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Toxicity Testing in the 21st Century: Bringing the Vision to Life

Toxicological sciences, 2009-02, Vol.107 (2), p.324-330

2009

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Ultrasensitive response motifs: basic amplifiers in molecular signalling networks

Open biology, 2013-04, Vol.3 (4), p.130031-130031

2013

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Toxicity testing in the 21 century: defining new risk assessment approaches based on perturbation of intracellular toxicity pathways

PloS one, 2011, Vol.6 (6), p.e20887

2011

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Hepatocyte-specific Nrf2 deficiency mitigates high-fat diet-induced hepatic steatosis: Involvement of reduced PPARγ expression

Redox biology, 2020-02, Vol.30, p.101412, Article 101412

2020

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Adipose Deficiency of Nrf2 in ob/ob Mice Results in Severe Metabolic Syndrome

Diabetes (New York, N.Y.), 2013-03, Vol.62 (3), p.845-854

2013

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A deterministic map of Waddington's epigenetic landscape for cell fate specification

BMC systems biology, 2011-05, Vol.5 (67), p.85-85

2011

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Adaptive Posttranslational Control in Cellular Stress Response Pathways and Its Relationship to Toxicity Testing and Safety Assessment

Toxicological sciences, 2015-10, Vol.147 (2), p.302-316

2015

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Integration of Dosimetry, Exposure, and High-Throughput Screening Data in Chemical Toxicity Assessment

Toxicological sciences, 2012-01, Vol.125 (1), p.157-174

2012

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Adipocyte-specific deficiency of Nfe2l1 disrupts plasticity of white adipose tissues and metabolic homeostasis in mice

Biochemical and biophysical research communications, 2018-09, Vol.503 (1), p.264-270

2018

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Temporal concordance between apical and transcriptional points of departure for chemical risk assessment

Toxicological sciences, 2013-07, Vol.134 (1), p.180-194

2013

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Reactive Oxygen Species as a Signal in Glucose-Stimulated Insulin Secretion

Diabetes (New York, N.Y.), 2007-07, Vol.56 (7), p.1783-1791

2007

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ROS signaling, oxidative stress and Nrf2 in pancreatic beta-cell function

Toxicology and applied pharmacology, 2010-04, Vol.244 (1), p.77-83

2010

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Co-culture of Hepatocytes and Kupffer Cells as an In Vitro Model of Inflammation and Drug-Induced Hepatotoxicity

Journal of pharmaceutical sciences, 2016-02, Vol.105 (2), p.950-964

2016

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Genetic variability in a frozen batch of MCF-7 cells invisible in routine authentication affecting cell function

Scientific reports, 2016-07, Vol.6 (1), p.28994-28994, Article 28994

2016

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Long isoforms of NRF1 negatively regulate adipogenesis via suppression of PPARγ expression

Redox biology, 2020-02, Vol.30, p.101414, Article 101414

2020

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Perfluoroalkyl Acids and Related Chemistries—Toxicokinetics and Modes of Action

Toxicological sciences, 2008-03, Vol.102 (1), p.3-14

2008

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Low-Level Arsenic Impairs Glucose-Stimulated Insulin Secretion in Pancreatic Beta Cells: Involvement of Cellular Adaptive Response to Oxidative Stress

Environmental health perspectives, 2010-06, Vol.118 (6), p.864-870

2010

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Dose response relationship in anti-stress gene regulatory networks

PLoS computational biology, 2007-03, Vol.3 (3), p.e24

2007

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Iodoacetic Acid Activates Nrf2-Mediated Antioxidant Response in Vitro and in Vivo

Environmental science & technology, 2014-11, Vol.48 (22), p.13478-13488

2014

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Adverse Outcome Pathways can drive non-animal approaches for safety assessment

Journal of applied toxicology, 2015-09, Vol.35 (9), p.971-975

2015

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Estimating provisional margins of exposure for data-poor chemicals using high-throughput computational methods

Frontiers in pharmacology, 2022-10, Vol.13, p.980747-980747

2022

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Toxicity Testing in the 21st Century: Implications for Human Health Risk Assessment

Risk analysis, 2009-04, Vol.29 (4), p.474-479

2009

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Association between arsenic suppression of adipogenesis and induction of CHOP10 via the endoplasmic reticulum stress response

Environmental health perspectives, 2013-02, Vol.121 (2), p.237-243

2013

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Physiologically Based Pharmacokinetic Modeling of Fetal and Neonatal Manganese Exposure in Humans: Describing Manganese Homeostasis during Development

Toxicological sciences, 2011-08, Vol.122 (2), p.297-316

2011

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Prolonged inorganic arsenite exposure suppresses insulin-stimulated AKT S473 phosphorylation and glucose uptake in 3T3-L1 adipocytes: Involvement of the adaptive antioxidant response

Biochemical and biophysical research communications, 2011-04, Vol.407 (2), p.360-365

2011

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Toxicity Testing in the 21st Century: Bringing the Vision to Life

Ultrasensitive response motifs: basic amplifiers in molecular signalling networks

Toxicity testing in the 21 century: defining new risk assessment approaches based on perturbation of intracellular toxicity pathways

Hepatocyte-specific Nrf2 deficiency mitigates high-fat diet-induced hepatic steatosis: Involvement of reduced PPARγ expression

Adipose Deficiency of Nrf2 in ob/ob Mice Results in Severe Metabolic Syndrome

A deterministic map of Waddington's epigenetic landscape for cell fate specification

Adaptive Posttranslational Control in Cellular Stress Response Pathways and Its Relationship to Toxicity Testing and Safety Assessment

Integration of Dosimetry, Exposure, and High-Throughput Screening Data in Chemical Toxicity Assessment

Adipocyte-specific deficiency of Nfe2l1 disrupts plasticity of white adipose tissues and metabolic homeostasis in mice

Temporal concordance between apical and transcriptional points of departure for chemical risk assessment

Reactive Oxygen Species as a Signal in Glucose-Stimulated Insulin Secretion

ROS signaling, oxidative stress and Nrf2 in pancreatic beta-cell function

Co-culture of Hepatocytes and Kupffer Cells as an In Vitro Model of Inflammation and Drug-Induced Hepatotoxicity

Genetic variability in a frozen batch of MCF-7 cells invisible in routine authentication affecting cell function

Long isoforms of NRF1 negatively regulate adipogenesis via suppression of PPARγ expression

Perfluoroalkyl Acids and Related Chemistries—Toxicokinetics and Modes of Action

Low-Level Arsenic Impairs Glucose-Stimulated Insulin Secretion in Pancreatic Beta Cells: Involvement of Cellular Adaptive Response to Oxidative Stress

Dose response relationship in anti-stress gene regulatory networks

Iodoacetic Acid Activates Nrf2-Mediated Antioxidant Response in Vitro and in Vivo

Adverse Outcome Pathways can drive non-animal approaches for safety assessment

Estimating provisional margins of exposure for data-poor chemicals using high-throughput computational methods

Toxicity Testing in the 21st Century: Implications for Human Health Risk Assessment

Association between arsenic suppression of adipogenesis and induction of CHOP10 via the endoplasmic reticulum stress response

Physiologically Based Pharmacokinetic Modeling of Fetal and Neonatal Manganese Exposure in Humans: Describing Manganese Homeostasis during Development

Prolonged inorganic arsenite exposure suppresses insulin-stimulated AKT S473 phosphorylation and glucose uptake in 3T3-L1 adipocytes: Involvement of the adaptive antioxidant response

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