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Sphingosine-1-Phosphate Links Persistent STAT3 Activation, Chronic Intestinal Inflammation, and Development of Colitis-Associated Cancer

Cancer cell, 2013-01, Vol.23 (1), p.107-120

2013

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Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration

The FASEB journal, 2011-02, Vol.25 (2), p.600-612

2011

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Sphingosine-1-Phosphate Produced by Sphingosine Kinase 1 Promotes Breast Cancer Progression by Stimulating Angiogenesis and Lymphangiogenesis

Cancer research (Chicago, Ill.), 2012-02, Vol.72 (3), p.726-735

2012

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A specific sphingosine kinase 1 inhibitor attenuates airway hyperresponsiveness and inflammation in a mast cell–dependent murine model of allergic asthma

Journal of allergy and clinical immunology, 2013-02, Vol.131 (2), p.501-511.e1

2013

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Conjugated bile acid–activated S1P receptor 2 is a key regulator of sphingosine kinase 2 and hepatic gene expression

Hepatology (Baltimore, Md.), 2015-04, Vol.61 (4), p.1216-1226

2015

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Targeting the SphK1/S1P/S1PR1 Axis That Links Obesity, Chronic Inflammation, and Breast Cancer Metastasis

Cancer research (Chicago, Ill.), 2018-04, Vol.78 (7), p.1713-1725

2018

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Circulating Ceramide 16:0 in Heart Failure With Preserved Ejection Fraction

Journal of the American College of Cardiology, 2020-05, Vol.75 (17), p.2273-2275

2020

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Active, phosphorylated fingolimod inhibits histone deacetylases and facilitates fear extinction memory

Nature neuroscience, 2014-07, Vol.17 (7), p.971-980

2014

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Aberrant ORM (yeast)–like protein isoform 3 (ORMDL3) expression dysregulates ceramide homeostasis in cells and ceramide exacerbates allergic asthma in mice

Journal of allergy and clinical immunology, 2015-10, Vol.136 (4), p.1035-1046.e6

2015

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Estradiol Induces Export of Sphingosine 1-Phosphate from Breast Cancer Cells via ABCC1 and ABCG2

The Journal of biological chemistry, 2010-04, Vol.285 (14), p.10477-10486

2010

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Calcium-stimulated disassembly of focal adhesions mediated by an ORP3/IQSec1 complex

eLife, 2020-04, Vol.9

2020

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Quantitative analysis of sphingolipids for lipidomics using triple quadrupole and quadrupole linear ion trap mass spectrometers[S]

Journal of lipid research, 2009-08, Vol.50 (8), p.1692-1707

2009

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Regulation of Histone Acetylation in the Nucleus by Sphingosine-1-Phosphate

Science (American Association for the Advancement of Science), 2009-09, Vol.325 (5945), p.1254-1257

2009

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Autophagy Induced by Deficiency of Sphingosine-1-phosphate Phosphohydrolase 1 Is Switched to Apoptosis by Calpain-mediated Autophagy-related Gene 5 (Atg5) Cleavage

The Journal of biological chemistry, 2011-12, Vol.286 (52), p.44380-44390

2011

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Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2

Nature (London), 2010-06, Vol.465 (7301), p.1084-1088

2010

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Sphingolipidomics: Methods for the comprehensive analysis of sphingolipids

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2009-09, Vol.877 (26), p.2696-2708

2009

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Spns2, a transporter of phosphorylated sphingoid bases, regulates their blood and lymph levels, and the lymphatic network

The FASEB journal, 2013-03, Vol.27 (3), p.1001-1011

2013

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Sphingolipidomics: High-throughput, structure-specific, and quantitative analysis of sphingolipids by liquid chromatography tandem mass spectrometry

Methods (San Diego, Calif.), 2005-06, Vol.36 (2), p.207-224

2005

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K63-linked polyubiquitination of transcription factor IRF1 is essential for IL-1-induced production of chemokines CXCL10 and CCL5

Nature immunology, 2014-03, Vol.15 (3), p.231

2014

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Ceramides and other bioactive sphingolipid backbones in health and disease: Lipidomic analysis, metabolism and roles in membrane structure, dynamics, signaling and autophagy

