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The microbiome and disease: reviewing the links between the oral microbiome, aging, and Alzheimer's disease

Journal of Alzheimer's disease, 2015-01, Vol.43 (3), p.725-738

2015

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GDNF, NGF and BDNF as therapeutic options for neurodegeneration

Pharmacology & therapeutics (Oxford), 2013-05, Vol.138 (2), p.155-175

2013

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16S rRNA Next Generation Sequencing Analysis Shows Bacteria in Alzheimer's Post-Mortem Brain

Frontiers in aging neuroscience, 2017-06, Vol.9, p.195

2017

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The Neurotrophins and Their Role in Alzheimers Disease

Current neuropharmacology, 2011-12, Vol.9 (4), p.559-573

2011

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Clinical relevance of the neurotrophins and their receptors

Clinical science (1979), 2006-02, Vol.110 (2), p.175-191

2006

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High resolution 16S rRNA gene Next Generation Sequencing study of brain areas associated with Alzheimer's and Parkinson's disease

Frontiers in aging neuroscience, 2022-12, Vol.14, p.1026260-1026260

2022

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Biological Activity of Nerve Growth Factor Precursor Is Dependent upon Relative Levels of Its Receptors

The Journal of biological chemistry, 2009-07, Vol.284 (27), p.18424-18433

2009

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Comparison of Blood Bacterial Communities in Periodontal Health and Periodontal Disease

Frontiers in cellular and infection microbiology, 2021-01, Vol.10, p.577485

2021

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Stepwise, non-adherent differentiation of human pluripotent stem cells to generate basal forebrain cholinergic neurons via hedgehog signaling

Stem cell research, 2013-11, Vol.11 (3), p.1206-1221

2013

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Mini Review: Opposing Pathologies in Cancer and Alzheimer's Disease: Does the PI3K/Akt Pathway Provide Clues?

Frontiers in endocrinology (Lausanne), 2020-06, Vol.11, p.403-403

2020

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Premorbid effects of APOE on synaptic proteins in human temporal neocortex

Neurobiology of aging, 2006-06, Vol.27 (6), p.797-803

2006

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Targeting Nerve Growth Factor in Pain: What is the Therapeutic Potential?

BioDrugs : clinical immunotherapeutics, biopharmaceuticals, and gene therapy, 2008-01, Vol.22 (6), p.349-359

2008

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Treatment of murine osteoarthritis with TrkAd5 reveals a pivotal role for nerve growth factor in non-inflammatory joint pain

Pain (Amsterdam), 2010-05, Vol.149 (2), p.386-392

2010

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Activation of a synapse weakening pathway by human Val66 but not Met66 pro-brain-derived neurotrophic factor (proBDNF)

Pharmacological research, 2016-02, Vol.104, p.97-107

2016

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TrkAd5: A novel therapeutic agent for treatment of inflammatory pain and asthma

The Journal of pharmacology and experimental therapeutics, 2006-03, Vol.316 (3), p.1122-1129

2006

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alpha- and beta-secretase: profound changes in Alzheimer's disease

Biochemical and biophysical research communications, 2002-12, Vol.299 (3), p.373-376

2002

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Design and Nuclear Magnetic Resonance (NMR) Structure Determination of the Second Extracellular Immunoglobulin Tyrosine Kinase A (TrkAIg2) Domain Construct for Binding Site Elucidation in Drug Discovery

Journal of medicinal chemistry, 2015-01, Vol.58 (2), p.767-777

2015

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A Discrete Domain of the Human TrkB Receptor Defines the Binding Sites for BDNF and NT-4

Biochemical and biophysical research communications, 2002-03, Vol.291 (3), p.501-507

2002

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Identification of novel small molecule TGF-β antagonists using structure-based drug design

Journal of computer-aided molecular design, 2013-04, Vol.27 (4), p.365-372

2013

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DECREASE IN BLADDER OVERACTIVITY WITH REN1820 IN RATS WITH CYCLOPHOSPHAMIDE INDUCED CYSTITIS

