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Senescence in chronic liver disease: Is the future in aging?

Journal of hepatology, 2016-10, Vol.65 (4), p.825-834

2016

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The British Society of Gastroenterology/UK-PBC primary biliary cholangitis treatment and management guidelines

Gut, 2018-09, Vol.67 (9), p.1568-1594

2018

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Hepatocyte expression of the senescence marker p21 is linked to fibrosis and an adverse liver-related outcome in alcohol-related liver disease

PloS one, 2013-09, Vol.8 (9), p.e72904

2013

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Chronic Hepatitis B Virus Infection: The Relation between Hepatitis B Antigen Expression, Telomere Length, Senescence, Inflammation and Fibrosis

PloS one, 2015-05, Vol.10 (5), p.e0127511-e0127511

2015

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Sustained telomere length in hepatocytes and cholangiocytes with increasing age in normal liver

Hepatology (Baltimore, Md.), 2012-10, Vol.56 (4), p.1510-1520

2012

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Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation

Nature biotechnology, 2015-08, Vol.33 (8), p.845-852

2015

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The senescent hepatocyte gene signature in chronic liver disease

Experimental gerontology, 2014-12, Vol.60, p.37-45

2014

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A viral discovery methodology for clinical biopsy samples utilising massively parallel next generation sequencing

PloS one, 2011-12, Vol.6 (12), p.e28879-e28879

2011

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Selective insulin resistance in hepatocyte senescence

Experimental cell research, 2015-02, Vol.331 (1), p.38-45

2015

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Sex and Age Are Determinants of the Clinical Phenotype of Primary Biliary Cirrhosis and Response to Ursodeoxycholic Acid

Gastroenterology (New York, N.Y. 1943), 2013-03, Vol.144 (3), p.560-569.e7

2013

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Regulatory T Cells Suppress In Vitro Proliferation of Virus-Specific CD8+ T Cells during Persistent Hepatitis C Virus Infection

Journal of Virology, 2005-06, Vol.79 (12), p.7852-7859

2005

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Persistence of Hepatitis C Virus Traces after Spontaneous Resolution of Hepatitis C

PloS one, 2015-10, Vol.10 (10), p.e0140312-e0140312

2015

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British Society of Gastroenterology and UK-PSC guidelines for the diagnosis and management of primary sclerosing cholangitis

Gut, 2019-08, Vol.68 (8), p.1356-1378

2019

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Hepatocyte senescence explains conjugated bilirubinaemia in chronic liver failure

Journal of hepatology, 2015-08, Vol.63 (2), p.532-533

2015

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Induced pluripotent stem cells: From Nobel Prizes to clinical applications

Journal of hepatology, 2013-03, Vol.58 (3), p.625-629

2013

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TM6SF2 rs58542926 influences hepatic fibrosis progression in patients with non-alcoholic fatty liver disease

Nature communications, 2014-06, Vol.5 (1), p.4309-4309, Article 4309

2014

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Tumour lymphocytic infiltrate and recurrence of hepatocellular carcinoma following liver transplantation

Journal of hepatology, 2006-08, Vol.45 (2), p.246-253

2006

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Compromised lymphocytes infiltrate hepatocellular carcinoma : The role of T-regulatory cells

Hepatology (Baltimore, Md.), 2005-04, Vol.41 (4), p.722-730

2005

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Impact of primary biliary cirrhosis on perceived quality of life: The UK‐PBC national study

Hepatology (Baltimore, Md.), 2013-07, Vol.58 (1), p.273-283

2013

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Reliability of magnetic resonance elastography using multislice two-dimensional spin-echo echo-planar imaging (SE-EPI) and three-dimensional inversion reconstruction for assessing renal stiffness

Journal of magnetic resonance imaging, 2015-09, Vol.42 (3), p.844-850

2015

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Amino acid residues in five separate HLA genes can explain most of the known associations between the MHC and primary biliary cholangitis

PLoS genetics, 2018-12, Vol.14 (12), p.e1007833

2018

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Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells

Nature (London), 2011-10, Vol.478 (7369), p.391-394

2011

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Genetic variation in IL28B and spontaneous clearance of hepatitis C virus

Nature (London), 2009-10, Vol.461 (7265), p.798-801

2009

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γ-H2AX + CD8+ T lymphocytes cannot respond to IFN-α, IL-2 or IL-6 in chronic hepatitis C virus infection

Journal of hepatology, 2013-05, Vol.58 (5), p.868-874

2013

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Senescence in chronic liver disease: Is the future in aging?

The British Society of Gastroenterology/UK-PBC primary biliary cholangitis treatment and management guidelines

Hepatocyte expression of the senescence marker p21 is linked to fibrosis and an adverse liver-related outcome in alcohol-related liver disease

Chronic Hepatitis B Virus Infection: The Relation between Hepatitis B Antigen Expression, Telomere Length, Senescence, Inflammation and Fibrosis

Sustained telomere length in hepatocytes and cholangiocytes with increasing age in normal liver

Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation

The senescent hepatocyte gene signature in chronic liver disease

A viral discovery methodology for clinical biopsy samples utilising massively parallel next generation sequencing

Selective insulin resistance in hepatocyte senescence

Sex and Age Are Determinants of the Clinical Phenotype of Primary Biliary Cirrhosis and Response to Ursodeoxycholic Acid

Regulatory T Cells Suppress In Vitro Proliferation of Virus-Specific CD8+ T Cells during Persistent Hepatitis C Virus Infection

Persistence of Hepatitis C Virus Traces after Spontaneous Resolution of Hepatitis C

British Society of Gastroenterology and UK-PSC guidelines for the diagnosis and management of primary sclerosing cholangitis

Hepatocyte senescence explains conjugated bilirubinaemia in chronic liver failure

Induced pluripotent stem cells: From Nobel Prizes to clinical applications

TM6SF2 rs58542926 influences hepatic fibrosis progression in patients with non-alcoholic fatty liver disease

Tumour lymphocytic infiltrate and recurrence of hepatocellular carcinoma following liver transplantation

Compromised lymphocytes infiltrate hepatocellular carcinoma : The role of T-regulatory cells

Impact of primary biliary cirrhosis on perceived quality of life: The UK‐PBC national study

Reliability of magnetic resonance elastography using multislice two-dimensional spin-echo echo-planar imaging (SE-EPI) and three-dimensional inversion reconstruction for assessing renal stiffness

Disease burden and costs from excess alcohol consumption, obesity, and viral hepatitis: fourth report of the Lancet Standing Commission on Liver Disease in the UK

Amino acid residues in five separate HLA genes can explain most of the known associations between the MHC and primary biliary cholangitis

Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells

Genetic variation in IL28B and spontaneous clearance of hepatitis C virus

γ-H2AX + CD8+ T lymphocytes cannot respond to IFN-α, IL-2 or IL-6 in chronic hepatitis C virus infection

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