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Sortases: structure, mechanism, and implications for protein engineering

Trends in biochemical sciences (Amsterdam. Regular ed.), 2024-07, Vol.49 (7), p.596-610

2024

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The Src module: an ancient scaffold in the evolution of cytoplasmic tyrosine kinases

Critical reviews in biochemistry and molecular biology, 2018-09, Vol.53 (5), p.535-563

2018

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An Idea to Explore: Engaging High School Students in Structure-Function Studies of Bacterial Sortase Enzymes and Inhibitors -- A Comprehensive Computational Experimental Pipeline

Biochemistry and molecular biology education, 2023-11, Vol.51 (6), p.606-615

2023

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Saturation mutagenesis of a predicted ancestral Syk‐family kinase

Protein science, 2022-10, Vol.31 (10), p.n/a

2022

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A Compact Structure of Cytochrome c Trapped in a Lysine-Ligated State: Loop Refolding and Functional Implications of a Conformational Switch

Journal of the American Chemical Society, 2015-07, Vol.137 (26), p.8435-8449

2015

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Intracellular Delivery of Peptidyl Ligands by Reversible Cyclization: Discovery of a PDZ Domain Inhibitor that Rescues CFTR Activity

Angewandte Chemie International Edition, 2015-05, Vol.54 (20), p.5874-5878

International ed. in English, 2015

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A Phosphosite within the SH2 Domain of Lck Regulates Its Activation by CD45

Molecular cell, 2017-08, Vol.67 (3), p.498-511.e6

2017

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Chemically modified peptide scaffolds target the CFTR-associated ligand PDZ domain

PloS one, 2014-08, Vol.9 (8), p.e103650

2014

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MotifAnalyzer‐PDZ: A computational program to investigate the evolution of PDZ‐binding target specificity

Protein science, 2019-12, Vol.28 (12), p.2127-2143

2019

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Specificity in PDZ-peptide interaction networks: Computational analysis and review

Journal of structural biology. X, 2020-01, Vol.4, p.100022-100022, Article 100022

2020

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Domain Analysis and Motif Matcher (DAMM): A Program to Predict Selectivity Determinants in Monosiga brevicollis PDZ Domains Using Human PDZ Data

Molecules (Basel, Switzerland), 2021-10, Vol.26 (19), p.6034

2021

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Sequence variation in the β7–β8 loop of bacterial class A sortase enzymes alters substrate selectivity

The Journal of biological chemistry, 2021-08, Vol.297 (2), p.100981-100981, Article 100981

2021

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Structural and biochemical analyses of selectivity determinants in chimeric Streptococcus Class A sortase enzymes

Protein science, 2022-03, Vol.31 (3), p.701-715

2022

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Structures of Streptococcus pyogenes class A sortase in complex with substrate and product mimics provide key details of target recognition

The Journal of biological chemistry, 2022-10, Vol.298 (10), p.102446-102446, Article 102446

2022

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Stereochemical Preferences Modulate Affinity and Selectivity among Five PDZ Domains that Bind CFTR: Comparative Structural and Sequence Analyses

Structure (London), 2014-01, Vol.22 (1), p.82-93

2014

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Additive energetic contributions of multiple peptide positions determine the relative promiscuity of viral and human sequences for PDZ domain targets

Protein science, 2023-04, Vol.32 (4), p.e4611-n/a

2023

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Abstract 2589: Probing alternative substrate binding and cleavage of class A sortases

The Journal of biological chemistry, 2023, Vol.299 (3), p.103675, Article 103675

2023

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Abstract 2584: Investigating the effects of non-motif residues on the binding affinity of CFTR and HPV16 to human PDZ domains

The Journal of biological chemistry, 2023, Vol.299 (3), p.104181, Article 104181

2023

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Phosphorylation control of the ubiquitin ligase Cbl is conserved in choanoflagellates

Protein science, 2018-05, Vol.27 (5), p.923-932

2018

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Structural characterization and computational analysis of PDZ domains in Monosiga brevicollis

