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Cognitive and behavior deficits in sickle cell mice are associated with profound neuropathologic changes in hippocampus and cerebellum

Neurobiology of disease, 2016-01, Vol.85, p.60-72

2016

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RON kinase inhibition reduces renal endothelial injury in sickle cell disease mice

Haematologica (Roma), 2018-05, Vol.103 (5), p.787-798

2018

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The corticosteroid compounds prednisolone and vamorolone do not alter the nociception phenotype and exacerbate liver injury in sickle cell mice

Scientific reports, 2018-04, Vol.8 (1), p.6081-11, Article 6081

2018

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The opioid antagonist naltrexone inhibits activity and alters expression of α7 and α4β2 nicotinic receptors in hippocampal neurons: implications for smoking cessation programs

Neuropharmacology, 2000-12, Vol.39 (13), p.2740-2755

2000

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Nicotine at concentrations found in cigarette smokers activates and desensitizes nicotinic acetylcholine receptors in CA1 interneurons of rat hippocampus

Neuropharmacology, 2000-10, Vol.39 (13), p.2726-2739

2000

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Circulating mitochondrial DNA is a proinflammatory DAMP in sickle cell disease

Blood, 2021-06, Vol.137 (22), p.3116-3126

2021

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NLRP3 Inflammasome-Mediated Platelet Activation and Thrombus Formation in Sickle Cell Mice Can be Targeted By the BTK Inhibitor Ibrutinib

Blood, 2023-11, Vol.142 (Supplement 1), p.3935-3935

2023

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Syk inhibition suppresses NLRP3 inflammasome activation in platelets from sickle cell mice leading to decreased platelet secretion, aggregation, spreading, and in vitro thrombus formation

Thrombosis research, 2024-05, Vol.237, p.18-22

2024

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Mouse models of sickle cell disease: Imperfect and yet very informative

Blood cells, molecules, & diseases, 2024-01, Vol.104, p.102776-102776, Article 102776

2024

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Modulation of social deficits and repetitive behaviors in a mouse model of autism: the role of the nicotinic cholinergic system

Psychopharmacology, 2015-12, Vol.232 (23), p.4303-4316

2015

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Calcium flux alterations in erythrocytes from sickle cell mice: The relevance of mean corpuscular volume

Blood cells, molecules, & diseases, 2024-01, Vol.104, p.102800-102800, Article 102800

2024

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NLRP3 inflammasome and bruton tyrosine kinase inhibition interferes with upregulated platelet aggregation and in vitro thrombus formation in sickle cell mice

Biochemical and biophysical research communications, 2021-05, Vol.555, p.196-201

2021

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Nitrite decreases sickle hemoglobin polymerization in vitro independently of methemoglobin formation

Toxicology and applied pharmacology, 2023-08, Vol.473, p.116606-116606, Article 116606

2023

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Nitric oxide and sickle cell disease—Is there a painful connection?

Experimental biology and medicine (Maywood, N.J.), 2021-02, Vol.246 (3), p.332-341

2021

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Mitapivat increases ATP and decreases oxidative stress and erythrocyte mitochondria retention in a SCD mouse model

Blood cells, molecules, & diseases, 2022-07, Vol.95, p.102660-102660, Article 102660

2022

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Locomotor mal-performance and gait adaptability deficits in sickle cell mice are associated with vascular and white matter abnormalities and oxidative stress in cerebellum

Brain research, 2020-11, Vol.1746, p.146968-146968, Article 146968

2020

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Altered nocifensive behavior in animal models of autism spectrum disorder: The role of the nicotinic cholinergic system

Neuropharmacology, 2016-12, Vol.111, p.323-334

2016

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Sickle cell disease subjects and mouse models have elevated nitrite and cGMP levels in blood compartments

Nitric oxide, 2020-01, Vol.94, p.79-91

2020

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Sickle cell disease mice have cerebral oxidative stress and vascular and white matter abnormalities

Blood cells, molecules, & diseases, 2021-02, Vol.86, p.102493-102493, Article 102493

