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A selective sphingosine kinase 1 inhibitor integrates multiple molecular therapeutic targets in human leukemia

Blood, 2008-08, Vol.112 (4), p.1382-1391

2008

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Targeting Sphingosine Kinase 1 Inhibits Akt Signaling, Induces Apoptosis, and Suppresses Growth of Human Glioblastoma Cells and Xenografts

Cancer research (Chicago, Ill.), 2009-09, Vol.69 (17), p.6915-6923

2009

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The multikinase inhibitor sorafenib potentiates TRAIL lethality in human leukemia cells in association with mcl-1 and cFLIPL down-regulation

Cancer research (Chicago, Ill.), 2007-10, Vol.67 (19), p.9490-9500

2007

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Periostin in intrahepatic cholangiocarcinoma: Pathobiological insights and clinical implications

Experimental and molecular pathology, 2014-12, Vol.97 (3), p.515-524

2014

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An Integrated Transcriptomic Approach to Identify Molecular Markers of Calcineurin Inhibitor Nephrotoxicity in Pediatric Kidney Transplant Recipients

International journal of molecular sciences, 2021-05, Vol.22 (11), p.5414

2021

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Simultaneous activation of the intrinsic and extrinsic pathways by histone deacetylase (HDAC) inhibitors and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) synergistically induces mitochondrial damage and apoptosis in human leukemia cells

Molecular cancer therapeutics, 2003-12, Vol.2 (12), p.1273-1284

2003

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Interruption of the Ras/MEK/ERK signaling cascade enhances Chk1 inhibitor–induced DNA damage in vitro and in vivo in human multiple myeloma cells

Blood, 2008-09, Vol.112 (6), p.2439-2449

2008

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Role of histone deacetylase inhibitor-induced reactive oxygen species and DNA damage in LAQ-824/fludarabine antileukemic interactions

Molecular cancer therapeutics, 2008-10, Vol.7 (10), p.3285-3297

2008

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Cytokinetically quiescent (G0/G1) human multiple myeloma cells are susceptible to simultaneous inhibition of Chk1 and MEK1/2

Blood, 2011-11, Vol.118 (19), p.5189-5200

2011

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Su1804 Macrophage Phenotypes in Humans With NAFLD

Gastroenterology (New York, N.Y. 1943), 2015-04, Vol.148 (4), p.S-1055-S-1055

2015

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The utility of ETV1, ETV4 and ETV5 RNA in‐situ hybridization in the diagnosis of CIC–DUX sarcomas

Histopathology, 2017-03, Vol.70 (4), p.657-663

2017

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Analytical Validation and Clinical Utilization of the Oncomine Comprehensive Assay Plus Panel for Comprehensive Genomic Profiling in Solid Tumors

Journal of Molecular Pathology, 2023-06, Vol.4 (2), p.109-127

2023

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Intrahepatic Cholangiocarcinoma Progression: Prognostic Factors and Basic Mechanisms

Clinical gastroenterology and hepatology, 2009-11, Vol.7 (11), p.S68-S78

2009

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The Sensitivity and Specificity of Touch Preparation for Rapid Diagnosis of Invasive Fungal Sinusitis: A Pilot Study

Ear, nose, & throat journal, 2021-01, Vol.100 (1), p.55-59

2021

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Histone Deacetylase Inhibitors Activate NF-κB in Human Leukemia Cells through an ATM/NEMO-related Pathway

The Journal of biological chemistry, 2010-03, Vol.285 (13), p.10064-10077

2010

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The Histone Deacetylase Inhibitor LAQ824 Induces Human Leukemia Cell Death through a Process Involving XIAP Down-Regulation, Oxidative Injury, and the Acid Sphingomyelinase-Dependent Generation of Ceramide

Molecular pharmacology, 2006-01, Vol.69 (1), p.216-225

2006

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Histone deacetylase inhibitors activate NF-κB in human leukemia cells through an ATM/NEMO-related pathway

The Journal of biological chemistry, 2016-08, Vol.291 (34), p.17535-17535

2016

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Quality control material for the detection of somatic mutations in fixed clinical specimens by next-generation sequencing

Diagnostic pathology, 2015-09, Vol.10 (1), p.169-169, Article 169

2015

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Flavopiridol and Histone Deacetylase Inhibitors Promote Mitochondrial Injury and Cell Death in Human Leukemia Cells That Overexpress Bcl-2

Molecular pharmacology, 2006-01, Vol.69 (1), p.288-298

2006

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Mechanism and functional role of XIAP and Mcl-1 down-regulation in flavopiridol/vorinostat antileukemic interactions

Molecular cancer therapeutics, 2007-02, Vol.6 (2), p.692-702

2007

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Disruption of Src function potentiates Chk1-inhibitor–induced apoptosis in human multiple myeloma cells in vitro and in vivo

