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Influence of Several Compounds and Drugs on the Renal Uptake of Radiolabeled Affibody Molecules

Molecules (Basel, Switzerland), 2020-06, Vol.25 (11), p.2673

2020

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Evaluation of an antibody-PNA conjugate as a clearing agent for antibody-based PNA-mediated radionuclide pretargeting

Scientific reports, 2020-11, Vol.10 (1), p.20777, Article 20777

2020

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Hematological and renal toxicity in mice after three cycles of high activity [177Lu]Lu-PSMA-617 with or without human α1-microglobulin

Scientific reports, 2024-05, Vol.14 (1), p.10787-12, Article 10787

2024

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On the prevention of kidney uptake of radiolabeled DARPins

EJNMMI research, 2020-02, Vol.10 (1), p.7-7, Article 7

2020

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Feasibility of Imaging EpCAM Expression in Ovarian Cancer Using Radiolabeled DARPin Ec1

International journal of molecular sciences, 2020-05, Vol.21 (9), p.3310

2020

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PSA-Targeted Alpha-, Beta-, and Positron-Emitting Immunotheranostics in Murine Prostate Cancer Models and Nonhuman Primates

Clinical cancer research, 2021-04, Vol.27 (7), p.2050-2060

2021

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Feasibility of Affibody Molecule-Based PNA-Mediated Radionuclide Pretargeting of Malignant Tumors

Theranostics, 2016, Vol.6 (1), p.93-103

2016

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Radiolabeled probes targeting tyrosine-kinase receptors for personalized medicine

Current pharmaceutical design, 2014, Vol.20 (14), p.2275-2292

2014

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Incorporation of a Hydrophilic Spacer Reduces Hepatic Uptake of HER2-Targeting Affibody-DM1 Drug Conjugates

Cancers, 2019-08, Vol.11 (8), p.1168

2019

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A Conjugation Strategy to Modulate Antigen Binding and FcRn Interaction Leads to Improved Tumor Targeting and Radioimmunotherapy Efficacy with an Antibody Targeting Prostate-Specific Antigen

Cancers, 2021-07, Vol.13 (14), p.3469

2021

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The Influence of Domain Permutations of an Albumin-Binding Domain-Fused HER2-Targeting Affibody-Based Drug Conjugate on Tumor Cell Proliferation and Therapy Efficacy

Pharmaceutics, 2021-11, Vol.13 (11), p.1974

2021

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Hematological Toxicity in Mice after High Activity Injections of 177Lu-PSMA-617

Pharmaceutics, 2022-03, Vol.14 (4), p.731

2022

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HER2-Specific Pseudomonas Exotoxin A PE25 Based Fusions: Influence of Targeting Domain on Target Binding, Toxicity, and In Vivo Biodistribution

Pharmaceutics, 2020-04, Vol.12 (4), p.391

2020

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Evaluating the Therapeutic Efficacy of Mono- and Bivalent Affibody-Based Fusion Proteins Targeting HER3 in a Pancreatic Cancer Xenograft Model

Pharmaceutics, 2020, Vol.12 (6), p.551

2020

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Influence of Molecular Design on the Targeting Properties of ABD-Fused Mono- and Bi-Valent Anti-HER3 Affibody Therapeutic Constructs

Cells (Basel, Switzerland), 2018-10, Vol.7 (10), p.164

2018

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177Lu-PSMA-617 Therapy in Mice, with or without the Antioxidant α1-Microglobulin (A1M), Including Kidney Damage Assessment Using 99mTc-MAG3 Imaging

Biomolecules (Basel, Switzerland), 2021-02, Vol.11 (2), p.263

2021

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Pretargeted Imaging and Therapy

Journal of Nuclear Medicine, 2017-10, Vol.58 (10), p.1553-1559

2017

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Imaging of HER3-expressing xenografts in mice using a 99mTc(CO)3-HEHEHE-ZHER3:08699 affibody molecule

European journal of nuclear medicine and molecular imaging, 2014-07, Vol.41 (7), p.1450-1459

2014

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The effect of mini-PEG-based spacer length on binding and pharmacokinetic properties of a 68Ga-labeled NOTA-conjugated antagonistic analog of bombesin

Molecules (Basel, Switzerland), 2014-07, Vol.19 (7), p.10455-10472

2014

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Hematological and renal toxicity in mice after three cycles of high activity 177LuLu-PSMA-617 with or without human α1-microglobulin

