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Visible‐Light‐Initiated Manganese Catalysis for C−H Alkylation of Heteroarenes: Applications and Mechanistic Studies

Angewandte Chemie (International ed.), 2017-11, Vol.56 (48), p.15309-15313

International ed. in English, 2017

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Enantio- and Diastereoselective Synthesis of 1,5-syn-(Z)‑Amino Alcohols via Imine Double Allylboration: Synthesis of trans-1,2,3,6-Tetrahydropyridines and Total Synthesis of Andrachcine

Organic letters, 2017-05, Vol.19 (10), p.2646-2649

2017

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Visible-Light-Driven Photocatalytic Initiation of Radical Thiol–Ene Reactions Using Bismuth Oxide

Organic letters, 2015-12, Vol.17 (23), p.5756-5759

2015

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Metal-Free Michael-Addition-Initiated Three-Component Reaction for the Regioselective Synthesis of Highly Functionalized Pyridines: Scope, Mechanistic Investigations and Applications

European journal of organic chemistry, 2013-07, Vol.2013 (19), p.4131-4145

2013

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Diisopinocampheylborane-Mediated Reductive Aldol Reactions: Highly Enantio- and Diastereoselective Synthesis of syn Aldols from N-Acryloylmorpholine

Angewandte Chemie (International ed.), 2013-08, Vol.52 (33), p.8703-8707

International ed. in English, 2013

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Discovery of a Series of Pyrimidine Carboxamides as Inhibitors of Vanin‑1

Journal of medicinal chemistry, 2022-01, Vol.65 (1), p.757-784

2022

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Development of the Commercial Manufacturing Process for Nirmatrelvir in 17 Months

ACS central science, 2023-05, Vol.9 (5), p.849-857

2023

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Access to Highly Substituted 7‑Azaindoles from 2‑Fluoropyridines via 7‑Azaindoline Intermediates

Organic letters, 2015-09, Vol.17 (17), p.4292-4295

2015

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Metal-Free Multicomponent Syntheses of Pyridines

Chemical reviews, 2014-11, Vol.114 (21), p.10829-10868

2014

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Use of β,γ-Unsaturated α-Ketocarbonyls for a Totally Regioselective Oxidative Multicomponent Synthesis of Polyfunctionalized Pyridines

Chemistry : a European journal, 2009-12, Vol.15 (47), p.12945-12948

2009

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Desymmetrization of Vicinal Bis(boronic) Esters by Enantioselective Suzuki–Miyaura Cross-Coupling Reaction

Journal of the American Chemical Society, 2023-04, Vol.145 (15), p.8308-8313

2023

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Visible‐Light‐Initiated Manganese Catalysis for C−H Alkylation of Heteroarenes: Applications and Mechanistic Studies

Angewandte Chemie, 2017-11, Vol.129 (48), p.15511-15515

2017

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Diisopinocampheylborane-Mediated Reductive Aldol Reactions: Highly Enantio- and Diastereoselective Synthesis of syn Aldols from N-Acryloylmorpholine

Angewandte Chemie, 2013-08, Vol.125 (33), p.8865-8869

2013

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Generation of Stereochemically Defined Tetrasubstituted Enolborinates by 1,4-Hydroboration of α,β-Unsaturated Morpholine Carboxamides with (Diisopinocampheyl)borane

Angewandte Chemie (International ed.), 2013-12, Vol.52 (49), p.12888-12891

2013

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Rapid Multikilogram Scale-Up of Di- and Trifluoromethoxy Proline Derivatives

Organic process research & development, 2024-04, Vol.28 (4), p.1119-1128

2024

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Diastereoselective Diboration of Cyclic Alkenes: Application to the Synthesis of Aristeromycin

Organic letters, 2021-04, Vol.23 (8), p.2863-2867

2021

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Construction of Azacycles by Intramolecular Amination of Organoboronates and Organobis(boronates)

Organic letters, 2021-05, Vol.23 (9), p.3379-3383

2021

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Early Process Development of Two Vanin-1 Inhibitors: Solid Form Challenges and Control of Ambident Reactivity

Organic process research & development, 2024-01

2024

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Stereocontrolled Pericyclic and Radical Cycloaddition Reactions of Readily Accessible Chiral Alkenyl Diazaborolidines

Angewandte Chemie (International ed.), 2022-07, Vol.61 (30), p.e202205454-n/a

International ed. in English, 2022

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(Diisopinocampheyl)borane-Mediated Reductive Aldol Reactions of Acrylate Esters: Enantioselective Synthesis of Anti-Aldols

Organic letters, 2013-08, Vol.15 (15), p.3922-3925

2013

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(Diisopinocampheyl)borane-Mediated Reductive Aldol Reactions: Highly Enantio and Diastereoselective Synthesis of Syn-Aldols from N-Acryloylmorpholine

