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Co-regulation of the transcription controlling ATF2 phosphoswitch by JNK and p38

Nature communications, 2020-11, Vol.11 (1), p.5769-5769, Article 5769

2020

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Targeting a key protein-protein interaction surface on mitogen-activated protein kinases by a precision-guided warhead scaffold

Nature communications, 2024-10, Vol.15 (1), p.8607-22, Article 8607

2024

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Reversible covalent c-Jun N-terminal kinase inhibitors targeting a specific cysteine by precision-guided Michael-acceptor warheads

Nature communications, 2024-10, Vol.15 (1), p.8606-19, Article 8606

2024

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A non-catalytic herpesviral protein reconfigures ERK-RSK signaling by targeting kinase docking systems in the host

Nature communications, 2022-01, Vol.13 (1), p.472-472, Article 472

2022

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Phosphorylation-Assisted Luciferase Complementation Assay Designed to Monitor Kinase Activity and Kinase-Domain-Mediated Protein–Protein Binding

International journal of molecular sciences, 2023-10, Vol.24 (19), p.14854

2023

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Structural assembly of the signaling competent ERK2–RSK1 heterodimeric protein kinase complex

Proceedings of the National Academy of Sciences - PNAS, 2015-03, Vol.112 (9), p.2711-2716

2015

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Structural Basis of Ribosomal S6 Kinase 1 (RSK1) Inhibition by S100B Protein

The Journal of biological chemistry, 2016-01, Vol.291 (1), p.11-27

2016

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Peptide Based Inhibitors of Protein Binding to the Mitogen-Activated Protein Kinase Docking Groove

Frontiers in molecular biosciences, 2021-07, Vol.8, p.690429-690429

2021

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Conformations of P90 Ribosomal S6 Kinase Activation

Biophysical journal, 2020-02, Vol.118 (3), p.336a-336a

2020

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Exploration of Protein Regions Involved in Map Kinase Mediated Signaling

Biophysical journal, 2017-02, Vol.112 (3), p.12a-12a

2017

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Discovery and Characterization of Linear Motif Mediated Protein-Protein Complexes

Advanced Technologies for Protein Complex Production and Characterization, 2024, Vol.1453, p.59-71

2024

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Contribution of Distinct Structural Elements to Activation of Calpain by Ca2+ Ions

The Journal of biological chemistry, 2004-05, Vol.279 (19), p.20118-20126

2004

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Structural Basis of Ribosomal S6 Kinase 1 (RSK1) Inhibition by S100B Protein: MODULATION OF THE EXTRACELLULAR SIGNAL-REGULATED KINASE (ERK) SIGNALING CASCADE IN A CALCIUM-DEPENDENT WAY

The Journal of biological chemistry, 2016-01, Vol.291 (1), p.11-27

2016

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MAP Kinase-Mediated Activation of RSK1 and MK2 Substrate Kinases

Structure (London), 2020-10, Vol.28 (10), p.1101-1113.e5

2020

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Structural Mechanism for the Specific Assembly and Activation of the Extracellular Signal Regulated Kinase 5 (ERK5) Module

The Journal of biological chemistry, 2013-03, Vol.288 (12), p.8596-8609

2013

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Specificity of linear motifs that bind to a common mitogen-activated protein kinase docking groove

Science signaling, 2012-10, Vol.5 (245), p.ra74

2012

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Systematic discovery of linear binding motifs targeting an ancient protein interaction surface on MAP kinases

Molecular systems biology, 2015-11, Vol.11 (11), p.837-n/a

2015

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Theileria highjacks JNK2 into a complex with the macroschizont GPI (GlycosylPhosphatidylInositol)‐anchored surface protein p104

Cellular microbiology, 2019-03, Vol.21 (3), p.e12973-n/a

2019

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Dynamic control of RSK complexes by phosphoswitch‐based regulation

The FEBS journal, 2018-01, Vol.285 (1), p.46-71

2018

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The NM23-H1/H2 homolog NDK-1 is required for full activation of Ras signaling in C. elegans

Development (Cambridge), 2013-08, Vol.140 (16), p.3486-3495

2013

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Scaffolds are 'active' regulators of signaling modules

The FEBS journal, 2010-11, Vol.277 (21), p.4376-4382

2010

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Novel Cell-Penetrating Calpain Substrate

Bioconjugate chemistry, 2008-07, Vol.19 (7), p.1375-1381

2008

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Multiple interactions of the 'transducer' govern its function in calpain activation by Ca2

Biochemical journal, 2005-06, Vol.388 (Pt 3), p.741-744

2005

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Identifying calpain substrates in intact S2 cells of Drosophila

Archives of biochemistry and biophysics, 2009-01, Vol.481 (2), p.219-225

2009

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Regulation of calpain B from Drosophila melanogaster by phosphorylation

The FEBS journal, 2009-09, Vol.276 (17), p.4959-4972

2009

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Co-regulation of the transcription controlling ATF2 phosphoswitch by JNK and p38

Targeting a key protein-protein interaction surface on mitogen-activated protein kinases by a precision-guided warhead scaffold

Reversible covalent c-Jun N-terminal kinase inhibitors targeting a specific cysteine by precision-guided Michael-acceptor warheads

A non-catalytic herpesviral protein reconfigures ERK-RSK signaling by targeting kinase docking systems in the host

Phosphorylation-Assisted Luciferase Complementation Assay Designed to Monitor Kinase Activity and Kinase-Domain-Mediated Protein–Protein Binding

Structural assembly of the signaling competent ERK2–RSK1 heterodimeric protein kinase complex

Structural Basis of Ribosomal S6 Kinase 1 (RSK1) Inhibition by S100B Protein

Peptide Based Inhibitors of Protein Binding to the Mitogen-Activated Protein Kinase Docking Groove

Conformations of P90 Ribosomal S6 Kinase Activation

Exploration of Protein Regions Involved in Map Kinase Mediated Signaling

Discovery and Characterization of Linear Motif Mediated Protein-Protein Complexes

Contribution of Distinct Structural Elements to Activation of Calpain by Ca2+ Ions

Structural Basis of Ribosomal S6 Kinase 1 (RSK1) Inhibition by S100B Protein: MODULATION OF THE EXTRACELLULAR SIGNAL-REGULATED KINASE (ERK) SIGNALING CASCADE IN A CALCIUM-DEPENDENT WAY

MAP Kinase-Mediated Activation of RSK1 and MK2 Substrate Kinases

Structural Mechanism for the Specific Assembly and Activation of the Extracellular Signal Regulated Kinase 5 (ERK5) Module

Specificity of linear motifs that bind to a common mitogen-activated protein kinase docking groove

Systematic discovery of linear binding motifs targeting an ancient protein interaction surface on MAP kinases

Theileria highjacks JNK2 into a complex with the macroschizont GPI (GlycosylPhosphatidylInositol)‐anchored surface protein p104

Dynamic control of RSK complexes by phosphoswitch‐based regulation

The NM23-H1/H2 homolog NDK-1 is required for full activation of Ras signaling in C. elegans

Scaffolds are 'active' regulators of signaling modules

Novel Cell-Penetrating Calpain Substrate

Multiple interactions of the 'transducer' govern its function in calpain activation by Ca2

Identifying calpain substrates in intact S2 cells of Drosophila

Regulation of calpain B from Drosophila melanogaster by phosphorylation

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