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Soluble Klotho Protects against Uremic Cardiomyopathy Independently of Fibroblast Growth Factor 23 and Phosphate

Journal of the American Society of Nephrology, 2015-05, Vol.26 (5), p.1150-1160

2015

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Cardioprotection by Klotho through downregulation of TRPC6 channels in the mouse heart

Nature communications, 2012, Vol.3 (1), p.1238-1238, Article 1238

2012

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New Insights into the Mechanism of Action of Soluble Klotho

Frontiers in endocrinology (Lausanne), 2017-11, Vol.8, p.323-323

2017

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Soluble klotho regulates TRPC6 calcium signaling via lipid rafts, independent of the FGFR‐FGF23 pathway

The FASEB journal, 2019-08, Vol.33 (8), p.9182-9193

2019

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Inhibition of TRPC6 channels ameliorates renal fibrosis and contributes to renal protection by soluble klotho

Kidney international, 2017-04, Vol.91 (4), p.830-841

2017

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Munc13 mediates klotho-inhibitable diacylglycerol-stimulated exocytotic insertion of pre-docked TRPC6 vesicles

PloS one, 2020-03, Vol.15 (3), p.e0229799-e0229799

2020

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Soluble klotho binds monosialoganglioside to regulate membrane microdomains and growth factor signaling

Proceedings of the National Academy of Sciences - PNAS, 2017-01, Vol.114 (4), p.752-757

2017

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Modeled structural basis for the recognition of α2–3‐sialyllactose by soluble Klotho

The FASEB journal, 2017-08, Vol.31 (8), p.3574-3586

2017

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OSR1 regulates a subset of inward rectifier potassium channels via a binding motif variant

Proceedings of the National Academy of Sciences - PNAS, 2018-04, Vol.115 (15), p.3840-3845

2018

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Chloride oscillation in pacemaker neurons regulates circadian rhythms through a chloride-sensing WNK kinase signaling cascade

Current biology, 2022-03, Vol.32 (6), p.1429-1438.e6

2022

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Klotho Up-regulates Renal Calcium Channel Transient Receptor Potential Vanilloid 5 (TRPV5) by Intra- and Extracellular N-glycosylation-dependent Mechanisms

The Journal of biological chemistry, 2014-12, Vol.289 (52), p.35849-35857

2014

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Gentamicin induces calciuresis by blocking TRPV5

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

2022

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Ghrelin enhances tubular magnesium absorption in the kidney

Frontiers in physiology, 2024-04, Vol.15, p.1363708-1363708

2024

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DGKE Variants Cause a Glomerular Microangiopathy That Mimics Membranoproliferative GN

Journal of the American Society of Nephrology, 2013-03, Vol.24 (3), p.377-384

2013

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WNK1 Promotes PIP2 Synthesis to Coordinate Growth Factor and GPCR-Gq Signaling

Current biology, 2011-12, Vol.21 (23), p.1979-1987

2011

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5E- and 5Z-farnesylacetones from Sargassum siliquastrum as novel selective L-type calcium channel blockers

Vascular pharmacology, 2013-04, Vol.58 (4), p.299-306

2013

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Mucin 1 Stimulates TRPM6 Single-Channel Activity and Cell Surface Abundance by Impairing Dynamin-Dependent TRPM6 Endocytosis: TH-OR58

Journal of the American Society of Nephrology, 2024-10, Vol.35 (10S)

2024

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Developing New Therapies for Autosomal Dominant Tubulointerstitial Kidney Disease Caused by Uromodulin Mutations by Screening a Small Molecule Library: SA-PO645

Journal of the American Society of Nephrology, 2024-10, Vol.35 (10S)

2024

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Insulin Receptor Substrate 4 (IRS4) Contributes to Hypomagnesemia by Mediating the Insulin Effect on the Renal Magnesium Channel TRPM6: FR-OR46

Journal of the American Society of Nephrology, 2022-11, Vol.33 (11S), p.30-30

2022

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Protein‐Protein Interaction Prediction Yields WNK‐SPAK/OSR1 Pathway as Regulator of Kir2.1 and Kir2.3 K+ Channels

