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An antigen-specific immunotherapeutic, AKS-107, deletes insulin-specific B cells and prevents murine autoimmune diabetes

Frontiers in immunology, 2024-03, Vol.15, p.1367514-1367514

2024

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Tumor-induced immune dysfunction: the macrophage connection

Journal of leukocyte biology, 1998-09, Vol.64 (3), p.275-290

1998

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Immunogenicity phase II study evaluating booster capacity of nonadjuvanted AKS-452 SARS-Cov-2 RBD Fc vaccine

npj vaccines, 2024-02, Vol.9 (1), p.40-40, Article 40

2024

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Reversal of Hyperglycemia and Suppression of Type 1 Diabetes in the NOD Mouse with Apoptotic DNA Immunotherapy™ (ADi™), ADi-100

Biomedicines, 2020-03, Vol.8 (3), p.53

2020

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Immunological Characterization and Therapeutic Activity of an Altered-Peptide Ligand, NBI-6024, Based on the Immunodominant Type 1 Diabetes Autoantigen Insulin B-Chain (9–23) Peptide

Diabetes (New York, N.Y.), 2002-07, Vol.51 (7), p.2126-2134

2002

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Development of an IgG-Fc fusion COVID-19 subunit vaccine, AKS-452

Vaccine, 2021-10, Vol.39 (45), p.6601-6613

2021

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Pharmacological characterization of CXC chemokine receptor 3 ligands and a small molecule antagonist

The Journal of pharmacology and experimental therapeutics, 2005-06, Vol.313 (3), p.1263-1271

2005

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Regulation of murine macrophage proinflammatory and anti-inflammatory cytokines by ligands for peroxisome proliferator-activated receptor-γ: counter-regulatory activity by IFN-γ

Journal of leukocyte biology, 2002-04, Vol.71 (4), p.677-685

2002

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Enhanced early innate and T cell-mediated responses in subjects immunized with Anthrax Vaccine Adsorbed Plus CPG 7909 (AV7909)

Vaccine, 2014-11, Vol.32 (50), p.6847-6854

2014

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Identification of CC Chemokine Receptor 7 Residues Important for Receptor Activation

The Journal of biological chemistry, 2004-10, Vol.279 (41), p.42383-42392

2004

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Cutting Edge: Diabetes-Associated Quantitative Trait Locus, Idd4, Is Responsible for the IL-12p40 Overexpression Defect in Nonobese Diabetic (NOD) Mice

The Journal of immunology (1950), 2003-10, Vol.171 (7), p.3333-3337

2003

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A disease-associated cellular immune response in type 1 diabetics to an immunodominant epitope of insulin

The Journal of clinical investigation, 2001-01, Vol.107 (2), p.173-180

2001

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SJL and NOD macrophages are uniquely characterized by genetically programmed, elevated expression of the IL-12(p40) gene, suggesting a conserved pathway for the induction of organ-specific autoimmunity

Journal of leukocyte biology, 2001-03, Vol.69 (3), p.440-448

2001

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Intrinsic Defects in Macrophage IL-12 Production Associated with Immune Dysfunction in the MRL/++ and New Zealand Black/White F1 Lupus-Prone Mice and the Leishmania major-Susceptible BALB/c Strain

The Journal of immunology (1950), 1998-12, Vol.161 (12), p.6878-6884

1998

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Assessment of the Severity and the Remission Criteria in Eosinophilic Esophagitis

Biomedicines, 2023-12, Vol.11 (12), p.3204

2023

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A high-throughput chemotaxis assay for pharmacological characterization of chemokine receptors: Utilization of U937 monocytic cells

Journal of pharmacological and toxicological methods, 2005-03, Vol.51 (2), p.105-114

2005

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Aberrant macrophage cytokine production is a conserved feature among autoimmune-prone mouse strains: elevated interleukin (IL)-12 and an imbalance in tumor necrosis factor-alpha and IL-10 define a unique cytokine profile in macrophages from young nonobese diabetic mice

Diabetes (New York, N.Y.), 2000-07, Vol.49 (7), p.1106-1115

2000

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Tumor-induced regulation of suppressor macrophage nitric oxide and TNF-alpha production. Role of tumor-derived IL-10, TGF-beta, and prostaglandin E2

The Journal of immunology (1950), 1994-08, Vol.153 (4), p.1674-1686

1994

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IL-15 functions as a potent autocrine regulator of macrophage proinflammatory cytokine production: evidence for differential receptor subunit utilization associated with stimulation or inhibition

The Journal of immunology (1950), 1997-09, Vol.159 (6), p.2941-2951

1997

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Taxol, a microtubule-stabilizing antineoplastic agent, differentially regulates normal and tumor-bearing host macrophage nitric oxide production