Blood, 2011-02, Vol.117 (6), p.1947-1957

2011

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The Sensitivity and Specificity of Touch Preparation for Rapid Diagnosis of Invasive Fungal Sinusitis: A Pilot Study

Ear, nose, & throat journal, 2018-01, Vol.97 (1-2), p.E32-E36

2018

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Preclinical assessment of simultaneous targeting of epidermal growth factor receptor (ErbB1) and ErbB2 as a strategy for cholangiocarcinoma therapy

Hepatology (Baltimore, Md.), 2010-09, Vol.52 (3), p.975-986

2010

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Induction of apoptosis in human leukemia cells by the tyrosine kinase inhibitor adaphostin proceeds through a RAF-1 MEK ERK- and AKT-dependent process

Oncogene, 2004-02, Vol.23 (7), p.1364-1376

2004

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Potentiation of the lethality of the histone deacetylase inhibitor LAQ824 by the cyclin-dependent kinase inhibitor roscovitine in human leukemia cells

Molecular cancer therapeutics, 2005-11, Vol.4 (11), p.1772-1785

2005

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A selective sphingosine kinase 1 inhibitor integrates multiple molecular therapeutic targets in human leukemia

Targeting Sphingosine Kinase 1 Inhibits Akt Signaling, Induces Apoptosis, and Suppresses Growth of Human Glioblastoma Cells and Xenografts

The multikinase inhibitor sorafenib potentiates TRAIL lethality in human leukemia cells in association with mcl-1 and cFLIPL down-regulation

Periostin in intrahepatic cholangiocarcinoma: Pathobiological insights and clinical implications

An Integrated Transcriptomic Approach to Identify Molecular Markers of Calcineurin Inhibitor Nephrotoxicity in Pediatric Kidney Transplant Recipients

Simultaneous activation of the intrinsic and extrinsic pathways by histone deacetylase (HDAC) inhibitors and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) synergistically induces mitochondrial damage and apoptosis in human leukemia cells

Interruption of the Ras/MEK/ERK signaling cascade enhances Chk1 inhibitor–induced DNA damage in vitro and in vivo in human multiple myeloma cells

Role of histone deacetylase inhibitor-induced reactive oxygen species and DNA damage in LAQ-824/fludarabine antileukemic interactions

Cytokinetically quiescent (G0/G1) human multiple myeloma cells are susceptible to simultaneous inhibition of Chk1 and MEK1/2

Su1804 Macrophage Phenotypes in Humans With NAFLD

The utility of ETV1, ETV4 and ETV5 RNA in‐situ hybridization in the diagnosis of CIC–DUX sarcomas

Analytical Validation and Clinical Utilization of the Oncomine Comprehensive Assay Plus Panel for Comprehensive Genomic Profiling in Solid Tumors

Intrahepatic Cholangiocarcinoma Progression: Prognostic Factors and Basic Mechanisms

The Sensitivity and Specificity of Touch Preparation for Rapid Diagnosis of Invasive Fungal Sinusitis: A Pilot Study

Histone Deacetylase Inhibitors Activate NF-κB in Human Leukemia Cells through an ATM/NEMO-related Pathway

The Histone Deacetylase Inhibitor LAQ824 Induces Human Leukemia Cell Death through a Process Involving XIAP Down-Regulation, Oxidative Injury, and the Acid Sphingomyelinase-Dependent Generation of Ceramide

Histone deacetylase inhibitors activate NF-κB in human leukemia cells through an ATM/NEMO-related pathway

Quality control material for the detection of somatic mutations in fixed clinical specimens by next-generation sequencing

Flavopiridol and Histone Deacetylase Inhibitors Promote Mitochondrial Injury and Cell Death in Human Leukemia Cells That Overexpress Bcl-2

Mechanism and functional role of XIAP and Mcl-1 down-regulation in flavopiridol/vorinostat antileukemic interactions

Disruption of Src function potentiates Chk1-inhibitor–induced apoptosis in human multiple myeloma cells in vitro and in vivo

The Sensitivity and Specificity of Touch Preparation for Rapid Diagnosis of Invasive Fungal Sinusitis: A Pilot Study

Preclinical assessment of simultaneous targeting of epidermal growth factor receptor (ErbB1) and ErbB2 as a strategy for cholangiocarcinoma therapy

Induction of apoptosis in human leukemia cells by the tyrosine kinase inhibitor adaphostin proceeds through a RAF-1 MEK ERK- and AKT-dependent process

Potentiation of the lethality of the histone deacetylase inhibitor LAQ824 by the cyclin-dependent kinase inhibitor roscovitine in human leukemia cells

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