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Physiologically‐based pharmacokinetic modelling to predict intragastric rifabutin concentrations in the treatment of Helicobacter pylori infection

Alimentary pharmacology & therapeutics, 2023-07, Vol.58 (2), p.159-167

2023

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S1451 Pitfalls of Physician-Directed Treatment of H. pylori Infection: Results From Two Phase 3 Clinical Trials and Real-World Prescribing Data

The American journal of gastroenterology, 2021-10, Vol.116 (1), p.S665-S665

2021

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Eluxadoline Benefits Patients With Irritable Bowel Syndrome With Diarrhea in a Phase 2 Study

Gastroenterology (New York, N.Y. 1943), 2013-08, Vol.145 (2), p.329-338.e1

2013

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Pitfalls of Physician-Directed Treatment of Helicobacter pylori: Results from Two Phase 3 Clinical Trials and Real-World Prescribing Data

Digestive diseases and sciences, 2022-09, Vol.67 (9), p.4382-4386

2022

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Development of a new travellers’ diarrhoea clinical severity classification and its utility in confirming rifamycin-SV efficacy

Journal of travel medicine, 2023-10, Vol.30 (6)

2023

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Disproportionality analysis using empirical Bayes data mining: a tool for the evaluation of drug interactions in the post-marketing setting

Pharmacoepidemiology and drug safety, 2003-09, Vol.12 (6), p.517-521

2003

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S1417 RHB-105 Q8H Rifabutin Dosing Provides Favorable Exposure for Helicobacter pylori Eradication

The American journal of gastroenterology, 2021-10, Vol.116 (1), p.S650-S650

2021

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Molecular clinical safety intelligence: a system for bridging clinically focused safety knowledge to early-stage drug discovery – the GSK experience

Drug discovery today, 2011-08, Vol.16 (15), p.646-653

2011

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Association of asthma therapy and churg-strauss syndrome: An analysis of postmarketing surveillance data

Clinical therapeutics, 2004-07, Vol.26 (7), p.1092-1104

2004

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Efficacy and Safety of Naloxegol in Patients with Chronic Non-Cancer Pain Who Experience Opioid-Induced Constipation: A Pooled Analysis of Two Global, Randomized Controlled Studies

Journal of pain research, 2023-09, Vol.16, p.2943-2953

2023

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Innovations for the future of pharmacovigilance

Drug safety, 2007-01, Vol.30 (7), p.631-633

ALMENOFF, June S

2007

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Comparative performance of two quantitative safety signalling methods : Implications for use in a pharmacovigilance department

Drug safety, 2006-01, Vol.29 (10), p.875-887

2006

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Sa1381 PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODELING CONFIRMS RIFABUTIN, AMOXICILLIN, AND OMEPRAZOLE BIOEQUIVALENCE BETWEEN Q8H AND TID DOSING FOR LOW-DOSE RIFABUTIN TRIPLE THERAPY (RHB-105) FOR THE ERADICATION OF HELICOBACTER PYLORI IN ADULT PATIENTS

Gastroenterology (New York, N.Y. 1943), 2023-05, Vol.164 (6), p.S-380-S-381

2023

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Tu1077: PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODEL TO ESTIMATE INTRAGASTRIC RIFABUTIN CONCENTRATIONS FOLLOWING RIFABUTIN 50 MG Q8H (RHB-105) OR 150 MG QD: MORE FAVORABLE EXPOSURE FOR HELICOBACTER PYLORI ERADICATON WITH Q8H DOSING

Gastroenterology (New York, N.Y. 1943), 2022-05, Vol.162 (7), p.S-873-S-873

2022

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Tu1078: LOW-DOSE RIFABUTIN TRIPLE THERAPY (RHB-105) MAINTAINS HIGH HELICOBACTER PYLORI ERADICATION RATES AND SHOWS FAVORABLE SAFETY AND EFFICACY IN SUBJECTS WITH DIABETES MELLITUS

Gastroenterology (New York, N.Y. 1943), 2022-05, Vol.162 (7), p.S-873-S-874

2022

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Helicobacter pylori eradication by low‐dose rifabutin triple therapy (RHB‐105) is unaffected by high body mass index

GastroHep, 2021-12, Vol.3 (7), p.426-434

2021

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Regulation of Cell Signaling by the Cytoplasmic Domains of the Heat-Stable Enterotoxin Receptor: Identification of Autoinhibitory and Activating Motifs

Proceedings of the National Academy of Sciences - PNAS, 1995-05, Vol.92 (11), p.5169-5173

1995

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Ligand‐based histochemical localization and capture of cells expressing heat‐stable enterotoxin receptors

Molecular microbiology, 1993-05, Vol.8 (5), p.865-873

1993

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Biogenesis, Cellular Localization, and Functional Activation of the Heat-Stable Enterotoxin Receptor (Guanylyl Cyclase C)

Biochemistry (Easton), 1996-08, Vol.35 (33), p.10680-10686

1996

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Empirical Bayesian data mining for discovering patterns in post-marketing drug safety

Conference on Knowledge Discovery in Data: Proceedings of the ninth ACM SIGKDD international conference on Knowledge discovery and data mining; 24-27 Aug. 2003, 2003, p.359-368

