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Ca2+ signaling and regulation of fluid secretion in salivary gland acinar cells

Cell calcium (Edinburgh), 2014-06, Vol.55 (6), p.297-305

Ambudkar, Indu S

2014

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Local Ca²+ entry via Orai1 regulates plasma membrane recruitment of TRPC1 and controls cytosolic Ca²+ signals required for specific cell functions

PLoS biology, 2011-03, Vol.9 (3), p.e1001025-e1001025

2011

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Contribution and Regulation of TRPC Channels in Store-Operated Ca2+ Entry

Current Topics in Membranes, 2013, Vol.71, p.149-179

2013

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Functional Requirement for Orai1 in Store-operated TRPC1-STIM1 Channels

The Journal of biological chemistry, 2008-05, Vol.283 (19), p.12935-12940

2008

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Store-operated Ca2+ entry is remodelled and controls in vitro angiogenesis in endothelial progenitor cells isolated from tumoral patients

PloS one, 2012-09, Vol.7 (9), p.e42541

2012

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Dissection of Calcium Signaling Events in Exocrine Secretion

Neurochemical research, 2011-07, Vol.36 (7), p.1212-1221

Ambudkar, Indu S.

2011

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Sialin (SLC17A5) functions as a nitrate transporter in the plasma membrane

Proceedings of the National Academy of Sciences - PNAS, 2012-08, Vol.109 (33), p.13434-13439

2012

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STIM2 enhances receptor-stimulated Ca²⁺ signaling by promoting recruitment of STIM1 to the endoplasmic reticulum-plasma membrane junctions

Science signaling, 2015-01, Vol.8 (359), p.ra3

2015

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Revealing the fate of cell surface human P-glycoprotein (ABCB1): The lysosomal degradation pathway

Biochimica et biophysica acta, 2015-10, Vol.1853 (10), p.2361-2370

2015

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Lipid Rafts Determine Clustering of STIM1 in Endoplasmic Reticulum-Plasma Membrane Junctions and Regulation of Store-operated Ca2+ Entry (SOCE)

The Journal of biological chemistry, 2008-06, Vol.283 (25), p.17333-17340

2008

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Radiation inhibits salivary gland function by promoting STIM1 cleavage by caspase-3 and loss of SOCE through a TRPM2-dependent pathway

Science signaling, 2017-06, Vol.10 (482)

2017

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Calcium signalling in salivary gland physiology and dysfunction

The Journal of physiology, 2016-06, Vol.594 (11), p.2813-2824

Ambudkar, Indu S.

2016

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Ion channels and transporters in cancer. 6. Vascularizing the tumor: TRP channels as molecular targets

American Journal of Physiology: Cell Physiology, 2012-01, Vol.302 (1), p.C9-C15

2012

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Activation of TRPC1 by STIM1 in ER-PM microdomains involves release of the channel from its scaffold caveolin-1

Proceedings of the National Academy of Sciences - PNAS, 2009-11, Vol.106 (47), p.20087-20092

2009

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Heteromeric TRPV4-C1 channels contribute to store-operated Ca2+ entry in vascular endothelial cells

Cell calcium (Edinburgh), 2011-12, Vol.50 (6), p.502-509

2011

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IP3R deficit underlies loss of salivary fluid secretion in Sjögren's Syndrome

Scientific reports, 2015-09, Vol.5 (1), p.13953-13953, Article 13953

2015

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Polarized but Differential Localization and Recruitment of STIM1, Orai1 and TRPC Channels in Secretory Cells

Traffic (Copenhagen, Denmark), 2011-02, Vol.12 (2), p.232-245

2011

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TRPC1: The link between functionally distinct store-operated calcium channels

Cell calcium (Edinburgh), 2007-08, Vol.42 (2), p.213-223

2007

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STIM-TRP Pathways and Microdomain Organization: Contribution of TRPC1 in Store-Operated Ca2+ Entry: Impact on Ca2+ Signaling and Cell Function

Store-Operated Ca²⁺ Entry (SOCE) Pathways, p.159-188

Volltextzugriff (PDF)