The FASEB journal, 2018-04, Vol.32 (S1), p.533.12-533.12

2018

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Gentamicin Inhibits Ca2+ Channel TRPV5 and Induces Calciuresis Independent of the Calcium-Sensing Receptor–Claudin-14 Pathway

Journal of the American Society of Nephrology, 2022-03, Vol.33 (3), p.547-564

2022

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Gentamicin Inhibits Ca 2+ Channel TRPV5 and Induces Calciuresis Independent of the Calcium-Sensing Receptor-Claudin-14 Pathway

Journal of the American Society of Nephrology, 2022-03, Vol.33 (3), p.547

2022

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5 E - and 5 Z -farnesylacetones from Sargassum siliquastrum as novel selective L-type calcium channel blockers

Vascular pharmacology, 2013, Vol.58 (4), p.299-306

2013

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Innovative delivery of siRNA to solid tumors by super carbonate apatite

PloS one, 2015-03, Vol.10 (3), p.e0116022-e0116022

2015

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Molecular mechanism of RBP4 on the basis of insulin signaling pathway in primary hepatocytes

The FASEB journal, 2010-04, Vol.24 (S1), p.889.3-889.3

2010

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Soluble Klotho Protects against Uremic Cardiomyopathy Independently of Fibroblast Growth Factor 23 and Phosphate

Cardioprotection by Klotho through downregulation of TRPC6 channels in the mouse heart

New Insights into the Mechanism of Action of Soluble Klotho

Soluble klotho regulates TRPC6 calcium signaling via lipid rafts, independent of the FGFR‐FGF23 pathway

Inhibition of TRPC6 channels ameliorates renal fibrosis and contributes to renal protection by soluble klotho

Munc13 mediates klotho-inhibitable diacylglycerol-stimulated exocytotic insertion of pre-docked TRPC6 vesicles

Soluble klotho binds monosialoganglioside to regulate membrane microdomains and growth factor signaling

Modeled structural basis for the recognition of α2–3‐sialyllactose by soluble Klotho

OSR1 regulates a subset of inward rectifier potassium channels via a binding motif variant

Chloride oscillation in pacemaker neurons regulates circadian rhythms through a chloride-sensing WNK kinase signaling cascade

Klotho Up-regulates Renal Calcium Channel Transient Receptor Potential Vanilloid 5 (TRPV5) by Intra- and Extracellular N-glycosylation-dependent Mechanisms

Gentamicin induces calciuresis by blocking TRPV5

Ghrelin enhances tubular magnesium absorption in the kidney

DGKE Variants Cause a Glomerular Microangiopathy That Mimics Membranoproliferative GN

WNK1 Promotes PIP2 Synthesis to Coordinate Growth Factor and GPCR-Gq Signaling

5E- and 5Z-farnesylacetones from Sargassum siliquastrum as novel selective L-type calcium channel blockers

Mucin 1 Stimulates TRPM6 Single-Channel Activity and Cell Surface Abundance by Impairing Dynamin-Dependent TRPM6 Endocytosis: TH-OR58

Developing New Therapies for Autosomal Dominant Tubulointerstitial Kidney Disease Caused by Uromodulin Mutations by Screening a Small Molecule Library: SA-PO645

Insulin Receptor Substrate 4 (IRS4) Contributes to Hypomagnesemia by Mediating the Insulin Effect on the Renal Magnesium Channel TRPM6: FR-OR46

Protein‐Protein Interaction Prediction Yields WNK‐SPAK/OSR1 Pathway as Regulator of Kir2.1 and Kir2.3 K+ Channels

Gentamicin Inhibits Ca2+ Channel TRPV5 and Induces Calciuresis Independent of the Calcium-Sensing Receptor–Claudin-14 Pathway

Gentamicin Inhibits Ca 2+ Channel TRPV5 and Induces Calciuresis Independent of the Calcium-Sensing Receptor-Claudin-14 Pathway

5 E - and 5 Z -farnesylacetones from Sargassum siliquastrum as novel selective L-type calcium channel blockers

Innovative delivery of siRNA to solid tumors by super carbonate apatite

Molecular mechanism of RBP4 on the basis of insulin signaling pathway in primary hepatocytes

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