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Diverse stresses dramatically alter genome-wide p53 binding and transactivation landscape in human cancer cells

Nucleic acids research, 2013-08, Vol.41 (15), p.7286

2013

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Mutant TP53 Posttranslational Modifications: Challenges and Opportunities

Human mutation, 2014-06, Vol.35 (6), p.738-755

2014

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Wip1 Phosphatase Modulates ATM-Dependent Signaling Pathways

Molecular cell, 2006-09, Vol.23 (5), p.757-764

2006

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Distinct p53 genomic binding patterns in normal and cancer-derived human cells

Cell cycle (Georgetown, Tex.), 2011-12, Vol.10 (24), p.4237-4249

2011

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Phosphorylation Site Interdependence of Human p53 Post-translational Modifications in Response to Stress

The Journal of biological chemistry, 2003-09, Vol.278 (39), p.37536-37544

2003

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Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity

Nature genetics, 2002-06, Vol.31 (2), p.210-215

2002

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Posttranslational modification of p53: cooperative integrators of function

Cold Spring Harbor perspectives in biology, 2009-12, Vol.1 (6), p.a000950-a000950

2009

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Regulation of ATM/p53-dependent suppression of myc-induced lymphomas by Wip1 phosphatase

The Journal of experimental medicine, 2006-12, Vol.203 (13), p.2793-2799

2006

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Post‐translational modifications and activation of p53 by genotoxic stresses

European journal of biochemistry, 2001-05, Vol.268 (10), p.2764-2772

2001

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Acetylation of Mouse p53 at Lysine 317 Negatively Regulates p53 Apoptotic Activities after DNA Damage

Molecular and Cellular Biology, 2006-09, Vol.26 (18), p.6859-6869

2006

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The Wip1 Phosphatase PPM1D Dephosphorylates SQ/TQ Motifs in Checkpoint Substrates Phosphorylated by PI3K-like Kinases

Biochemistry (Easton), 2007-11, Vol.46 (44), p.12594-12603

2007

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Phosphorylation of Murine p53 at Ser-18 Regulates the p53 Responses to DNA Damage

Proceedings of the National Academy of Sciences - PNAS, 2000-10, Vol.97 (22), p.11936-11941

2000

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Revealing a human p53 universe

Nucleic acids research, 2018-09, Vol.46 (16), p.8153

2018

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The Epstein-Barr Virus Immediate-Early Protein BZLF1 Regulates p53 Function through Multiple Mechanisms

Journal of Virology, 2002-12, Vol.76 (24), p.12503-12512

2002

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Phosphorylation of Serine 392 Stabilizes the Tetramer Formation of Tumor Suppressor Protein p53

Biochemistry (Easton), 1997-08, Vol.36 (33), p.10117-10124

1997

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Mutation of Mouse p53 Ser23 and the Response to DNA Damage

Molecular and Cellular Biology, 2002-04, Vol.22 (8), p.2441-2449

2002

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Cancer-associated p53 tetramerization domain mutants: quantitative analysis reveals a low threshold for tumor suppressor inactivation

The Journal of biological chemistry, 2011-01, Vol.286 (1), p.252-258

2011

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p53 vs. ISG15: Stop, you're killing me

Cell cycle (Georgetown, Tex.), 2014-07, Vol.13 (14), p.2160-2161

Anderson, Carl W.

2014

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The novel p53 target TNFAIP8 variant 2 is increased in cancer and offsets p53-dependent tumor suppression

Cell death and differentiation, 2017-01, Vol.24 (1), p.181-191

2017

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Inactivation of the Wip1 phosphatase inhibits mammary tumorigenesis through p38 MAPK-mediated activation of the p16(Ink4a)-p19(Arf) pathway

Nature genetics, 2004-04, Vol.36 (4), p.343

2004

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The isoflavonoids genistein and quercetin activate different stress signaling pathways as shown by analysis of site-specific phosphorylation of ATM, p53 and histone H2AX

DNA repair, 2004-03, Vol.3 (3), p.235-244

2004

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DNA damage activates p53 through a phosphorylation-acetylation cascade

Genes & development, 1998-09, Vol.12 (18), p.2831-2841

1998

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Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation

The EMBO journal, 1999-12, Vol.18 (23), p.6845-6854

1999

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ATM mediates phosphorylation at multiple p53 sites, including Ser(46), in response to ionizing radiation

The Journal of biological chemistry, 2002-04, Vol.277 (15), p.12491-12494

2002

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Development of a Substrate-Based Cyclic Phosphopeptide Inhibitor of Protein Phosphatase 2Cδ, Wip1

Biochemistry (Easton), 2006-11, Vol.45 (44), p.13193-13202

2006

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Diverse stresses dramatically alter genome-wide p53 binding and transactivation landscape in human cancer cells

Mutant TP53 Posttranslational Modifications: Challenges and Opportunities

Wip1 Phosphatase Modulates ATM-Dependent Signaling Pathways

Distinct p53 genomic binding patterns in normal and cancer-derived human cells

Phosphorylation Site Interdependence of Human p53 Post-translational Modifications in Response to Stress

Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity

Posttranslational modification of p53: cooperative integrators of function

Regulation of ATM/p53-dependent suppression of myc-induced lymphomas by Wip1 phosphatase

Post‐translational modifications and activation of p53 by genotoxic stresses

Acetylation of Mouse p53 at Lysine 317 Negatively Regulates p53 Apoptotic Activities after DNA Damage

The Wip1 Phosphatase PPM1D Dephosphorylates SQ/TQ Motifs in Checkpoint Substrates Phosphorylated by PI3K-like Kinases

Phosphorylation of Murine p53 at Ser-18 Regulates the p53 Responses to DNA Damage

Revealing a human p53 universe

The Epstein-Barr Virus Immediate-Early Protein BZLF1 Regulates p53 Function through Multiple Mechanisms

Phosphorylation of Serine 392 Stabilizes the Tetramer Formation of Tumor Suppressor Protein p53

Mutation of Mouse p53 Ser23 and the Response to DNA Damage

Cancer-associated p53 tetramerization domain mutants: quantitative analysis reveals a low threshold for tumor suppressor inactivation

p53 vs. ISG15: Stop, you're killing me

The novel p53 target TNFAIP8 variant 2 is increased in cancer and offsets p53-dependent tumor suppression

Inactivation of the Wip1 phosphatase inhibits mammary tumorigenesis through p38 MAPK-mediated activation of the p16(Ink4a)-p19(Arf) pathway

The isoflavonoids genistein and quercetin activate different stress signaling pathways as shown by analysis of site-specific phosphorylation of ATM, p53 and histone H2AX

DNA damage activates p53 through a phosphorylation-acetylation cascade

Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation

ATM mediates phosphorylation at multiple p53 sites, including Ser(46), in response to ionizing radiation

Development of a Substrate-Based Cyclic Phosphopeptide Inhibitor of Protein Phosphatase 2Cδ, Wip1

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