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Unique residues in the ATP gated human P2X7 receptor define a novel allosteric binding pocket for the selective antagonist AZ10606120

Scientific reports, 2017-04, Vol.7 (1), p.725-12, Article 725

2017

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A rapid RT-LAMP SARS-CoV-2 screening assay for collapsing asymptomatic COVID-19 transmission

PloS one, 2022-09, Vol.17 (9), p.e0273912

2022

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Contribution of the Juxtatransmembrane Intracellular Regions to the Time Course and Permeation of ATP-gated P2X7 Receptor Ion Channels

The Journal of biological chemistry, 2015-06, Vol.290 (23), p.14556-14566

2015

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Circulating tumour DNA dynamics during alternating chemotherapy and hormonal therapy in metastatic breast cancer: the ALERT study

Breast cancer research and treatment, 2024-07, Vol.206 (2), p.377-385

2024

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Mapping the Allosteric Action of Antagonists A740003 and A438079 Reveals a Role for the Left Flipper in Ligand Sensitivity at P2X7 Receptors

Molecular pharmacology, 2018-05, Vol.93 (5), p.553-562

2018

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Meta-Analysis of Circulating Tumor Cell PD-L1 Expression and the Association with Clinical Outcomes in Non-Small Cell Lung Cancer

Clinical chemistry (Baltimore, Md.), 2024-01, Vol.70 (1), p.234-249

2024

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How to design and implement a university-based COVID-19 testing programme? An evaluation of a novel RT-LAMP COVID-19 testing programme in a UK university

BMC health services research, 2022-12, Vol.22 (1), p.1502-8, Article 1502

2022

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Shallow WGS of individual CTCs identifies actionable targets for informing treatment decisions in metastatic breast cancer

British journal of cancer, 2022-11, Vol.127 (10), p.1858-1864

2022

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A Rapid, Shallow Whole Genome Sequencing Workflow Applicable to Limiting Amounts of Cell-Free DNA

Clinical chemistry (Baltimore, Md.), 2023-04, Vol.69 (5), p.510-518

2023

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Induction of APOBEC3B expression by chemotherapy drugs is mediated by DNA-PK-directed activation of NF-κB

Oncogene, 2021-02, Vol.40 (6), p.1077-1090

2021

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The Intracellular Amino Terminus Plays a Dominant Role in Desensitization of ATP-gated P2X Receptor Ion Channels

The Journal of biological chemistry, 2011-12, Vol.286 (52), p.44691-44701

2011

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Lipid Raft Association and Cholesterol Sensitivity of P2X1-4 Receptors for ATP: CHIMERAS AND POINT MUTANTS IDENTIFY INTRACELLULAR AMINO-TERMINAL RESIDUES INVOLVED IN LIPID REGULATION OF P2X1 RECEPTORS

The Journal of biological chemistry, 2010-10, Vol.285 (43), p.32770-32777

2010

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Agonist binding evokes extensive conformational changes in the extracellular domain of the ATP-gated human P2X1 receptor ion channel

Proceedings of the National Academy of Sciences - PNAS, 2012-03, Vol.109 (12), p.4663-4667

2012

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Cysteine scanning mutagenesis (residues Glu52-Gly96) of the human P2X1 receptor for ATP: mapping agonist binding and channel gating

The Journal of biological chemistry, 2011-08, Vol.286 (33), p.29207-29217

2011

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The Evolution of Affordable Technologies in Liquid Biopsy Diagnostics: The Key to Clinical Implementation

Cancers, 2023-11, Vol.15 (22), p.5434

2023

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P2X Receptor Chimeras Highlight Roles of the Amino Terminus to Partial Agonist Efficacy, the Carboxyl Terminus to Recovery from Desensitization, and Independent Regulation of Channel Transitions

The Journal of biological chemistry, 2013-07, Vol.288 (29), p.21412-21421

2013

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Contribution of the region Glu181 to Val200 of the extracellular loop of the human P2X1 receptor to agonist binding and gating revealed using cysteine scanning mutagenesis

Journal of neurochemistry, 2009-05, Vol.109 (4), p.1042-1052

2009

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Lipid Raft Association and Cholesterol Sensitivity of P2X1-4 Receptors for ATP

The Journal of biological chemistry, 2010-10, Vol.285 (43), p.32770-32777

2010

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Contribution of the region Glu181 to Val200 of the extracellular loop of the human P2X1 receptor to agonist binding and gating revealed using cysteine scanning mutagenesis1

