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Tamoxifen Pharmacogenomics: The Role of CYP2D6 as a Predictor of Drug Response

Clinical pharmacology and therapeutics, 2008-01, Vol.83 (1), p.160-166

2008

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Association between CYP2D6 polymorphisms and outcomes among women with early stage breast cancer treated with tamoxifen

JAMA : the journal of the American Medical Association, 2009-10, Vol.302 (13), p.1429

2009

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Pharmacogenetics of Tamoxifen Biotransformation Is Associated With Clinical Outcomes of Efficacy and Hot Flashes

Journal of clinical oncology, 2005-12, Vol.23 (36), p.9312-9318

2005

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Phase II Trial of Vorinostat in Recurrent Glioblastoma Multiforme: A North Central Cancer Treatment Group Study

Journal of clinical oncology, 2009-04, Vol.27 (12), p.2052-2058

2009

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The Hsp90 chaperone complex as a novel target for cancer therapy

Annals of oncology, 2003-08, Vol.14 (8), p.1169-1176

2003

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Gemcitabine Pharmacogenomics: Cytidine Deaminase and Deoxycytidylate Deaminase Gene Resequencing and Functional Genomics

Clinical cancer research, 2006-03, Vol.12 (6), p.1794-1803

2006

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Preclinical Pharmacology and Toxicology of Intravenous MV-NIS, an Oncolytic Measles Virus Administered With or Without Cyclophosphamide

Clinical pharmacology and therapeutics, 2007-12, Vol.82 (6), p.700-710

2007

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Characterization of "Peak E," a Novel Amino Acid Associated with Eosinophilia-Myalgia Syndrome

Science (American Association for the Advancement of Science), 1990-12, Vol.250 (4988), p.1707-1708

1990

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Epidermal growth factor receptor and activated epidermal growth factor receptor expression in gastrointestinal carcinoids and pancreatic endocrine carcinomas

Modern pathology, 2005-10, Vol.18 (10), p.1329-1335

2005

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Abstract P1-08-03: Identification and characterization of a novel endoxifen substrate, PKCβ1, and its interaction with the estrogen receptor

Cancer research (Chicago, Ill.), 2017-02, Vol.77 (4_Supplement), p.P1-P1-08-03

2017

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Phase I Trial and Pharmacokinetics of Gemcitabine in Children With Advanced Solid Tumors

Journal of clinical oncology, 2004-06, Vol.22 (12), p.2445-2451

2004

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Abstract PD2-03: Final results of a first-in-human phase I study of the tamoxifen (TAM) metabolite, Z-Endoxifen hydrochloride (Z-Endx) in women with aromatase inhibitor (AI) refractory metastatic breast cancer (MBC) (NCT01327781)

Cancer research (Chicago, Ill.), 2016-02, Vol.76 (4_Supplement), p.PD2-03-PD2-03

2016

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Phase 1 Trial of Flavopiridol Combined with Cisplatin or Carboplatin in Patients with Advanced Malignancies with the Assessment of Pharmacokinetic and Pharmacodynamic End Points

Clinical cancer research, 2005-08, Vol.11 (16), p.5935-5941

2005

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Metabolic Activation of Dacarbazine by Human Cytochromes P450: The Role of CYP1A1, CYP1A2, and CYP2E1

Clinical cancer research, 1999-08, Vol.5 (8), p.2192-2197

1999

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Abstract PD3-4: A first-in-human phase I study of the tamoxifen (TAM) metabolite, Z-endoxifen hydrochloride (Z-Endx) in women with aromatase inhibitor (AI) refractory metastatic breast cancer (MBC) (NCT01327781)

Cancer research (Chicago, Ill.), 2013-12, Vol.73 (24_Supplement), p.PD3-4-PD3-4

2013

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Phase I Clinical and Pharmacokinetic Study of Flavopiridol in Children With Refractory Solid Tumors: A Children's Oncology Group Study

Journal of clinical oncology, 2005-12, Vol.23 (36), p.9179-9186

2005

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CYP1A1 activation of aminoflavone leads to DNA damage in human tumor cell lines

Cancer chemotherapy and pharmacology, 2006-05, Vol.57 (5), p.569-576

2006

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Activation of the Antitumor Agent Aminoflavone (NSC 686288) Is Mediated by Induction of Tumor Cell Cytochrome P450 1A1/1A2

Molecular pharmacology, 2002-07, Vol.62 (1), p.143-153

2002

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Lack of Mutations in EGFR in Gastroenteropancreatic Neuroendocrine Tumors

The New England journal of medicine, 2005-07, Vol.353 (2), p.209-210

2005

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Primer on Medical Genomics: Part XII: Pharmacogenomics—General Principles With Cancer as a Model