Immunopharmacology, 1997-08, Vol.37 (1), p.63-73

1997

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Aberrant cytokine expression and autocrine regulation characterize macrophages from young MRL+/+ and NZB/W F1 lupus-prone mice

The Journal of immunology (1950), 1997-12, Vol.159 (11), p.5610-5619

1997

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Immunological characterization and therapeutic activity of an altered-peptide ligand, NBI-6024, based on the immunodominant type 1 diabetes autoantigen insulin B-chain

Diabetes (New York, N.Y.), 2002-07, Vol.51 (7), p.2126

2002

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Cuttine edge: diabetes-associated quantitative trait locus, Idd4, is responsible for the IL-12p40 overexpression defect in nonobese diabetic (NOD) mice

The Journal of immunology (1950), 2003-10, Vol.171 (7), p.3333-3337

2003

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An antigen-specific immunotherapeutic, AKS-107, deletes insulin-specific B cells and prevents murine autoimmune diabetes

Tumor-induced immune dysfunction: the macrophage connection

Immunogenicity phase II study evaluating booster capacity of nonadjuvanted AKS-452 SARS-Cov-2 RBD Fc vaccine

Reversal of Hyperglycemia and Suppression of Type 1 Diabetes in the NOD Mouse with Apoptotic DNA Immunotherapy™ (ADi™), ADi-100

Immunological Characterization and Therapeutic Activity of an Altered-Peptide Ligand, NBI-6024, Based on the Immunodominant Type 1 Diabetes Autoantigen Insulin B-Chain (9–23) Peptide

Development of an IgG-Fc fusion COVID-19 subunit vaccine, AKS-452

Pharmacological characterization of CXC chemokine receptor 3 ligands and a small molecule antagonist

A randomized phase I/II safety and immunogenicity study of the Montanide-adjuvanted SARS-CoV-2 spike protein-RBD-Fc vaccine, AKS-452

Regulation of murine macrophage proinflammatory and anti-inflammatory cytokines by ligands for peroxisome proliferator-activated receptor-γ: counter-regulatory activity by IFN-γ

Phase I interim results of a phase I/II study of the IgG-Fc fusion COVID-19 subunit vaccine, AKS-452

Enhanced early innate and T cell-mediated responses in subjects immunized with Anthrax Vaccine Adsorbed Plus CPG 7909 (AV7909)

Identification of CC Chemokine Receptor 7 Residues Important for Receptor Activation

Cutting Edge: Diabetes-Associated Quantitative Trait Locus, Idd4, Is Responsible for the IL-12p40 Overexpression Defect in Nonobese Diabetic (NOD) Mice

A disease-associated cellular immune response in type 1 diabetics to an immunodominant epitope of insulin

SJL and NOD macrophages are uniquely characterized by genetically programmed, elevated expression of the IL-12(p40) gene, suggesting a conserved pathway for the induction of organ-specific autoimmunity

Intrinsic Defects in Macrophage IL-12 Production Associated with Immune Dysfunction in the MRL/++ and New Zealand Black/White F1 Lupus-Prone Mice and the Leishmania major-Susceptible BALB/c Strain

Assessment of the Severity and the Remission Criteria in Eosinophilic Esophagitis

A high-throughput chemotaxis assay for pharmacological characterization of chemokine receptors: Utilization of U937 monocytic cells

Aberrant macrophage cytokine production is a conserved feature among autoimmune-prone mouse strains: elevated interleukin (IL)-12 and an imbalance in tumor necrosis factor-alpha and IL-10 define a unique cytokine profile in macrophages from young nonobese diabetic mice

Tumor-induced regulation of suppressor macrophage nitric oxide and TNF-alpha production. Role of tumor-derived IL-10, TGF-beta, and prostaglandin E2

IL-15 functions as a potent autocrine regulator of macrophage proinflammatory cytokine production: evidence for differential receptor subunit utilization associated with stimulation or inhibition

Taxol, a microtubule-stabilizing antineoplastic agent, differentially regulates normal and tumor-bearing host macrophage nitric oxide production

Aberrant cytokine expression and autocrine regulation characterize macrophages from young MRL+/+ and NZB/W F1 lupus-prone mice

Immunological characterization and therapeutic activity of an altered-peptide ligand, NBI-6024, based on the immunodominant type 1 diabetes autoantigen insulin B-chain

Cuttine edge: diabetes-associated quantitative trait locus, Idd4, is responsible for the IL-12p40 overexpression defect in nonobese diabetic (NOD) mice

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