Journal of neurochemistry, 2009-05, Vol.109 (4), p.1042-1052

2009

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Induction of APOBEC3B expression by chemotherapy drugs is mediated by DNA-PK-directed activation of NF-[kappa]B

Oncogene, 2021-02, Vol.40 (6), p.1077

2021

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A novel hotspot specific isothermal amplification method for detection of the common PIK3CA p.H1047R breast cancer mutation

Scientific reports, 2020-03, Vol.10 (1), p.4553, Article 4553

2020

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Design and implementation of a university-based COVID-19 testing programme: an observational study

The Lancet (British edition), 2021-11, Vol.398, p.S24-S24

2021

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Serial postoperative ctDNA monitoring of breast cancer recurrence

Journal of clinical oncology, 2022-06, Vol.40 (16_suppl), p.562-562

2022

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Unique residues in the ATP gated human P2X7 receptor define a novel allosteric binding pocket for the selective antagonist AZ10606120

A rapid RT-LAMP SARS-CoV-2 screening assay for collapsing asymptomatic COVID-19 transmission

Contribution of the Juxtatransmembrane Intracellular Regions to the Time Course and Permeation of ATP-gated P2X7 Receptor Ion Channels

Circulating tumour DNA dynamics during alternating chemotherapy and hormonal therapy in metastatic breast cancer: the ALERT study

Mapping the Allosteric Action of Antagonists A740003 and A438079 Reveals a Role for the Left Flipper in Ligand Sensitivity at P2X7 Receptors

Meta-Analysis of Circulating Tumor Cell PD-L1 Expression and the Association with Clinical Outcomes in Non-Small Cell Lung Cancer

How to design and implement a university-based COVID-19 testing programme? An evaluation of a novel RT-LAMP COVID-19 testing programme in a UK university

Genome engineering for estrogen receptor mutations reveals differential responses to anti-estrogens and new prognostic gene signatures for breast cancer

Shallow WGS of individual CTCs identifies actionable targets for informing treatment decisions in metastatic breast cancer

A Rapid, Shallow Whole Genome Sequencing Workflow Applicable to Limiting Amounts of Cell-Free DNA

Induction of APOBEC3B expression by chemotherapy drugs is mediated by DNA-PK-directed activation of NF-κB

The Intracellular Amino Terminus Plays a Dominant Role in Desensitization of ATP-gated P2X Receptor Ion Channels

Lipid Raft Association and Cholesterol Sensitivity of P2X1-4 Receptors for ATP: CHIMERAS AND POINT MUTANTS IDENTIFY INTRACELLULAR AMINO-TERMINAL RESIDUES INVOLVED IN LIPID REGULATION OF P2X1 RECEPTORS

Agonist binding evokes extensive conformational changes in the extracellular domain of the ATP-gated human P2X1 receptor ion channel

Cysteine scanning mutagenesis (residues Glu52-Gly96) of the human P2X1 receptor for ATP: mapping agonist binding and channel gating

The Evolution of Affordable Technologies in Liquid Biopsy Diagnostics: The Key to Clinical Implementation

P2X Receptor Chimeras Highlight Roles of the Amino Terminus to Partial Agonist Efficacy, the Carboxyl Terminus to Recovery from Desensitization, and Independent Regulation of Channel Transitions

Serial Postoperative Circulating Tumor DNA Assessment Has Strong Prognostic Value During Long-Term Follow-Up in Patients With Breast Cancer

Contribution of the region Glu181 to Val200 of the extracellular loop of the human P2X1 receptor to agonist binding and gating revealed using cysteine scanning mutagenesis

Lipid Raft Association and Cholesterol Sensitivity of P2X1-4 Receptors for ATP

Contribution of the region Glu181 to Val200 of the extracellular loop of the human P2X1 receptor to agonist binding and gating revealed using cysteine scanning mutagenesis1

Induction of APOBEC3B expression by chemotherapy drugs is mediated by DNA-PK-directed activation of NF-[kappa]B

A novel hotspot specific isothermal amplification method for detection of the common PIK3CA p.H1047R breast cancer mutation

Design and implementation of a university-based COVID-19 testing programme: an observational study

Serial postoperative ctDNA monitoring of breast cancer recurrence

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