycles: Searching for a Chelator for Theranostic Silver Radioisotopes

Ligand channel in pharmacologically stabilized rhodopsin

Molecular Structure and Crystal Packing of Monofluoromethoxyarenes

Ring opening of cyclic sulfamidates with bromophenyl metal reagents: complementarity of sulfamidates and aziridines

Spirocyclic Oxetanes: Synthesis and Properties

Photochemical Reactions of Prop-2-enyl and Prop-2-ynyl Substituted 4-Aminomethyl- and 4-Oxymethyl-2(5H)-furanones

New short access to pyrrolo[2,3-c]pyridazin-6-ones via β-spirolactams

Selected Replicon Variants with Low-Level In Vitro Resistance to the Hepatitis C Virus NS5B Polymerase Inhibitor PSI-6130 Lack Cross-Resistance with R1479

Discovery of 4‑Aryl-5,6,7,8-tetrahydroisoquinolines as Potent, Selective, and Orally Active Aldosterone Synthase (CYP11B2) Inhibitors: In Vivo Evaluation in Rodents and Cynomolgus Monkeys

An Intramolecular [2 + 2] Photocycloaddition Approach to Conformationally Restricted Bis-Pyrrolidines

CELLOPT: improved unit‐cell parameters for electron diffraction data of small‐molecule crystals

Iterative One Pot Reactions of a Chiral Sulfamidate with 2,4,6-Trichloropyridine: Regiocontrolled Synthesis of Linear and Angular Chiral Dipyrrolidino Pyridines

Synthesis of Annulated Pyridines by Intramolecular Inverse-Electron-Demand Hetero-Diels-Alder Reaction under Superheated Continuous Flow Conditions

Copper Coordination Chemistry of Sulfur Pendant Cyclen Derivatives: An Attempt to Hinder the Reductive-Induced Demetalation in 64/67Cu Radiopharmaceuticals

Modulation of Pharmacologically Relevant Properties of Piperidine Derivatives by Functional Groups in an Equatorial or Axial β‐Position to the Amino Group

RG7774 (Vicasinabin), an orally bioavailable cannabinoid receptor 2 (CB2R) agonist, decreases retinal vascular permeability, leukocyte adhesion, and ocular inflammation in animal models

Piperidinyl-nicotinamides as potent and selective somatostatin receptor subtype 5 antagonists

Novel Series of Dihydropyridinone P2X7 Receptor Antagonists

Cytochrome P450-Mediated Metabolism and CYP Inhibition for the Synthetic Peroxide Antimalarial OZ439

Characterization of the two major CYP450 metabolites of ozonide (1,2,4-trioxolane) OZ277

Discovery of potent, balanced and orally active dual NK1/NK3 receptor ligands

Two Distinct Conformations of GABA Locked by Embedding in the Bicyclo[3.1.0]hexane Core Structure

Benzoxazole piperidines as selective and potent somatostatin receptor subtype 5 antagonists

Libraries on Oxetane δ-Amino Acid Scaffolds: Syntheses and Evaluation of Physicochemical and Metabolic Properties

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