Angewandte Chemie (International ed.), 2013-07, Vol.52 (33)

2013

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Metal-free Michael addition initiated multicomponent oxidative cyclodehydration route to polysubstituted pyridines from 1,3-dicarbonyls

Chemical communications (Cambridge, England), 2008-01 (35), p.4207-4209

2008

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Synthesis of Nirmatrelvir: Design and Optimization of an Efficient Telescoped Amidation–Dehydration Sequence

Organic process research & development, 2023-12, Vol.27 (12), p.2250-2259

2023

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Synthesis of Nirmatrelvir: Development of Magnesium Sulfate-Mediated Aminolysis for the Manufacture of the Eastern Fragment

Organic process research & development, 2023-12, Vol.27 (12), p.2271-2279

2023

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Synthesis of Nirmatrelvir: Development of a Scalable Cobalt-Catalyzed Cyclopropanation for Manufacture of the Bicyclic [3.1.0]Proline-Building Block

Organic process research & development, 2023-12, Vol.27 (12), p.2260-2270

2023

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Visible‐Light‐Initiated Manganese Catalysis for C−H Alkylation of Heteroarenes: Applications and Mechanistic Studies

Enantio- and Diastereoselective Synthesis of 1,5-syn-(Z)‑Amino Alcohols via Imine Double Allylboration: Synthesis of trans-1,2,3,6-Tetrahydropyridines and Total Synthesis of Andrachcine

Visible-Light-Driven Photocatalytic Initiation of Radical Thiol–Ene Reactions Using Bismuth Oxide

Metal-Free Michael-Addition-Initiated Three-Component Reaction for the Regioselective Synthesis of Highly Functionalized Pyridines: Scope, Mechanistic Investigations and Applications

Diisopinocampheylborane-Mediated Reductive Aldol Reactions: Highly Enantio- and Diastereoselective Synthesis of syn Aldols from N-Acryloylmorpholine

Discovery of a Series of Pyrimidine Carboxamides as Inhibitors of Vanin‑1

Development of the Commercial Manufacturing Process for Nirmatrelvir in 17 Months

Access to Highly Substituted 7‑Azaindoles from 2‑Fluoropyridines via 7‑Azaindoline Intermediates

Metal-Free Multicomponent Syntheses of Pyridines

Use of β,γ-Unsaturated α-Ketocarbonyls for a Totally Regioselective Oxidative Multicomponent Synthesis of Polyfunctionalized Pyridines

Desymmetrization of Vicinal Bis(boronic) Esters by Enantioselective Suzuki–Miyaura Cross-Coupling Reaction

Visible‐Light‐Initiated Manganese Catalysis for C−H Alkylation of Heteroarenes: Applications and Mechanistic Studies

Diisopinocampheylborane-Mediated Reductive Aldol Reactions: Highly Enantio- and Diastereoselective Synthesis of syn Aldols from N-Acryloylmorpholine

Generation of Stereochemically Defined Tetrasubstituted Enolborinates by 1,4-Hydroboration of α,β-Unsaturated Morpholine Carboxamides with (Diisopinocampheyl)borane

Rapid Multikilogram Scale-Up of Di- and Trifluoromethoxy Proline Derivatives

Diastereoselective Diboration of Cyclic Alkenes: Application to the Synthesis of Aristeromycin

Construction of Azacycles by Intramolecular Amination of Organoboronates and Organobis(boronates)

Early Process Development of Two Vanin-1 Inhibitors: Solid Form Challenges and Control of Ambident Reactivity

Stereocontrolled Pericyclic and Radical Cycloaddition Reactions of Readily Accessible Chiral Alkenyl Diazaborolidines

(Diisopinocampheyl)borane-Mediated Reductive Aldol Reactions of Acrylate Esters: Enantioselective Synthesis of Anti-Aldols

(Diisopinocampheyl)borane-Mediated Reductive Aldol Reactions: Highly Enantio and Diastereoselective Synthesis of Syn-Aldols from N-Acryloylmorpholine

Metal-free Michael addition initiated multicomponent oxidative cyclodehydration route to polysubstituted pyridines from 1,3-dicarbonyls

Synthesis of Nirmatrelvir: Design and Optimization of an Efficient Telescoped Amidation–Dehydration Sequence

Synthesis of Nirmatrelvir: Development of Magnesium Sulfate-Mediated Aminolysis for the Manufacture of the Eastern Fragment

Synthesis of Nirmatrelvir: Development of a Scalable Cobalt-Catalyzed Cyclopropanation for Manufacture of the Bicyclic [3.1.0]Proline-Building Block

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