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Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation

Nature communications, 2019-04, Vol.10 (1), p.1689-1689, Article 1689

2019

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Non-transcriptional Priming and Deubiquitination Regulate NLRP3 Inflammasome Activation

The Journal of biological chemistry, 2012-10, Vol.287 (43), p.36617-36622

2012

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AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

Nature, 2009-03, Vol.458 (7237), p.509-513

2009

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The NLRP6 Inflammasome Recognizes Lipoteichoic Acid and Regulates Gram-Positive Pathogen Infection

Cell, 2018-11, Vol.175 (6), p.1651-1664.e14

2018

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Cutting edge: TLR signaling licenses IRAK1 for rapid activation of the NLRP3 inflammasome

The Journal of immunology (1950), 2013-10, Vol.191 (8), p.3995-3999

2013

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Morphology of Mitochondria in Syncytial Annelid Female Germ-Line Cyst Visualized by Serial Block-Face SEM

International journal of cell biology, 2020, Vol.2020 (2020), p.1-15

2020

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Involvement of the AIM2, NLRC4, and NLRP3 Inflammasomes in Caspase-1 Activation by Listeria monocytogenes

Journal of clinical immunology, 2010-09, Vol.30 (5), p.693-702

2010

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Mutant BRAF and MEK Inhibitors Regulate the Tumor Immune Microenvironment via Pyroptosis

Cancer discovery, 2020-02, Vol.10 (2), p.254-269

2020

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Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3

Nature communications, 2015-06, Vol.6 (1), p.7515-7515, Article 7515

2015

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Anti-inflammatory Compounds Parthenolide and Bay 11-7082 Are Direct Inhibitors of the Inflammasome

The Journal of biological chemistry, 2010-03, Vol.285 (13), p.9792-9802

2010

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Inflammasome priming by lipopolysaccharide is dependent upon ERK signaling and proteasome function

The Journal of immunology (1950), 2014-04, Vol.192 (8), p.3881-3888

2014

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Chloride sensing by WNK1 regulates NLRP3 inflammasome activation and pyroptosis

Nature communications, 2021-07, Vol.12 (1), p.4546-4546, Article 4546

2021

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The AIM2 inflammasome is critical for innate immunity to Francisella tularensis

Nature immunology, 2010-05, Vol.11 (5), p.385-393

2010

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SUMO-mediated regulation of NLRP3 modulates inflammasome activity

Nature communications, 2018-08, Vol.9 (1), p.3001-14, Article 3001

2018

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The mitochondrial antiviral protein MAVS associates with NLRP3 and regulates its inflammasome activity

The Journal of immunology (1950), 2013-10, Vol.191 (8), p.4358-4366

2013

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The Yersinia pestis Effector YopM Inhibits Pyrin Inflammasome Activation

PLoS pathogens, 2016-12, Vol.12 (12), p.e1006035-e1006035

2016

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Raptinal Induces Gasdermin E-Dependent Pyroptosis in Naïve and Therapy-Resistant Melanoma

Molecular cancer research, 2022-12, Vol.20 (12), p.1811-1821

2022

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Critical roles of ASC inflammasomes in caspase-1 activation and host innate resistance to Streptococcus pneumoniae infection

The Journal of immunology (1950), 2011-11, Vol.187 (9), p.4890-4899

2011

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Gasdermins in Apoptosis: New players in an Old Game

The Yale journal of biology & medicine, 2019-12, Vol.92 (4), p.603-617

2019

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Pyrin Activates the ASC Pyroptosome in Response to Engagement by Autoinflammatory PSTPIP1 Mutants

Molecular cell, 2007-10, Vol.28 (2), p.214-227

2007

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Inactivation of Omi/HtrA2 protease leads to the deregulation of mitochondrial Mulan E3 ubiquitin ligase and increased mitophagy

Biochimica et biophysica acta, 2014-07, Vol.1843 (7), p.1295-1307

2014

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Sensing Cytoplasmic Danger Signals by the Inflammasome

Journal of clinical immunology, 2010-07, Vol.30 (4), p.512-519

Alnemri, Emad S

2010

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Gasdermins: novel mitochondrial pore-forming proteins

Molecular & cellular oncology, 2019-01, Vol.6 (5), p.e1621501-e1621501

2019

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A novel role for the mitochondrial HTRA2/OMI protease in aging

Autophagy, 2013-03, Vol.9 (3), p.420-421

2013

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Caspase-2 Induces Apoptosis by Releasing Proapoptotic Proteins from Mitochondria

The Journal of biological chemistry, 2002-04, Vol.277 (16), p.13430-13437

2002

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Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation

Non-transcriptional Priming and Deubiquitination Regulate NLRP3 Inflammasome Activation

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

The NLRP6 Inflammasome Recognizes Lipoteichoic Acid and Regulates Gram-Positive Pathogen Infection

Cutting edge: TLR signaling licenses IRAK1 for rapid activation of the NLRP3 inflammasome

Morphology of Mitochondria in Syncytial Annelid Female Germ-Line Cyst Visualized by Serial Block-Face SEM

Involvement of the AIM2, NLRC4, and NLRP3 Inflammasomes in Caspase-1 Activation by Listeria monocytogenes

Mutant BRAF and MEK Inhibitors Regulate the Tumor Immune Microenvironment via Pyroptosis

Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3

Anti-inflammatory Compounds Parthenolide and Bay 11-7082 Are Direct Inhibitors of the Inflammasome

Inflammasome priming by lipopolysaccharide is dependent upon ERK signaling and proteasome function

Chloride sensing by WNK1 regulates NLRP3 inflammasome activation and pyroptosis

The AIM2 inflammasome is critical for innate immunity to Francisella tularensis

SUMO-mediated regulation of NLRP3 modulates inflammasome activity

The mitochondrial antiviral protein MAVS associates with NLRP3 and regulates its inflammasome activity

The Yersinia pestis Effector YopM Inhibits Pyrin Inflammasome Activation

Raptinal Induces Gasdermin E-Dependent Pyroptosis in Naïve and Therapy-Resistant Melanoma

Critical roles of ASC inflammasomes in caspase-1 activation and host innate resistance to Streptococcus pneumoniae infection

Gasdermins in Apoptosis: New players in an Old Game

Pyrin Activates the ASC Pyroptosome in Response to Engagement by Autoinflammatory PSTPIP1 Mutants

Inactivation of Omi/HtrA2 protease leads to the deregulation of mitochondrial Mulan E3 ubiquitin ligase and increased mitophagy

Sensing Cytoplasmic Danger Signals by the Inflammasome

Gasdermins: novel mitochondrial pore-forming proteins

A novel role for the mitochondrial HTRA2/OMI protease in aging

Caspase-2 Induces Apoptosis by Releasing Proapoptotic Proteins from Mitochondria

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