2003

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Online Signal Management: A Systems-Based Approach That Delivers New Analytical Capabilities and Operational Efficiency to the Practice of Pharmacovigilance

Drug information journal, 2007-11, Vol.41 (6), p.779-789

2007

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Molecular Cloning and Characterization of SCaMPER, a Sphingolipid Ca2+ Release-Mediating Protein from Endoplasmic Reticulum

Proceedings of the National Academy of Sciences - PNAS, 1996-03, Vol.93 (5), p.1993-1996

1996

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Letter to the Editor-Re: Almenoff et al., 'Disproportionality analysis using empirical Bayes data mining: a tool for the evaluation of drug interactions in the post-marketing setting', (PDS, 2003; 12(6); 517-521)

Pharmacoepidemiology and drug safety, 2004-02, Vol.13 (2), p.111-111

2004

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Induction of heat-stable enterotoxin receptor activity by a human Alu repeat

The Journal of biological chemistry, 1994-06, Vol.269 (24), p.16610-16617

1994

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Molecular cloning and characterization of SCaMPER, a sphingolipid Ca2positive release-mediating protein from endoplasmic reticulum

Proceedings of the National Academy of Sciences - PNAS, 1996-03, Vol.93 (5), p.1993

1996

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Physiologically‐based pharmacokinetic modelling to predict intragastric rifabutin concentrations in the treatment of Helicobacter pylori infection

S1451 Pitfalls of Physician-Directed Treatment of H. pylori Infection: Results From Two Phase 3 Clinical Trials and Real-World Prescribing Data

Eluxadoline Benefits Patients With Irritable Bowel Syndrome With Diarrhea in a Phase 2 Study

Pitfalls of Physician-Directed Treatment of Helicobacter pylori: Results from Two Phase 3 Clinical Trials and Real-World Prescribing Data

Development of a new travellers’ diarrhoea clinical severity classification and its utility in confirming rifamycin-SV efficacy

Disproportionality analysis using empirical Bayes data mining: a tool for the evaluation of drug interactions in the post-marketing setting

S1417 RHB-105 Q8H Rifabutin Dosing Provides Favorable Exposure for Helicobacter pylori Eradication

Molecular clinical safety intelligence: a system for bridging clinically focused safety knowledge to early-stage drug discovery – the GSK experience

Association of asthma therapy and churg-strauss syndrome: An analysis of postmarketing surveillance data

Efficacy and Safety of Naloxegol in Patients with Chronic Non-Cancer Pain Who Experience Opioid-Induced Constipation: A Pooled Analysis of Two Global, Randomized Controlled Studies

Innovations for the future of pharmacovigilance

Comparative performance of two quantitative safety signalling methods : Implications for use in a pharmacovigilance department

Sa1381 PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODELING CONFIRMS RIFABUTIN, AMOXICILLIN, AND OMEPRAZOLE BIOEQUIVALENCE BETWEEN Q8H AND TID DOSING FOR LOW-DOSE RIFABUTIN TRIPLE THERAPY (RHB-105) FOR THE ERADICATION OF HELICOBACTER PYLORI IN ADULT PATIENTS

Tu1077: PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODEL TO ESTIMATE INTRAGASTRIC RIFABUTIN CONCENTRATIONS FOLLOWING RIFABUTIN 50 MG Q8H (RHB-105) OR 150 MG QD: MORE FAVORABLE EXPOSURE FOR HELICOBACTER PYLORI ERADICATON WITH Q8H DOSING

Tu1078: LOW-DOSE RIFABUTIN TRIPLE THERAPY (RHB-105) MAINTAINS HIGH HELICOBACTER PYLORI ERADICATION RATES AND SHOWS FAVORABLE SAFETY AND EFFICACY IN SUBJECTS WITH DIABETES MELLITUS

Helicobacter pylori eradication by low‐dose rifabutin triple therapy (RHB‐105) is unaffected by high body mass index

Regulation of Cell Signaling by the Cytoplasmic Domains of the Heat-Stable Enterotoxin Receptor: Identification of Autoinhibitory and Activating Motifs

Ligand‐based histochemical localization and capture of cells expressing heat‐stable enterotoxin receptors

Biogenesis, Cellular Localization, and Functional Activation of the Heat-Stable Enterotoxin Receptor (Guanylyl Cyclase C)

Empirical Bayesian data mining for discovering patterns in post-marketing drug safety

Online Signal Management: A Systems-Based Approach That Delivers New Analytical Capabilities and Operational Efficiency to the Practice of Pharmacovigilance

Molecular Cloning and Characterization of SCaMPER, a Sphingolipid Ca2+ Release-Mediating Protein from Endoplasmic Reticulum

Letter to the Editor-Re: Almenoff et al., 'Disproportionality analysis using empirical Bayes data mining: a tool for the evaluation of drug interactions in the post-marketing setting', (PDS, 2003; 12(6); 517-521)

Induction of heat-stable enterotoxin receptor activity by a human Alu repeat

Molecular cloning and characterization of SCaMPER, a sphingolipid Ca2positive release-mediating protein from endoplasmic reticulum

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