Attenuation of store-operated Ca²⁺ current impairs salivary gland fluid secretion in TRPC1(-/-) mice

Proceedings of the National Academy of Sciences - PNAS, 2007-10, Vol.104 (44), p.17542-17547

2007

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TRPC1, Orai1, and STIM1 in SOCE: Friends in tight spaces

Cell calcium (Edinburgh), 2017-05, Vol.63, p.33-39

2017

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Impairment of TRPC1-STIM1 channel assembly and AQP5 translocation compromise agonist-stimulated fluid secretion in mice lacking caveolin1

Journal of cell science, 2013-01, Vol.126 (Pt 2), p.667-675

2013

Volltextzugriff (PDF)

STIM1 and STIM2 protein deficiency in T lymphocytes underlies development of the exocrine gland autoimmune disease, Sjögren's syndrome

Proceedings of the National Academy of Sciences - PNAS, 2012-09, Vol.109 (36), p.14544-14549

2012

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Trafficking mechanisms and regulation of TRPC channels

Cell calcium (Edinburgh), 2014-08, Vol.56 (2), p.43-50

2014

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The dynamic complexity of the TRPC1 channelosome

Channels (Austin, Tex.), 2011-09, Vol.5 (5), p.424-431

2011

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Ca2+ signaling and regulation of fluid secretion in salivary gland acinar cells

Local Ca²+ entry via Orai1 regulates plasma membrane recruitment of TRPC1 and controls cytosolic Ca²+ signals required for specific cell functions

Contribution and Regulation of TRPC Channels in Store-Operated Ca2+ Entry

Functional Requirement for Orai1 in Store-operated TRPC1-STIM1 Channels

Store-operated Ca2+ entry is remodelled and controls in vitro angiogenesis in endothelial progenitor cells isolated from tumoral patients

Dissection of Calcium Signaling Events in Exocrine Secretion

Sialin (SLC17A5) functions as a nitrate transporter in the plasma membrane

STIM2 enhances receptor-stimulated Ca²⁺ signaling by promoting recruitment of STIM1 to the endoplasmic reticulum-plasma membrane junctions

Revealing the fate of cell surface human P-glycoprotein (ABCB1): The lysosomal degradation pathway

Lipid Rafts Determine Clustering of STIM1 in Endoplasmic Reticulum-Plasma Membrane Junctions and Regulation of Store-operated Ca2+ Entry (SOCE)

Radiation inhibits salivary gland function by promoting STIM1 cleavage by caspase-3 and loss of SOCE through a TRPM2-dependent pathway

Calcium signalling in salivary gland physiology and dysfunction

Ion channels and transporters in cancer. 6. Vascularizing the tumor: TRP channels as molecular targets

Activation of TRPC1 by STIM1 in ER-PM microdomains involves release of the channel from its scaffold caveolin-1

Heteromeric TRPV4-C1 channels contribute to store-operated Ca2+ entry in vascular endothelial cells

IP3R deficit underlies loss of salivary fluid secretion in Sjögren's Syndrome

Polarized but Differential Localization and Recruitment of STIM1, Orai1 and TRPC Channels in Secretory Cells

TRPC1: The link between functionally distinct store-operated calcium channels

STIM-TRP Pathways and Microdomain Organization: Contribution of TRPC1 in Store-Operated Ca2+ Entry: Impact on Ca2+ Signaling and Cell Function

Attenuation of store-operated Ca²⁺ current impairs salivary gland fluid secretion in TRPC1(-/-) mice

TRPC1, Orai1, and STIM1 in SOCE: Friends in tight spaces

Impairment of TRPC1-STIM1 channel assembly and AQP5 translocation compromise agonist-stimulated fluid secretion in mice lacking caveolin1

STIM1 and STIM2 protein deficiency in T lymphocytes underlies development of the exocrine gland autoimmune disease, Sjögren's syndrome

Trafficking mechanisms and regulation of TRPC channels

The dynamic complexity of the TRPC1 channelosome

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