Biochimica et biophysica acta, 2006-12, Vol.1758 (12), p.1864-1884

2006

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Non-alcoholic fatty liver disease: Insights from sphingolipidomics

Biochemical and biophysical research communications, 2018-10, Vol.504 (3), p.608-616

2018

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Targeting Sphingosine Kinase 1 Inhibits Akt Signaling, Induces Apoptosis, and Suppresses Growth of Human Glioblastoma Cells and Xenografts

Cancer research (Chicago, Ill.), 2009-09, Vol.69 (17), p.6915-6923

2009

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Dynamics of sphingolipids and the serine palmitoyltransferase complex in rat oligodendrocytes during myelination[S]

Journal of lipid research, 2020-04, Vol.61 (4), p.505-522

2020

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Analysis of sphingolipids in human corneal fibroblasts from normal and keratoconus patients

Journal of lipid research, 2017-04, Vol.58 (4), p.636-648

2017

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Analysis of sphingolipid composition in human vitreous from control and diabetic individuals

Journal of diabetes and its complications, 2019-03, Vol.33 (3), p.195-201

2019

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Sphingosine-1-Phosphate Links Persistent STAT3 Activation, Chronic Intestinal Inflammation, and Development of Colitis-Associated Cancer

Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration

Sphingosine-1-Phosphate Produced by Sphingosine Kinase 1 Promotes Breast Cancer Progression by Stimulating Angiogenesis and Lymphangiogenesis

A specific sphingosine kinase 1 inhibitor attenuates airway hyperresponsiveness and inflammation in a mast cell–dependent murine model of allergic asthma

Conjugated bile acid–activated S1P receptor 2 is a key regulator of sphingosine kinase 2 and hepatic gene expression

Targeting the SphK1/S1P/S1PR1 Axis That Links Obesity, Chronic Inflammation, and Breast Cancer Metastasis

Circulating Ceramide 16:0 in Heart Failure With Preserved Ejection Fraction

Active, phosphorylated fingolimod inhibits histone deacetylases and facilitates fear extinction memory

Aberrant ORM (yeast)–like protein isoform 3 (ORMDL3) expression dysregulates ceramide homeostasis in cells and ceramide exacerbates allergic asthma in mice

Estradiol Induces Export of Sphingosine 1-Phosphate from Breast Cancer Cells via ABCC1 and ABCG2

Calcium-stimulated disassembly of focal adhesions mediated by an ORP3/IQSec1 complex

Quantitative analysis of sphingolipids for lipidomics using triple quadrupole and quadrupole linear ion trap mass spectrometers[S]

Regulation of Histone Acetylation in the Nucleus by Sphingosine-1-Phosphate

Autophagy Induced by Deficiency of Sphingosine-1-phosphate Phosphohydrolase 1 Is Switched to Apoptosis by Calpain-mediated Autophagy-related Gene 5 (Atg5) Cleavage

Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2

Sphingolipidomics: Methods for the comprehensive analysis of sphingolipids

Spns2, a transporter of phosphorylated sphingoid bases, regulates their blood and lymph levels, and the lymphatic network

Sphingolipidomics: High-throughput, structure-specific, and quantitative analysis of sphingolipids by liquid chromatography tandem mass spectrometry

K63-linked polyubiquitination of transcription factor IRF1 is essential for IL-1-induced production of chemokines CXCL10 and CCL5

Ceramides and other bioactive sphingolipid backbones in health and disease: Lipidomic analysis, metabolism and roles in membrane structure, dynamics, signaling and autophagy

Non-alcoholic fatty liver disease: Insights from sphingolipidomics

Targeting Sphingosine Kinase 1 Inhibits Akt Signaling, Induces Apoptosis, and Suppresses Growth of Human Glioblastoma Cells and Xenografts

Dynamics of sphingolipids and the serine palmitoyltransferase complex in rat oligodendrocytes during myelination[S]

Analysis of sphingolipids in human corneal fibroblasts from normal and keratoconus patients

Analysis of sphingolipid composition in human vitreous from control and diabetic individuals

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