Scientific reports, 2024-05, Vol.14 (1), p.10787

2024

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Affibody-derived drug conjugates: Potent cytotoxic molecules for treatment of HER2 over-expressing tumors

Journal of controlled release, 2018-10, Vol.288, p.84-95

2018

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Radionuclide Tumor Targeting Using ADAPT Scaffold Proteins: Aspects of Label Positioning and Residualizing Properties of the Label

Journal of Nuclear Medicine, 2018-01, Vol.59 (1), p.93-99

2018

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Radionuclide therapy using ABD-fused ADAPT scaffold protein: Proof of Principle

Biomaterials, 2021-01, Vol.266, p.120381-120381, Article 120381

2021

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Radionuclide Therapy of HER2-Expressing Human Xenografts Using Affibody-Based Peptide Nucleic Acid-Mediated Pretargeting: In Vivo Proof of Principle

Journal of Nuclear Medicine, 2018-07, Vol.59 (7), p.1092-1098

2018

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Site-specific conjugation of recognition tags to trastuzumab for peptide nucleic acid-mediated radionuclide HER2 pretargeting

Biomaterials, 2019-05, Vol.203, p.73-85

2019

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Influence of Several Compounds and Drugs on the Renal Uptake of Radiolabeled Affibody Molecules

Evaluation of an antibody-PNA conjugate as a clearing agent for antibody-based PNA-mediated radionuclide pretargeting

Hematological and renal toxicity in mice after three cycles of high activity [177Lu]Lu-PSMA-617 with or without human α1-microglobulin

On the prevention of kidney uptake of radiolabeled DARPins

Feasibility of Imaging EpCAM Expression in Ovarian Cancer Using Radiolabeled DARPin Ec1

PSA-Targeted Alpha-, Beta-, and Positron-Emitting Immunotheranostics in Murine Prostate Cancer Models and Nonhuman Primates

Feasibility of Affibody Molecule-Based PNA-Mediated Radionuclide Pretargeting of Malignant Tumors

Radiolabeled probes targeting tyrosine-kinase receptors for personalized medicine

Incorporation of a Hydrophilic Spacer Reduces Hepatic Uptake of HER2-Targeting Affibody-DM1 Drug Conjugates

A Conjugation Strategy to Modulate Antigen Binding and FcRn Interaction Leads to Improved Tumor Targeting and Radioimmunotherapy Efficacy with an Antibody Targeting Prostate-Specific Antigen

The Influence of Domain Permutations of an Albumin-Binding Domain-Fused HER2-Targeting Affibody-Based Drug Conjugate on Tumor Cell Proliferation and Therapy Efficacy

Hematological Toxicity in Mice after High Activity Injections of 177Lu-PSMA-617

HER2-Specific Pseudomonas Exotoxin A PE25 Based Fusions: Influence of Targeting Domain on Target Binding, Toxicity, and In Vivo Biodistribution

Evaluating the Therapeutic Efficacy of Mono- and Bivalent Affibody-Based Fusion Proteins Targeting HER3 in a Pancreatic Cancer Xenograft Model

Influence of Molecular Design on the Targeting Properties of ABD-Fused Mono- and Bi-Valent Anti-HER3 Affibody Therapeutic Constructs

177Lu-PSMA-617 Therapy in Mice, with or without the Antioxidant α1-Microglobulin (A1M), Including Kidney Damage Assessment Using 99mTc-MAG3 Imaging

Pretargeted Imaging and Therapy

Imaging of HER3-expressing xenografts in mice using a 99mTc(CO)3-HEHEHE-ZHER3:08699 affibody molecule

The effect of mini-PEG-based spacer length on binding and pharmacokinetic properties of a 68Ga-labeled NOTA-conjugated antagonistic analog of bombesin

Hematological and renal toxicity in mice after three cycles of high activity 177LuLu-PSMA-617 with or without human α1-microglobulin

Affibody-derived drug conjugates: Potent cytotoxic molecules for treatment of HER2 over-expressing tumors

Radionuclide Tumor Targeting Using ADAPT Scaffold Proteins: Aspects of Label Positioning and Residualizing Properties of the Label

Radionuclide therapy using ABD-fused ADAPT scaffold protein: Proof of Principle

Radionuclide Therapy of HER2-Expressing Human Xenografts Using Affibody-Based Peptide Nucleic Acid-Mediated Pretargeting: In Vivo Proof of Principle

Site-specific conjugation of recognition tags to trastuzumab for peptide nucleic acid-mediated radionuclide HER2 pretargeting

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