2021

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Rapamycin increases fetal hemoglobin and ameliorates the nociception phenotype in sickle cell mice

Blood cells, molecules, & diseases, 2015-12, Vol.55 (4), p.363-372

2015

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Sensitivity of neuronal nicotinic acetylcholine receptors to the opiate antagonists naltrexone and naloxone: receptor blockade and up-regulation

Bioorganic & medicinal chemistry letters, 2004-04, Vol.14 (8), p.1879-1887

2004

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Blood collection vials and clinically used intravenous fluids contain significant amounts of nitrite

Free radical biology & medicine, 2017-07, Vol.108, p.533-541

2017

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Dexmedetomidine ameliorates nocifensive behavior in humanized sickle cell mice

European journal of pharmacology, 2015-05, Vol.754, p.125-133

2015

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Nicotinic cholinergic system alterations and nitrous oxide exposure in a mouse model: a hypothesis for the pathobiology of autism spectrum disorder

Psychopharmacology, 2017, Vol.234 (2), p.317-318

2017

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The role of nitrite in muscle function, susceptibility to contraction injury, and fatigability in sickle cell mice

Nitric oxide, 2018-11, Vol.80, p.70-81

2018

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Cognitive and behavior deficits in sickle cell mice are associated with profound neuropathologic changes in hippocampus and cerebellum

RON kinase inhibition reduces renal endothelial injury in sickle cell disease mice

The corticosteroid compounds prednisolone and vamorolone do not alter the nociception phenotype and exacerbate liver injury in sickle cell mice

The opioid antagonist naltrexone inhibits activity and alters expression of α7 and α4β2 nicotinic receptors in hippocampal neurons: implications for smoking cessation programs

Nicotine at concentrations found in cigarette smokers activates and desensitizes nicotinic acetylcholine receptors in CA1 interneurons of rat hippocampus

Circulating mitochondrial DNA is a proinflammatory DAMP in sickle cell disease

NLRP3 Inflammasome-Mediated Platelet Activation and Thrombus Formation in Sickle Cell Mice Can be Targeted By the BTK Inhibitor Ibrutinib

Syk inhibition suppresses NLRP3 inflammasome activation in platelets from sickle cell mice leading to decreased platelet secretion, aggregation, spreading, and in vitro thrombus formation

Mouse models of sickle cell disease: Imperfect and yet very informative

Modulation of social deficits and repetitive behaviors in a mouse model of autism: the role of the nicotinic cholinergic system

Calcium flux alterations in erythrocytes from sickle cell mice: The relevance of mean corpuscular volume

NLRP3 inflammasome and bruton tyrosine kinase inhibition interferes with upregulated platelet aggregation and in vitro thrombus formation in sickle cell mice

Nitrite decreases sickle hemoglobin polymerization in vitro independently of methemoglobin formation

Nitric oxide and sickle cell disease—Is there a painful connection?

Mitapivat increases ATP and decreases oxidative stress and erythrocyte mitochondria retention in a SCD mouse model

Locomotor mal-performance and gait adaptability deficits in sickle cell mice are associated with vascular and white matter abnormalities and oxidative stress in cerebellum

Altered nocifensive behavior in animal models of autism spectrum disorder: The role of the nicotinic cholinergic system

Sickle cell disease subjects and mouse models have elevated nitrite and cGMP levels in blood compartments

Sickle cell disease mice have cerebral oxidative stress and vascular and white matter abnormalities

Rapamycin increases fetal hemoglobin and ameliorates the nociception phenotype in sickle cell mice

Sensitivity of neuronal nicotinic acetylcholine receptors to the opiate antagonists naltrexone and naloxone: receptor blockade and up-regulation

Blood collection vials and clinically used intravenous fluids contain significant amounts of nitrite

Dexmedetomidine ameliorates nocifensive behavior in humanized sickle cell mice

Nicotinic cholinergic system alterations and nitrous oxide exposure in a mouse model: a hypothesis for the pathobiology of autism spectrum disorder

The role of nitrite in muscle function, susceptibility to contraction injury, and fatigability in sickle cell mice

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