The Journal of urology, 2005-03, Vol.173 (3), p.1016-1021

2005

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Specificity in Trk Receptor:Neurotrophin Interactions: The Crystal Structure of TrkB-d5 in Complex with Neurotrophin-4/5

Structure (London), 2001-12, Vol.9 (12), p.1191-1199

2001

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Galanin Regulates the Postnatal Survival of a Subset of Basal Forebrain Cholinergic Neurons

Proceedings of the National Academy of Sciences - PNAS, 2000-10, Vol.97 (21), p.11569-11574

2000

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Profound and Selective Loss of Catalytic TrkB Immunoreactivity in Alzheimer's Disease

Biochemical and biophysical research communications, 1999-11, Vol.264 (3), p.648-651

1999

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Human ProNGF: biological effects and binding profiles at TrkA, P75NTR and sortilin

Journal of neurochemistry, 2008-11, Vol.107 (4), p.1124-1135

2008

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A feasibility study to recruit, retain and treat periodontitis in volunteers with mild dementia, whilst monitoring their cognition

Journal of dentistry, 2024-11, Vol.150, p.105355, Article 105355

2024

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The microbiome and disease: reviewing the links between the oral microbiome, aging, and Alzheimer's disease

GDNF, NGF and BDNF as therapeutic options for neurodegeneration

16S rRNA Next Generation Sequencing Analysis Shows Bacteria in Alzheimer's Post-Mortem Brain

The Neurotrophins and Their Role in Alzheimers Disease

Clinical relevance of the neurotrophins and their receptors

High resolution 16S rRNA gene Next Generation Sequencing study of brain areas associated with Alzheimer's and Parkinson's disease

Biological Activity of Nerve Growth Factor Precursor Is Dependent upon Relative Levels of Its Receptors

Comparison of Blood Bacterial Communities in Periodontal Health and Periodontal Disease

Stepwise, non-adherent differentiation of human pluripotent stem cells to generate basal forebrain cholinergic neurons via hedgehog signaling

Mini Review: Opposing Pathologies in Cancer and Alzheimer's Disease: Does the PI3K/Akt Pathway Provide Clues?

Premorbid effects of APOE on synaptic proteins in human temporal neocortex

Targeting Nerve Growth Factor in Pain: What is the Therapeutic Potential?

Treatment of murine osteoarthritis with TrkAd5 reveals a pivotal role for nerve growth factor in non-inflammatory joint pain

Activation of a synapse weakening pathway by human Val66 but not Met66 pro-brain-derived neurotrophic factor (proBDNF)

TrkAd5: A novel therapeutic agent for treatment of inflammatory pain and asthma

alpha- and beta-secretase: profound changes in Alzheimer's disease

Design and Nuclear Magnetic Resonance (NMR) Structure Determination of the Second Extracellular Immunoglobulin Tyrosine Kinase A (TrkAIg2) Domain Construct for Binding Site Elucidation in Drug Discovery

A Discrete Domain of the Human TrkB Receptor Defines the Binding Sites for BDNF and NT-4

Identification of novel small molecule TGF-β antagonists using structure-based drug design

DECREASE IN BLADDER OVERACTIVITY WITH REN1820 IN RATS WITH CYCLOPHOSPHAMIDE INDUCED CYSTITIS

Specificity in Trk Receptor:Neurotrophin Interactions: The Crystal Structure of TrkB-d5 in Complex with Neurotrophin-4/5

Galanin Regulates the Postnatal Survival of a Subset of Basal Forebrain Cholinergic Neurons

Profound and Selective Loss of Catalytic TrkB Immunoreactivity in Alzheimer's Disease

Human ProNGF: biological effects and binding profiles at TrkA, P75NTR and sortilin

A feasibility study to recruit, retain and treat periodontitis in volunteers with mild dementia, whilst monitoring their cognition

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