Protein science, 2020-11, Vol.29 (11), p.2226-2244

2020

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Stereochemical determinants of C-terminal specificity in PDZ peptide-binding domains: a novel contribution of the carboxylate-binding loop

The Journal of biological chemistry, 2013-02, Vol.288 (7), p.5114-5126

2013

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Correction to “A Compact Structure of Cytochrome c Trapped in a Lysine-Ligated State: Loop Refolding and Functional Implications of a Conformational Switch”

Journal of the American Chemical Society, 2018-03, Vol.140 (12), p.4466-4466

2018

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A unique binding mode of P1' Leu-containing target sequences for Streptococcus pyogenes sortase A results in alternative cleavage

RSC chemical biology, 2024-01, Vol.5 (1), p.30-40

2024

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Abstract 2568: Structural and binding studies of the beta4-beta5 loop in Streptococcus pyogenes Sortase A

The Journal of biological chemistry, 2023, Vol.299 (3), p.104180, Article 104180

2023

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Intracellular Delivery of Peptidyl Ligands by Reversible Cyclization: Discovery of a PDZ Domain Inhibitor that Rescues CFTR Activity

Angewandte Chemie, 2015-05, Vol.127 (20), p.5972-5976

2015

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Sortases: structure, mechanism, and implications for protein engineering

The Src module: an ancient scaffold in the evolution of cytoplasmic tyrosine kinases

An Idea to Explore: Engaging High School Students in Structure-Function Studies of Bacterial Sortase Enzymes and Inhibitors -- A Comprehensive Computational Experimental Pipeline

Saturation mutagenesis of a predicted ancestral Syk‐family kinase

A Compact Structure of Cytochrome c Trapped in a Lysine-Ligated State: Loop Refolding and Functional Implications of a Conformational Switch

Intracellular Delivery of Peptidyl Ligands by Reversible Cyclization: Discovery of a PDZ Domain Inhibitor that Rescues CFTR Activity

A Phosphosite within the SH2 Domain of Lck Regulates Its Activation by CD45

Chemically modified peptide scaffolds target the CFTR-associated ligand PDZ domain

MotifAnalyzer‐PDZ: A computational program to investigate the evolution of PDZ‐binding target specificity

Specificity in PDZ-peptide interaction networks: Computational analysis and review

Domain Analysis and Motif Matcher (DAMM): A Program to Predict Selectivity Determinants in Monosiga brevicollis PDZ Domains Using Human PDZ Data

Sequence variation in the β7–β8 loop of bacterial class A sortase enzymes alters substrate selectivity

Structural and biochemical analyses of selectivity determinants in chimeric Streptococcus Class A sortase enzymes

Structures of Streptococcus pyogenes class A sortase in complex with substrate and product mimics provide key details of target recognition

Stereochemical Preferences Modulate Affinity and Selectivity among Five PDZ Domains that Bind CFTR: Comparative Structural and Sequence Analyses

Additive energetic contributions of multiple peptide positions determine the relative promiscuity of viral and human sequences for PDZ domain targets

Abstract 2589: Probing alternative substrate binding and cleavage of class A sortases

Abstract 2584: Investigating the effects of non-motif residues on the binding affinity of CFTR and HPV16 to human PDZ domains

Phosphorylation control of the ubiquitin ligase Cbl is conserved in choanoflagellates

Structural characterization and computational analysis of PDZ domains in Monosiga brevicollis

Stereochemical determinants of C-terminal specificity in PDZ peptide-binding domains: a novel contribution of the carboxylate-binding loop

Correction to “A Compact Structure of Cytochrome c Trapped in a Lysine-Ligated State: Loop Refolding and Functional Implications of a Conformational Switch”

A unique binding mode of P1' Leu-containing target sequences for Streptococcus pyogenes sortase A results in alternative cleavage

Abstract 2568: Structural and binding studies of the beta4-beta5 loop in Streptococcus pyogenes Sortase A

Intracellular Delivery of Peptidyl Ligands by Reversible Cyclization: Discovery of a PDZ Domain Inhibitor that Rescues CFTR Activity

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