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Preclinical evaluation for engraftment of CD34+ cells gene-edited at the sickle cell disease locus in xenograft mouse and non-human primate models

Cell reports. Medicine, 2021-04, Vol.2 (4), p.100247-100247, Article 100247

2021

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CRISPR-Cas9 gene repair of hematopoietic stem cells from patients with X-linked chronic granulomatous disease

Science translational medicine, 2017-01, Vol.9 (372)

2017

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Development of Anti-Human Mesothelin-Targeted Chimeric Antigen Receptor Messenger RNA-Transfected Peripheral Blood Lymphocytes for Ovarian Cancer Therapy

Human gene therapy, 2018-05, Vol.29 (5), p.614

2018

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Influence of Helicobacter pylori on reactive oxygen-induced gastric epithelial cell injury

Carcinogenesis (New York), 2000-11, Vol.21 (11), p.2091-2095

2000

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Gene Editing and mRNA-Based Therapy: Two Complementary Therapeutic Approaches for the Treatment of Patients with Xmen Disease

Blood, 2019-11, Vol.134 (Supplement_1), p.4637-4637

2019

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Preclinical Evaluation for Engraftment of Gene-Edited CD34+ Cells with a Sickle Cell Disease Mutation in a Rhesus Transplantation Model

Blood, 2019-11, Vol.134 (Supplement_1), p.609-609

2019

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Abstract 3748: Development of anti-human mesothelin chimeric antigen receptor (CAR) messenger RNA (mRNA) transfected peripheral blood mononuclear cells (CARMA) for the treatment of mesothelin-expressing cancers

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.3748-3748

2017

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MAGT1 messenger RNA-corrected autologous T and natural killer cells for potential cell therapy in X-linked immunodeficiency with magnesium defect, Epstein-Barr virus infection and neoplasia disease

Cytotherapy (Oxford, England), 2021-03, Vol.23 (3), p.203-210

2021

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Expression of chimeric antigen receptors in natural killer cells with a regulatory-compliant non-viral method

Cancer gene therapy, 2010-03, Vol.17 (3), p.147-154

2010

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p53 and p14 increase sensitivity of gastric cells to H. pylori-induced apoptosis

Digestive diseases and sciences, 2003-07, Vol.48 (7), p.1284-1291

2003

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Effects of Helicobacter pylori on proliferation of gastric epithelial cells in vitro

The American journal of gastroenterology, 1999-06, Vol.94 (6), p.1508-1511

1999

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Efficient large volume lentiviral vector production using flow electroporation

Human gene therapy, 2012-02, Vol.23 (2), p.243

2012

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Delivery of whole tumor lysate into dendritic cells for cancer vaccination

Methods in molecular biology (Clifton, N.J.), 2008, Vol.423, p.139

2008

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Large volume flow electroporation of mRNA: clinical scale process

Methods in molecular biology (Clifton, N.J.), 2013, Vol.969, p.127

2013

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Development of ‘enhanced’ potency immunotherapy products using nonviral approaches

Pharmaceutical bioprocessing, 2015-11, Vol.3 (7), p.463-470

2015

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A Highly Efficient, Clinically Applicable Transfection Method to Redirect the Specificity of Immune Cells and Enhance Their Anti-Tumor Capacity

Blood, 2008-11, Vol.112 (11), p.3894-3894

2008

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An Improved, Non-Viral Approach for Production of hCD40L+ B-CLL Cells for Cancer Immunotherapy

Blood, 2006-11, Vol.108 (11), p.2107-2107

2006

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Helicobacter pylori inhibits gastric cell cycle progression

Microbes and infection, 2000-08, Vol.2 (10), p.1159-1169

2000

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A method for establishing primary cultures of human gastric epithelial cells

Methods in cell science, 2000, Vol.22 (2-3), p.133-136

2000

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816. Rapid, Consistent and Scalable Production of Viral Vectors in Suspension Cells by Cotransfection of Viral Component Plasmid DNA or RNA