Mayo Clinic proceedings, 2004-03, Vol.79 (3), p.376-384

2004

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Phase I Trial of Dolastatin-10 (NSC 376128) in Patients with Advanced Solid Tumors

Clinical cancer research, 1999-03, Vol.5 (3), p.525-531

1999

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The Aromatic-l-Amino Acid Decarboxylase Inhibitor Carbidopa Is Selectively Cytotoxic to Human Pulmonary Carcinoid and Small Cell Lung Carcinoma Cells

Clinical cancer research, 2000-11, Vol.6 (11), p.4365-4372

2000

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Phase I and Pharmacologic Study of Infusional Topotecan and Carboplatin in Relapsed and Refractory Acute Leukemia

Clinical cancer research, 2005-09, Vol.11 (18), p.6641-6649

2005

Volltextzugriff (PDF)

Phase I and Pharmacokinetic Study of Two Different Schedules of Oxaliplatin, Irinotecan, Fluorouracil, and Leucovorin in Patients With Solid Tumors

Journal of clinical oncology, 2003-10, Vol.21 (20), p.3761-3769

2003

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Museology Interrupted

Museum international, 2005-09, Vol.57 (3), p.44-51

Ames, Michael M.

2005

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Tamoxifen Pharmacogenomics: The Role of CYP2D6 as a Predictor of Drug Response

Association between CYP2D6 polymorphisms and outcomes among women with early stage breast cancer treated with tamoxifen

Pharmacogenetics of Tamoxifen Biotransformation Is Associated With Clinical Outcomes of Efficacy and Hot Flashes

Phase II Trial of Vorinostat in Recurrent Glioblastoma Multiforme: A North Central Cancer Treatment Group Study

The Hsp90 chaperone complex as a novel target for cancer therapy

Gemcitabine Pharmacogenomics: Cytidine Deaminase and Deoxycytidylate Deaminase Gene Resequencing and Functional Genomics

Preclinical Pharmacology and Toxicology of Intravenous MV-NIS, an Oncolytic Measles Virus Administered With or Without Cyclophosphamide

Characterization of "Peak E," a Novel Amino Acid Associated with Eosinophilia-Myalgia Syndrome

Epidermal growth factor receptor and activated epidermal growth factor receptor expression in gastrointestinal carcinoids and pancreatic endocrine carcinomas

Abstract P1-08-03: Identification and characterization of a novel endoxifen substrate, PKCβ1, and its interaction with the estrogen receptor

Phase I Trial and Pharmacokinetics of Gemcitabine in Children With Advanced Solid Tumors

Abstract PD2-03: Final results of a first-in-human phase I study of the tamoxifen (TAM) metabolite, Z-Endoxifen hydrochloride (Z-Endx) in women with aromatase inhibitor (AI) refractory metastatic breast cancer (MBC) (NCT01327781)

Phase 1 Trial of Flavopiridol Combined with Cisplatin or Carboplatin in Patients with Advanced Malignancies with the Assessment of Pharmacokinetic and Pharmacodynamic End Points

Metabolic Activation of Dacarbazine by Human Cytochromes P450: The Role of CYP1A1, CYP1A2, and CYP2E1

Abstract PD3-4: A first-in-human phase I study of the tamoxifen (TAM) metabolite, Z-endoxifen hydrochloride (Z-Endx) in women with aromatase inhibitor (AI) refractory metastatic breast cancer (MBC) (NCT01327781)

Phase I Clinical and Pharmacokinetic Study of Flavopiridol in Children With Refractory Solid Tumors: A Children's Oncology Group Study

CYP1A1 activation of aminoflavone leads to DNA damage in human tumor cell lines

Activation of the Antitumor Agent Aminoflavone (NSC 686288) Is Mediated by Induction of Tumor Cell Cytochrome P450 1A1/1A2

Lack of Mutations in EGFR in Gastroenteropancreatic Neuroendocrine Tumors

Primer on Medical Genomics: Part XII: Pharmacogenomics—General Principles With Cancer as a Model

Phase I Trial of Dolastatin-10 (NSC 376128) in Patients with Advanced Solid Tumors

The Aromatic-l-Amino Acid Decarboxylase Inhibitor Carbidopa Is Selectively Cytotoxic to Human Pulmonary Carcinoid and Small Cell Lung Carcinoma Cells

Phase I and Pharmacologic Study of Infusional Topotecan and Carboplatin in Relapsed and Refractory Acute Leukemia

Phase I and Pharmacokinetic Study of Two Different Schedules of Oxaliplatin, Irinotecan, Fluorouracil, and Leucovorin in Patients With Solid Tumors

Museology Interrupted

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