Molecular therapy, 2006-05, Vol.13 (S1), p.S317-S317

2006

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Highly Efficient, Large Volume Flow Electroporation

Technology in cancer research & treatment, 2002-10, Vol.1 (5), p.341-349

2002

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Efficient responses in a murine renal tumor model by electroloading dendritic cells with whole-tumor lysate

Journal of immunotherapy (1997), 2005-11, Vol.28 (6), p.542

2005

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Stimulation of reactive oxygen species within gastric epithelial cells by H. pylori is responsible for the increase in p53 protein levels

Gastroenterology (New York, N.Y. 1943), 2001-04, Vol.120 (5), p.A87-A87

2001

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H. pylori induced alterations in MDM2 and P14ARF expression in gastric epithelial cells

Gastroenterology (New York, N.Y. 1943), 2000-04, Vol.118 (4), p.A182

2000

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555. Large-Scale, Flow-Based Electroporation To Deliver Engineered Zinc Finger Protein Nucleases That Mediate High-Efficiency Disruption of the Human CCR5 Gene

Molecular therapy, 2006-05, Vol.13 (S1), p.S214-S214

2006

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Preclinical evaluation for engraftment of CD34+ cells gene-edited at the sickle cell disease locus in xenograft mouse and non-human primate models

CRISPR-Cas9 gene repair of hematopoietic stem cells from patients with X-linked chronic granulomatous disease

Development of Anti-Human Mesothelin-Targeted Chimeric Antigen Receptor Messenger RNA-Transfected Peripheral Blood Lymphocytes for Ovarian Cancer Therapy

Influence of Helicobacter pylori on reactive oxygen-induced gastric epithelial cell injury

Gene Editing and mRNA-Based Therapy: Two Complementary Therapeutic Approaches for the Treatment of Patients with Xmen Disease

Preclinical Evaluation for Engraftment of Gene-Edited CD34+ Cells with a Sickle Cell Disease Mutation in a Rhesus Transplantation Model

Abstract 3748: Development of anti-human mesothelin chimeric antigen receptor (CAR) messenger RNA (mRNA) transfected peripheral blood mononuclear cells (CARMA) for the treatment of mesothelin-expressing cancers

MAGT1 messenger RNA-corrected autologous T and natural killer cells for potential cell therapy in X-linked immunodeficiency with magnesium defect, Epstein-Barr virus infection and neoplasia disease

Expression of chimeric antigen receptors in natural killer cells with a regulatory-compliant non-viral method

p53 and p14 increase sensitivity of gastric cells to H. pylori-induced apoptosis

Effects of Helicobacter pylori on proliferation of gastric epithelial cells in vitro

Efficient large volume lentiviral vector production using flow electroporation

Delivery of whole tumor lysate into dendritic cells for cancer vaccination

Large volume flow electroporation of mRNA: clinical scale process

Development of ‘enhanced’ potency immunotherapy products using nonviral approaches

A Highly Efficient, Clinically Applicable Transfection Method to Redirect the Specificity of Immune Cells and Enhance Their Anti-Tumor Capacity

An Improved, Non-Viral Approach for Production of hCD40L+ B-CLL Cells for Cancer Immunotherapy

Helicobacter pylori inhibits gastric cell cycle progression

A method for establishing primary cultures of human gastric epithelial cells

816. Rapid, Consistent and Scalable Production of Viral Vectors in Suspension Cells by Cotransfection of Viral Component Plasmid DNA or RNA

Highly Efficient, Large Volume Flow Electroporation

Efficient responses in a murine renal tumor model by electroloading dendritic cells with whole-tumor lysate

Stimulation of reactive oxygen species within gastric epithelial cells by H. pylori is responsible for the increase in p53 protein levels

H. pylori induced alterations in MDM2 and P14ARF expression in gastric epithelial cells

555. Large-Scale, Flow-Based Electroporation To Deliver Engineered Zinc Finger Protein Nucleases That Mediate High-Efficiency Disruption of the Human CCR5 Gene

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